Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myc

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYC
- Mouse genes Myc
- Rat genes Myc
- Zfish genes myca,mycb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Myc	IDA		Mouse	PMID:15511642
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	MYC	IDA		Human	PMID:30873824
Molecular Function	GO:0003677	DNA binding	Myc	IDA		Mouse	PMID:14560010
Molecular Function	GO:0003677	DNA binding	Myc	IDA		Mouse	PMID:12970171
Molecular Function	GO:0003677	DNA binding	Myc	IDA		Rat	PMID:11799123\|RGD:619701
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MYC	IDA		Human	PMID:10723141
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MYC	IDA		Human	PMID:27791094
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myc	IDA		Rat	PMID:15139290\|RGD:1601462
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myc	IMP		Rat	PMID:17341548\|RGD:2290581
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	MYC	IMP		Human	PMID:25956029
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	MYC	IDA		Human	PMID:9924025
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	mycb	IPI	ZFIN:ZDB-GENE-040426-747	Zfish	PMID:30606747
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	mycb	IPI	ZFIN:ZDB-GENE-980526-90	Zfish	PMID:30606747
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MYC	IPI	UniProtKB:P25490	Human	PMID:15674325
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MYC	IPI	UniProtKB:P61244	Human	PMID:15674325
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MYC	IPI	UniProtKB:Q13105	Human	PMID:19160485
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MYC	IMP		Human	PMID:19786833
Molecular Function	GO:0003690	double-stranded DNA binding	Myc	IDA		Rat	PMID:15139290\|RGD:1601462
Molecular Function	GO:0070888	E-box binding	MYC	IDA		Human	PMID:18818310
Molecular Function	GO:0070888	E-box binding	MYC	IDA		Human	PMID:27791094
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13287	Human	PMID:10597290
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P52164	Human	PMID:11891322
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8IY57	Human	PMID:12706874
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:15103331
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P20226,UniProtKB:Q99471	Human	PMID:15663936
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O00499-10	Human	PMID:15992821
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O00499-11	Human	PMID:15992821
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:16352593
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13105	Human	PMID:16352593
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:16606833
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P0CG48	Human	PMID:16996503
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P03129	Human	PMID:17070091
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P04020	Human	PMID:17070091
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P06788	Human	PMID:17070091
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:17157259
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13309	Human	PMID:17157259
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8TAD8	Human	PMID:17157259
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:17157259
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O00629	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P03070	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P11387	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P33993	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q14839	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q15029	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8N163	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8N3Y1	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q92769	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96L91	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y2X9	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y4A5	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y5Q9	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O75928	Human	PMID:17418410
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P08047	Human	PMID:17418410
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:17418410
