Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myb

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYB
- Mouse genes Myb
- Rat genes Myb
- Zfish genes myb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Myb	IDA		Mouse	PMID:12628004
Molecular Function	GO:0003677	DNA binding	Myb	IDA		Mouse	PMID:21980308
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MYB	IDA		Human	PMID:10233885
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MYB	IDA		Human	PMID:25857263
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Myb	IDA		Mouse	MGI:MGI:5572893\|PMID:12244173
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myb	IMP		Mouse	PMID:12660151
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myb	IDA		Mouse	PMID:12628004
Molecular Function	GO:0003700	DNA-binding transcription factor activity	myb	IDA		Zfish	PMID:27268086
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	myb	IDA		Zfish	PMID:27268086
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	myb	IGI	ZFIN:ZDB-GENE-010611-1	Zfish	PMID:27268086
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:Q9Y4K3	Human	PMID:18093978
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:Q00610	Human	PMID:18548008
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:O15083	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:O60293	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:O00255	Human	PMID:20484083
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:P23771	Human	PMID:20484083
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:P61956	Human	PMID:20802522
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:P63165	Human	PMID:20802522
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:P17542	Human	PMID:25394790
Molecular Function	GO:0005515	protein binding	MYB	IPI	UniProtKB:Q9H074-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Myb	IPI	UniProtKB:Q9QZR5	Mouse	MGI:MGI:3040155\|PMID:15082531
Molecular Function	GO:0005515	protein binding	Myb	IPI	UniProtKB:P38531	Mouse	MGI:MGI:6101274\|PMID:9211854
Molecular Function	GO:0005515	protein binding	Myb	IPI	PR:Q7TPV4	Mouse	PMID:8302594
Molecular Function	GO:0005515	protein binding	Myb	IPI	PR:B2RWS6	Mouse	PMID:18684867
Molecular Function	GO:0005515	protein binding	Myb	IPI	PR:Q922B6	Mouse	PMID:16162816
Molecular Function	GO:0005515	protein binding	myb	IPI	ZFIN:ZDB-GENE-010611-1	Zfish	PMID:27268086
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MYB	IDA		Human	PMID:25857263
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MYB	IDA		Human	PMID:7987850
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Myb	IDA		Mouse	MGI:MGI:5572893\|PMID:12244173
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	myb	IDA		Zfish	PMID:27268086
Molecular Function	GO:0071987	WD40-repeat domain binding	Myb	IDA		Mouse	PMID:16162816
Cellular Component	GO:0000785	chromatin	myb	IDA		Zfish	PMID:27268086
Cellular Component	GO:0005829	cytosol	MYB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Myb	IDA		Mouse	PMID:16162816
Cellular Component	GO:0005654	nucleoplasm	MYB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Myb	IDA		Mouse	PMID:12628004
Cellular Component	GO:0005634	nucleus	Myb	IDA		Mouse	PMID:16162816
Cellular Component	GO:0005634	nucleus	Myb	IDA		Mouse	PMID:8302594
Cellular Component	GO:0005634	nucleus	Myb	IDA		Mouse	PMID:16847320
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MYB	EXP		Human	PMID:11792321
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Myb	EXP		Mouse	MGI:MGI:2158117\|PMID:11792321
Biological Process	GO:0030183	B cell differentiation	Myb	IMP	MGI:MGI:3047076	Mouse	PMID:17927961
Biological Process	GO:0006816	calcium ion transport	Myb	IMP		Mouse	PMID:12660151
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Myb	IEP		Rat	PMID:23824072\|RGD:11532746
Biological Process	GO:0071354	cellular response to interleukin-6	Myb	IDA		Mouse	PMID:16162816
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Myb	IEP		Mouse	PMID:20439489
Biological Process	GO:0071300	cellular response to retinoic acid	Myb	IEP		Rat	PMID:8670250\|RGD:11532681
Biological Process	GO:0043009	chordate embryonic development	myb	IMP	ZFIN:ZDB-MRPHLNO-100503-18	Zfish	PMID:18667440
Biological Process	GO:0043009	chordate embryonic development	myb	IGI	ZFIN:ZDB-GENE-081125-1	Zfish	PMID:18667440
Biological Process	GO:0060271	cilium assembly	myb	IMP	ZFIN:ZDB-GENO-130204-1	Zfish	PMID:23698347
Biological Process	GO:0060271	cilium assembly	myb	IGI	ZFIN:ZDB-MRPHLNO-101015-3,ZFIN:ZDB-MRPHLNO-130808-5	Zfish	PMID:23698347
Biological Process	GO:0060216	definitive hemopoiesis	myb	IMP	ZFIN:ZDB-GENO-110107-1	Zfish	PMID:20823231