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P62913	Human	PMID:17599065
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8TCG1	Human	PMID:17632056
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0-1	Human	PMID:17873522
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96RU2	Human	PMID:17873522
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P03204	Human	PMID:18256156
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O43524	Human	PMID:18393360
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96L91	Human	PMID:18413597
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96L91-2	Human	PMID:18413597
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:18620061
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13105	Human	PMID:18923429
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O15169	Human	PMID:19131971
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P0CG48	Human	PMID:19131971
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13526	Human	PMID:19131971
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y6K1	Human	PMID:19786833
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P11387	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P17480	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q15059	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q86XR8	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q92769	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q14669	Human	PMID:20208519
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8TEL6	Human	PMID:20551172
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:20691906
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P49841-2	Human	PMID:20713710
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y6K9	Human	PMID:20970423
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P0CG48	Human	PMID:21150319
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P17480	Human	PMID:21150319
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:21150319
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96L91	Human	PMID:21150319
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y4A5	Human	PMID:21150319
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O15111	Human	PMID:21575199
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:21807113
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96EB6	Human	PMID:21807113
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P11802	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P11802	Human	PMID:22094256
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O15379	Human	PMID:23079660
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q8N6T7	Human	PMID:23217706
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:23791182
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:A9UHW6	Human	PMID:23804756
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O95983	Human	PMID:24048479
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O75182	Human	PMID:24951594
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:24951594
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q62141	Human	PMID:24951594
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P06748	Human	PMID:25956029
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:26267534
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9UBB4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13526	Human	PMID:26655473
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13105	Human	PMID:26766587
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:28007894
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O60341	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:A5D8W4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P06307	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P31948	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P45973	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q00403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9UBB4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:O00629	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P61244	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q969H0	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q96L91	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y4A5	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:P13393,UniProtKB:P41896	Human	PMID:8755740
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q13105	Human	PMID:9308237
Molecular Function	GO:0005515	protein binding	MYC	IPI	UniProtKB:Q9Y4A5	Human	PMID:9708738
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P28574	Mouse	MGI:MGI:4889165\|PMID:20946988
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P28574	Mouse	MGI:MGI:5142396\|PMID:9764821
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P06803	Mouse	MGI:MGI:5294288\|PMID:18438430
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:Q62070	Mouse	MGI:MGI:5294288\|PMID:18438430
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:Q8CH72	Mouse	MGI:MGI:3836317\|PMID:19269368
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P20263\|UniProtKB:Q80U70\|UniProtKB:Q80Z64\|UniProtKB:Q62315	Mouse	MGI:MGI:5887185\|PMID:26523946
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P28574	Mouse	MGI:MGI:4839428\|PMID:20434984
Molecular Function	GO:0005515	protein binding	Myc	IPI	UniProtKB:P28574	Mouse	MGI:MGI:4455093\|PMID:20211142
Molecular Function	GO:0005515	protein binding	Myc	IPI	PR:Q9Z0Z3	Mouse	PMID:23277542
Molecular Function	GO:0005515	protein binding	Myc	IPI	MGI:MGI:104738	Mouse	PMID:23277542
Molecular Function	GO:0005515	protein binding	Myc	IPI	RGD:1310609	Rat	PMID:17334388\|RGD:9587456
Molecular Function	GO:0005515	protein binding	Myc	IPI	RGD:1562975	Rat	PMID:20418916\|RGD:9588315
Molecular Function	GO:0044877	protein-containing complex binding	MYC	IDA		Human	PMID:18987311
Molecular Function	GO:0044877	protein-containing complex binding	Myc	IPI	RGD:621101	Rat	PMID:17341548\|RGD:2290581
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MYC	IDA		Human	PMID:10723141
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MYC	IMP		Human	PMID:19786833
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Myc	IDA		Mouse	PMID:18625840
Molecular Function	GO:0043565	sequence-specific DNA binding	Myc	IDA		Rat	PMID:15139290\|RGD:1601462
Molecular Function	GO:0043565	sequence-specific DNA binding	Myc	IDA		Rat	PMID:17341548\|RGD:2290581
Molecular Function	GO:0001221	transcription coregulator binding	MYC	IPI	UniProtKB:P19338	Human	PMID:15674325
Molecular Function	GO:0001221	transcription coregulator binding	MYC	IPI	UniProtKB:Q09472	Human	PMID:15674325
Molecular Function	GO:0001221	transcription coregulator binding	MYC	IPI	UniProtKB:Q53GL7	Human	PMID:15674325
Molecular Function	GO:0001221	transcription coregulator binding	MYC	IPI	UniProtKB:Q92793	Human	PMID:15674325
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Myc	IPI	UniProtKB:Q8BGE7	Mouse	MGI:MGI:5492022\|PMID:22328504
Cellular Component	GO:0030424	axon	Myc	IDA		Mouse	PMID:10482234
Cellular Component	GO:0000785	chromatin	MYC	IMP		Human	PMID:12837246
Cellular Component	GO:0005737	cytoplasm	Myc	IDA		Rat	PMID:9130602\|RGD:1599896
Cellular Component	GO:0000791	euchromatin	Myc	IDA		Mouse	MGI:MGI:5428344\|PMID:22723415
Cellular Component	GO:0071943	Myc-Max complex	MYC	IPI		Human	PMID:12553908
Cellular Component	GO:0071943	Myc-Max complex	Myc	IPI		Mouse	MGI:MGI:4839428\|PMID:20434984
Cellular Component	GO:0016604	nuclear body	Myc	IDA		Mouse	PMID:15735755
Cellular Component	GO:0005730	nucleolus	MYC	IDA		Human	PMID:17558397
Cellular Component	GO:0005730	nucleolus	MYC	IDA		Human	PMID:25775507
Cellular Component	GO:0005730	nucleolus	Myc	IDA		Rat	PMID:15777849\|RGD:2290580
Cellular Component	GO:0005730	nucleolus	Myc	IDA		Rat	PMID:16150871\|RGD:1581930
Cellular Component	GO:0005654	nucleoplasm	MYC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MYC	IDA		Human	PMID:17558397
Cellular Component	GO:0005634	nucleus	MYC	IDA		Human	PMID:11793365
Cellular Component	GO:0005634	nucleus	MYC	IDA		Human	PMID:15358760
Cellular Component	GO:0005634	nucleus	MYC	IDA		Human	PMID:15994933
Cellular Component	GO:0005634	nucleus	MYC	IDA		Human	PMID:18393360
Cellular Component	GO:0005634	nucleus	MYC	IDA		Human	PMID:8782822
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	MGI:MGI:5492022\|PMID:22328504
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	PMID:23770341
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	PMID:17631878
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	PMID:11872843
Cellular Component	GO:0005634	nucleus	Myc	IDA		Mouse	PMID:18625840