Biological Process	GO:0060216	definitive hemopoiesis	myb	IMP	ZFIN:ZDB-GENO-130204-1	Zfish	PMID:21856868
Biological Process	GO:0048566	embryonic digestive tract development	Myb	IMP	MGI:MGI:2662859	Mouse	PMID:10523863
Biological Process	GO:0030218	erythrocyte differentiation	MYB	IMP		Human	PMID:25857263
Biological Process	GO:0001654	eye development	myb	IMP	ZFIN:ZDB-MRPHLNO-100503-18	Zfish	PMID:18667440
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Myb	IMP		Mouse	PMID:12660151
Biological Process	GO:0035701	hematopoietic stem cell migration	myb	IGI	ZFIN:ZDB-GENO-130204-7,ZFIN:ZDB-MRPHLNO-051028-2	Zfish	PMID:21856868
Biological Process	GO:0048872	homeostasis of number of cells	Myb	IMP	MGI:MGI:3047076	Mouse	PMID:17927961
Biological Process	GO:0001701	in utero embryonic development	Myb	IMP	MGI:MGI:3047076	Mouse	PMID:17927961
Biological Process	GO:0001701	in utero embryonic development	Myb	IMP	MGI:MGI:2662859	Mouse	PMID:10523863
Biological Process	GO:0030099	myeloid cell differentiation	Myb	IMP	MGI:MGI:2677048	Mouse	PMID:19360001
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	MYB	IMP		Human	PMID:20531406
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	MYB	IMP		Human	PMID:28111278
Biological Process	GO:0045653	negative regulation of megakaryocyte differentiation	MYB	IMP		Human	PMID:25857263
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYB	IMP		Human	PMID:20531406
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Myb	IMP		Rat	PMID:15534927\|RGD:11532676
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MYB	IMP		Human	PMID:20531406
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Myb	IMP		Rat	PMID:12599418\|RGD:11532679
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	Myb	IMP		Rat	PMID:10666057\|RGD:11532677
Biological Process	GO:1904899	positive regulation of hepatic stellate cell proliferation	Myb	IMP		Rat	PMID:15534927\|RGD:11532676
Biological Process	GO:1902895	positive regulation of miRNA transcription	MYB	IDA		Human	PMID:25857263
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Myb	IMP		Rat	PMID:15470138\|RGD:11532747
Biological Process	GO:1901216	positive regulation of neuron death	Myb	IMP		Rat	PMID:24828495\|RGD:11532683
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Myb	IMP		Rat	PMID:8665409\|RGD:11532682
Biological Process	GO:2000845	positive regulation of testosterone secretion	Myb	IMP		Rat	PMID:15224149\|RGD:11532680
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	IDA		Human	PMID:10233885
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	EXP		Human	PMID:11792321
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	IDA		Human	PMID:20484083
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	IMP		Human	PMID:20484083
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	IMP		Human	PMID:20531406
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYB	IDA		Human	PMID:25857263
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myb	IDA		Mouse	MGI:MGI:5572893\|PMID:12244173
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myb	EXP		Mouse	MGI:MGI:2158117\|PMID:11792321
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myb	IGI	MGI:MGI:96770	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myb	IGI	MGI:MGI:97489	Mouse	PMID:15094381
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myb	IGI	MGI:MGI:1338823	Mouse	PMID:15094381
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	Myb	IMP		Rat	PMID:15534927\|RGD:11532676
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myb	IDA		Mouse	PMID:12628004
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myb	IMP		Mouse	PMID:12660151
Biological Process	GO:0010468	regulation of gene expression	Myb	IMP	MGI:MGI:2662859	Mouse	PMID:10523863
Biological Process	GO:0010468	regulation of gene expression	Myb	IMP	MGI:MGI:2677048	Mouse	PMID:19360001
Biological Process	GO:0045658	regulation of neutrophil differentiation	myb	IMP	ZFIN:ZDB-GENO-161202-2	Zfish	PMID:27268086
Biological Process	GO:0045658	regulation of neutrophil differentiation	myb	IGI	ZFIN:ZDB-GENE-010611-1	Zfish	PMID:27268086
Biological Process	GO:0001666	response to hypoxia	Myb	IEP		Rat	PMID:10074303\|RGD:11532745
Biological Process	GO:0014856	skeletal muscle cell proliferation	Myb	IEP		Rat	PMID:2447874\|RGD:151665807
Biological Process	GO:0048536	spleen development	Myb	IMP	MGI:MGI:2677048	Mouse	PMID:19360001
Biological Process	GO:0017145	stem cell division	Myb	IMP	MGI:MGI:2677048	Mouse	PMID:19360001
Biological Process	GO:0045064	T-helper 2 cell differentiation	MYB	IMP		Human	PMID:20484083
Biological Process	GO:0048538	thymus development	Myb	IMP	MGI:MGI:3047076	Mouse	PMID:17927961

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.