Cellular Component	GO:0005634	nucleus	Myc	IDA		Rat	PMID:16150871\|RGD:1581930
Cellular Component	GO:0005634	nucleus	Myc	IDA		Rat	PMID:9130602\|RGD:1599896
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myc	IDA		Mouse	MGI:MGI:5492022\|PMID:22328504
Cellular Component	GO:0032991	protein-containing complex	MYC	IDA		Human	PMID:17873522
Cellular Component	GO:0032991	protein-containing complex	MYC	IDA		Human	PMID:19160485
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	MYC	IPI		Human	PMID:15992821
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	MYC	IPI		Human	PMID:18393360
Cellular Component	GO:0005819	spindle	Myc	IDA		Mouse	PMID:15509711
Biological Process	GO:1990863	acinar cell proliferation	Myc	IGI	MGI:MGI:88039	Mouse	PMID:17596282
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Myc	IDA		Mouse	PMID:14517295
Biological Process	GO:0006865	amino acid transport	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0001783	B cell apoptotic process	Myc	IMP	MGI:MGI:1931143	Mouse	PMID:12970677
Biological Process	GO:0001783	B cell apoptotic process	Myc	IGI	MGI:MGI:99702	Mouse	PMID:11604501
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Myc	IMP		Mouse	MGI:MGI:3830398\|PMID:19161241
Biological Process	GO:0008283	cell population proliferation	Myc	IGI	MGI:MGI:88039	Mouse	PMID:17596282
Biological Process	GO:0008283	cell population proliferation	Myc	IMP		Rat	PMID:20639453\|RGD:7207820
Biological Process	GO:1904385	cellular response to angiotensin	Myc	IEP		Rat	PMID:17886230\|RGD:10059617
Biological Process	GO:1903841	cellular response to arsenite(3-)	Myc	IEP		Rat	PMID:9848127\|RGD:10059616
Biological Process	GO:0071322	cellular response to carbohydrate stimulus	Myc	IEP		Rat	PMID:20694826\|RGD:7240697
Biological Process	GO:0071409	cellular response to cycloheximide	Myc	IEP		Rat	PMID:11550711\|RGD:10059610
Biological Process	GO:0071345	cellular response to cytokine stimulus	Myc	IEP		Rat	PMID:11687580\|RGD:70227
Biological Process	GO:1904620	cellular response to dimethyl sulfoxide	Myc	IEP		Rat	PMID:12873812\|RGD:10059626
Biological Process	GO:1990859	cellular response to endothelin	Myc	IEP		Rat	PMID:16365184\|RGD:10059627
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Myc	IEP		Rat	PMID:7524476\|RGD:10059620
Biological Process	GO:0071391	cellular response to estrogen stimulus	Myc	IEP		Rat	PMID:21980073\|RGD:7241005
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Myc	IEP		Rat	PMID:7524476\|RGD:10059620
Biological Process	GO:0071378	cellular response to growth hormone stimulus	Myc	IEP		Rat	PMID:11550711\|RGD:10059610
Biological Process	GO:0071464	cellular response to hydrostatic pressure	Myc	IEP		Rat	PMID:22644739\|RGD:7240524
Biological Process	GO:0071456	cellular response to hypoxia	MYC	IDA		Human	PMID:15459207
Biological Process	GO:0032869	cellular response to insulin stimulus	Myc	IEP		Rat	PMID:2200903\|RGD:10059628
Biological Process	GO:0035457	cellular response to interferon-alpha	Myc	IDA		Mouse	PMID:24795346
Biological Process	GO:0071347	cellular response to interleukin-1	Myc	IEP		Rat	PMID:22706317\|RGD:7240518
Biological Process	GO:1990858	cellular response to lectin	Myc	IEP		Rat	PMID:2200903\|RGD:10059628
Biological Process	GO:0071407	cellular response to organic cyclic compound	Myc	IEP		Rat	PMID:21980073\|RGD:7241005
Biological Process	GO:1904628	cellular response to phorbol 13-acetate 12-myristate	Myc	IEP		Rat	PMID:2200903\|RGD:10059628
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Myc	IEP		Rat	PMID:7524476\|RGD:10059620
Biological Process	GO:1990646	cellular response to prolactin	Myc	IEP		Rat	PMID:9296381\|RGD:61637
Biological Process	GO:1904586	cellular response to putrescine	Myc	IEP		Rat	PMID:8048943\|RGD:10059622
Biological Process	GO:0071300	cellular response to retinoic acid	Myc	IEP		Rat	PMID:12873812\|RGD:10059626
Biological Process	GO:0071394	cellular response to testosterone stimulus	Myc	IEP		Rat	PMID:7721656\|RGD:11532758
Biological Process	GO:0071346	cellular response to type II interferon	Myc	IEP		Rat	PMID:7524476\|RGD:10059620
Biological Process	GO:0034644	cellular response to UV	MYC	IEP		Human	PMID:17873522
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	MYC	IDA		Human	PMID:17873522
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	MYC	IDA		Human	PMID:19179467
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Myc	IDA		Mouse	MGI:MGI:5306576\|PMID:19179467
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Myc	IEP		Rat	PMID:17886230\|RGD:10059617
Biological Process	GO:0006338	chromatin remodeling	MYC	IDA		Human	PMID:21533051
Biological Process	GO:0051276	chromosome organization	MYC	IDA		Human	PMID:10962037
Biological Process	GO:0060216	definitive hemopoiesis	mycb	IMP	ZFIN:ZDB-MRPHLNO-150611-3	Zfish	PMID:25714926
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	Myc	IMP	MGI:MGI:2178233,MGI:MGI:2386570	Mouse	PMID:17523175
Biological Process	GO:0006974	DNA damage response	MYC	IDA		Human	PMID:17873522
Biological Process	GO:0006974	DNA damage response	Myc	IDA		Mouse	PMID:20212154
Biological Process	GO:0006351	DNA-templated transcription	Myc	IDA		Rat	PMID:15139290\|RGD:1601462
Biological Process	GO:0006352	DNA-templated transcription initiation	Myc	IDA		Rat	PMID:3306601\|RGD:69897
Biological Process	GO:0070371	ERK1 and ERK2 cascade	MYC	IDA		Human	PMID:15459207
Biological Process	GO:0045023	G0 to G1 transition	Myc	IEP		Rat	PMID:23119170\|RGD:7207882
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	MYC	IDA		Human	PMID:25438055
Biological Process	GO:0006006	glucose metabolic process	Myc	IMP		Rat	PMID:12480946\|RGD:1581934
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mycb	IMP	ZFIN:ZDB-MRPHLNO-150611-3	Zfish	PMID:25714926
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mycb	IGI	ZFIN:ZDB-GENE-040724-269,ZFIN:ZDB-GENE-050624-1	Zfish	PMID:25714926
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mycb	IGI	ZFIN:ZDB-GENE-030404-2	Zfish	PMID:25714926
Biological Process	GO:0060218	hematopoietic stem cell differentiation	myca	IGI	ZFIN:ZDB-GENE-060825-97	Zfish	PMID:27806298
Biological Process	GO:0021854	hypothalamus development	Myc	IEP		Rat	PMID:23291449\|RGD:7207858
Biological Process	GO:0001701	in utero embryonic development	Myc	IEP		Rat	PMID:23077551\|RGD:7207883
Biological Process	GO:0007007	inner mitochondrial membrane organization	Myc	IMP		Rat	PMID:22629444\|RGD:7240532
Biological Process	GO:0006879	intracellular iron ion homeostasis	MYC	IDA		Human	PMID:9924025
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Myc	IMP	MGI:MGI:2447604	Mouse	PMID:14517295
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Myc	IDA		Mouse	PMID:14517295
Biological Process	GO:0046722	lactic acid secretion	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0097421	liver regeneration	Myc	IEP		Rat	PMID:3335218\|RGD:10059623
Biological Process	GO:0000165	MAPK cascade	MYC	IMP		Human	PMID:17873522
Biological Process	GO:0042474	middle ear morphogenesis	Myc	IMP	MGI:MGI:2178233,MGI:MGI:2386570	Mouse	PMID:17523175
Biological Process	GO:0051450	myoblast proliferation	Myc	IEP		Rat	PMID:2425941\|RGD:151667421
Biological Process	GO:0014902	myotube differentiation	Myc	IMP		Mouse	PMID:22147266
Biological Process	GO:0051782	negative regulation of cell division	MYC	IDA		Human	PMID:10962037
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	Myc	IMP		Rat	PMID:22100782\|RGD:7240569
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	MYC	IDA		Human	PMID:10962037
Biological Process	GO:0010629	negative regulation of gene expression	Myc	IMP		Rat	PMID:23349663\|RGD:7207857
Biological Process	GO:0046325	negative regulation of glucose import	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0045656	negative regulation of monocyte differentiation	MYC	IMP		Human	PMID:9924025
Biological Process	GO:0032091	negative regulation of protein binding	Myc	IDA		Mouse	PMID:18045875
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYC	IDA		Human	PMID:10412034
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYC	IDA		Human	PMID:18393360
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYC	IDA		Human	PMID:19160485
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYC	IMP		Human	PMID:19786833
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MYC	IDA		Human	PMID:9924025
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Myc	IDA		Mouse	PMID:12196193
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Myc	IMP		Rat	PMID:9924025\|RGD:8554663
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	mycb	IMP		Zfish	PMID:30606747
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	mycb	IDA		Zfish	PMID:30606747
Biological Process	GO:0001866	NK T cell proliferation	Myc	IMP	MGI:MGI:2178233	Mouse	PMID:19423665
Biological Process	GO:0001541	ovarian follicle development	Myc	IEP		Rat	PMID:9071960\|RGD:10059613
Biological Process	GO:0030728	ovulation	Myc	IEP		Rat	PMID:9071960\|RGD:10059613
Biological Process	GO:0043473	pigmentation	Myc	IMP	MGI:MGI:2178233,MGI:MGI:2386570	Mouse	PMID:17523175
Biological Process	GO:1904699	positive regulation of acinar cell proliferation	Myc	IGI	MGI:MGI:88039	Mouse	PMID:17596282
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Myc	IMP	MGI:MGI:2447604	Mouse	PMID:14517295
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Myc	IDA		Mouse	PMID:14517295
Biological Process	GO:2001171	positive regulation of ATP biosynthetic process	Myc	IMP		Rat	PMID:22629444\|RGD:7240532
Biological Process	GO:0002904	positive regulation of B cell apoptotic process	Myc	IGI	MGI:MGI:99702	Mouse	PMID:11604501
Biological Process	GO:0043085	positive regulation of catalytic activity	Myc	IMP		Mouse	PMID:17382917
Biological Process	GO:0045787	positive regulation of cell cycle	Myc	IMP		Rat	PMID:22210745\|RGD:7240565
Biological Process	GO:0008284	positive regulation of cell population proliferation	MYC	IDA		Human	PMID:15994933
Biological Process	GO:0008284	positive regulation of cell population proliferation	Myc	IDA		Mouse	PMID:14517295
Biological Process	GO:0008284	positive regulation of cell population proliferation	Myc	IDA		Mouse	PMID:12235125
Biological Process	GO:0008284	positive regulation of cell population proliferation	Myc	IGI	RGD:2328	Rat	PMID:21980073\|RGD:7241005
Biological Process	GO:1901857	positive regulation of cellular respiration	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	MYC	IDA		Human	PMID:19179467
Biological Process	GO:0043388	positive regulation of DNA binding	Myc	IMP		Rat	PMID:12873812\|RGD:10059626
Biological Process	GO:1905643	positive regulation of DNA methylation	MYC	IMP		Human	PMID:19786833
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MYC	IDA		Human	PMID:10962037
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MYC	IDA		Human	PMID:17558397
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MYC	IDA		Human	PMID:18818310
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MYC	IDA		Human	PMID:8425218
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myc	IDA		Mouse	MGI:MGI:5810267\|PMID:9637678
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myc	IDA		Mouse	MGI:MGI:4839428\|PMID:20434984
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myc	IDA		Rat	PMID:18818310\|RGD:8554535
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	MYC	IDA		Human	PMID:18987311
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	MYC	IMP		Human	PMID:15674325
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	MYC	IDA		Human	PMID:18987311
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	MYC	IDA		Human	PMID:9924025
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0010628	positive regulation of gene expression	MYC	IDA		Human	PMID:15459207
Biological Process	GO:0010628	positive regulation of gene expression	MYC	IGI	UniProtKB:Q01986	Human	PMID:15459207
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Myc	IMP		Rat	PMID:9316053\|RGD:10059624
Biological Process	GO:0045821	positive regulation of glycolytic process	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	MYC	IDA		Human	PMID:10962037
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Myc	IMP		Mouse	MGI:MGI:3830398\|PMID:19161241
Biological Process	GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	Myc	IMP		Mouse	MGI:MGI:3830398\|PMID:19161241
Biological Process	GO:1902895	positive regulation of miRNA transcription	MYC	IDA		Human	PMID:27791094
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	Myc	IMP		Rat	PMID:22629444\|RGD:7240532
Biological Process	GO:1903862	positive regulation of oxidative phosphorylation	Myc	IMP		Rat	PMID:18414044\|RGD:10059611
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Myc	IMP		Rat	PMID:8421701\|RGD:10059629
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Myc	IMP		Rat	PMID:8113414\|RGD:10059612
Biological Process	GO:0051973	positive regulation of telomerase activity	Myc	IMP		Mouse	MGI:MGI:5810267\|PMID:9637678
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYC	IDA		Human	PMID:10723141
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MYC	IMP		Human	PMID:9924025
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myc	IDA		Mouse	PMID:23277542
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myc	IMP		Mouse	PMID:17382917
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myc	IMP		Rat	PMID:12480946\|RGD:1581934
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	mycb	IMP		Zfish	PMID:30606747
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	mycb	IDA		Zfish	PMID:30606747
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	Myc	IDA		Mouse	MGI:MGI:6377809\|PMID:26691508
Biological Process	GO:0016485	protein processing	Myc	IMP	MGI:MGI:1931143	Mouse	PMID:12970677
Biological Process	GO:0032986	protein-DNA complex disassembly	MYC	IDA		Human	PMID:19160485
Biological Process	GO:0006848	pyruvate transport	Myc	IMP		Rat	PMID:22842522\|RGD:7207891
Biological Process	GO:0000320	re-entry into mitotic cell cycle	Myc	IMP		Rat	PMID:18414044\|RGD:10059611
Biological Process	GO:0042981	regulation of apoptotic process	Myc	IDA		Mouse	PMID:12235125
Biological Process	GO:0042981	regulation of apoptotic process	Myc	IMP		Mouse	PMID:23277542
Biological Process	GO:0010564	regulation of cell cycle process	MYC	IDA		Human	PMID:8782822
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IDA		Mouse	MGI:MGI:6323493\|PMID:31005419
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IGI	MGI:MGI:104987	Mouse	PMID:8521822
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IGI	MGI:MGI:104991	Mouse	PMID:8521822
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IGI	MGI:MGI:96921	Mouse	PMID:8521822
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IDA		Rat	PMID:11799123\|RGD:619701
Biological Process	GO:0006355	regulation of DNA-templated transcription	Myc	IMP		Rat	PMID:17341548\|RGD:2290581
Biological Process	GO:0010468	regulation of gene expression	MYC	IDA		Human	PMID:21447833
Biological Process	GO:0010468	regulation of gene expression	Myc	IDA		Mouse	PMID:11438662
Biological Process	GO:0007346	regulation of mitotic cell cycle	Myc	IMP		Rat	PMID:12070150\|RGD:625485
Biological Process	GO:0002082	regulation of oxidative phosphorylation	Myc	IMP		Rat	PMID:22629444\|RGD:7240532
Biological Process	GO:1904672	regulation of somatic stem cell population maintenance	Myc	IDA		Mouse	MGI:MGI:6323493\|PMID:31005419
Biological Process	GO:0032204	regulation of telomere maintenance	MYC	IMP		Human	PMID:17765874
Biological Process	GO:1901342	regulation of vasculature development	myca	IGI	ZFIN:ZDB-MRPHLNO-090709-1,ZFIN:ZDB-MRPHLNO-180118-2	Zfish	PMID:24940000
Biological Process	GO:0043279	response to alkaloid	Myc	IMP	MGI:MGI:1931143	Mouse	PMID:12970677
Biological Process	GO:0032355	response to estradiol	Myc	IEP		Rat	PMID:23027806\|RGD:7207887
Biological Process	GO:0045471	response to ethanol	Myc	IEP		Rat	PMID:12370848\|RGD:10059625
Biological Process	GO:0010332	response to gamma radiation	MYC	IDA		Human	PMID:19179467
Biological Process	GO:0044752	response to human chorionic gonadotropin	Myc	IEP		Rat	PMID:9071960\|RGD:10059613
Biological Process	GO:0009314	response to radiation	Myc	IMP	MGI:MGI:2447604	Mouse	PMID:14517295
Biological Process	GO:0009314	response to radiation	Myc	IDA		Mouse	PMID:14517295
Biological Process	GO:0009611	response to wounding	Myc	IEP		Rat	PMID:20694826\|RGD:7240697
Biological Process	GO:0009410	response to xenobiotic stimulus	MYC	IEP		Human	PMID:18291362
Biological Process	GO:0035914	skeletal muscle cell differentiation	Myc	IMP		Mouse	PMID:22147266
Biological Process	GO:0048705	skeletal system morphogenesis	Myc	IMP	MGI:MGI:2178233,MGI:MGI:2386570	Mouse	PMID:17523175
Biological Process	GO:0042246	tissue regeneration	mycb	IDA		Zfish	PMID:30606747
Biological Process	GO:0042246	tissue regeneration	mycb	IMP		Zfish	PMID:30606747
Biological Process	GO:0006366	transcription by RNA polymerase II	Myc	IMP		Mouse	PMID:17382917
Biological Process	GO:0006366	transcription by RNA polymerase II	Myc	IDA		Rat	PMID:15139290\|RGD:1601462
Biological Process	GO:0001944	vasculature development	myca	IMP	ZFIN:ZDB-MRPHLNO-180118-2	Zfish	PMID:24940000
Biological Process	GO:0016055	Wnt signaling pathway	Myc	IDA		Mouse	PMID:19056892

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.