Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myh10

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYH10
- Mouse genes Myh10
- Rat genes Myh10
- Zfish genes myh10
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myh10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	MYH10	IMP		Human	PMID:24072716
Molecular Function	GO:0051015	actin filament binding	MYH10	IDA		Human	PMID:15845534
Molecular Function	GO:0043531	ADP binding	MYH10	IDA		Human	PMID:15845534
Molecular Function	GO:0005524	ATP binding	MYH10	IDA		Human	PMID:15845534
Molecular Function	GO:0042802	identical protein binding	Myh10	IDA		Rat	PMID:25131674\|RGD:12798516
Molecular Function	GO:0000146	microfilament motor activity	MYH10	IMP		Human	PMID:24072716
Molecular Function	GO:0000146	microfilament motor activity	MYH10	IDA		Human	PMID:15845534
Molecular Function	GO:0048027	mRNA 5'-UTR binding	MYH10	IDA		Human	PMID:20603131
Molecular Function	GO:0005515	protein binding	MYH10	IPI	UniProtKB:Q9BRS8	Human	PMID:20603131
Molecular Function	GO:0005515	protein binding	MYH10	IPI	UniProtKB:Q15334	Human	PMID:7542763
Molecular Function	GO:0005515	protein binding	Myh10	IPI	UniProtKB:Q7TNC6	Mouse	MGI:MGI:4454194\|PMID:20439720
Molecular Function	GO:0005515	protein binding	Myh10	IPI	UniProtKB:Q13286	Mouse	MGI:MGI:4880602\|PMID:20850431
Molecular Function	GO:0005515	protein binding	Myh10	IPI	UniProtKB:P40424	Mouse	PMID:12724421
Molecular Function	GO:0005515	protein binding	Myh10	IPI	PR:Q9QVP4	Mouse	PMID:15663482
Molecular Function	GO:0005515	protein binding	Myh10	IPI	RGD:620028	Rat	PMID:20479336\|RGD:2325835
Molecular Function	GO:0035613	RNA stem-loop binding	MYH10	IDA		Human	PMID:20603131
Cellular Component	GO:0042641	actomyosin	MYH10	IDA		Human	PMID:24072716
Cellular Component	GO:0030424	axon	Myh10	IDA		Mouse	PMID:15880105
Cellular Component	GO:0005903	brush border	Myh10	IDA		Mouse	MGI:MGI:5621262\|PMID:22114352
Cellular Component	GO:0005938	cell cortex	MYH10	IDA		Human	PMID:7699007
Cellular Component	GO:0005938	cell cortex	Myh10	IDA		Mouse	PMID:8482409
Cellular Component	GO:0005938	cell cortex	Myh10	IDA		Mouse	PMID:9725909
Cellular Component	GO:0032154	cleavage furrow	MYH10	IDA		Human	PMID:11029059
Cellular Component	GO:0032154	cleavage furrow	MYH10	IDA		Human	PMID:7699007
Cellular Component	GO:0005737	cytoplasm	MYH10	IDA		Human	PMID:7699007
Cellular Component	GO:0005737	cytoplasm	Myh10	IDA		Mouse	PMID:8482409
Cellular Component	GO:0005737	cytoplasm	Myh10	IDA		Mouse	PMID:15177565
Cellular Component	GO:0005737	cytoplasm	Myh10	IDA		Mouse	PMID:12724421
Cellular Component	GO:0005737	cytoplasm	Myh10	IDA		Mouse	PMID:16895968
Cellular Component	GO:0005737	cytoplasm	Myh10	IDA		Mouse	PMID:9725909
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Myh10	IDA		Mouse	PMID:16895968
Cellular Component	GO:0005829	cytosol	MYH10	IMP		Human	PMID:20603131
Cellular Component	GO:0043197	dendritic spine	Myh10	IDA		Mouse	PMID:16481398
Cellular Component	GO:0070062	extracellular exosome	MYH10	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Myh10	IMP		Mouse	PMID:25220605
Cellular Component	GO:0098978	glutamatergic synapse	Myh10	IDA		Mouse	PMID:25220605
Cellular Component	GO:0098978	glutamatergic synapse	Myh10	IDA		Rat	PMID:19889835\|RGD:13702455
Cellular Component	GO:0098978	glutamatergic synapse	Myh10	IDA		Rat	PMID:20797537\|RGD:12050124
Cellular Component	GO:0098978	glutamatergic synapse	Myh10	IMP		Rat	PMID:20797537\|RGD:12050124
Cellular Component	GO:0030426	growth cone	Myh10	IDA		Mouse	PMID:15880105
Cellular Component	GO:0030027	lamellipodium	Myh10	IDA		Rat	PMID:25131674\|RGD:12798516
Cellular Component	GO:0030496	midbody	MYH10	IDA		Human	PMID:11029059
Cellular Component	GO:0016459	myosin complex	Myh10	IDA		Mouse	PMID:8482409
Cellular Component	GO:0016459	myosin complex	Myh10	IDA		Mouse	PMID:9356462
Cellular Component	GO:0016459	myosin complex	Myh10	IDA		Mouse	PMID:9725909
Cellular Component	GO:0016460	myosin II complex	MYH10	IDA		Human	PMID:24072716
Cellular Component	GO:0016460	myosin II complex	Myh10	IDA		Mouse	PMID:21126233
Cellular Component	GO:0097513	myosin II filament	MYH10	IDA		Human	PMID:24072716
Cellular Component	GO:0031594	neuromuscular junction	Myh10	IDA		Mouse	PMID:16012337
Cellular Component	GO:0043005	neuron projection	Myh10	IDA		Mouse	PMID:16481398
Cellular Component	GO:0043025	neuronal cell body	Myh10	IDA		Mouse	PMID:16481398
Cellular Component	GO:0005634	nucleus	MYH10	HDA		Human	PMID:21630459
Cellular Component	GO:0005844	polysome	MYH10	IMP		Human	PMID:20603131
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myh10	IDA		Rat	PMID:19889835\|RGD:13702455
Cellular Component	GO:0016528	sarcoplasm	Myh10	IDA		Mouse	PMID:12893741
Cellular Component	GO:0005819	spindle	Myh10	IDA		Mouse	PMID:9725909
Cellular Component	GO:0001725	stress fiber	MYH10	IDA		Human	PMID:15774463
Cellular Component	GO:0001725	stress fiber	MYH10	IDA		Human	PMID:7699007
Cellular Component	GO:0001725	stress fiber	Myh10	IDA		Mouse	PMID:12893741
Cellular Component	GO:0001725	stress fiber	Myh10	IMP		Mouse	PMID:14617807
Cellular Component	GO:0001725	stress fiber	Myh10	IDA		Mouse	PMID:14699073
Biological Process	GO:0030036	actin cytoskeleton organization	Myh10	IGI	MGI:MGI:1351655	Mouse	PMID:16249236
Biological Process	GO:0030036	actin cytoskeleton organization	Myh10	IGI	MGI:MGI:107927	Mouse	PMID:16249236
Biological Process	GO:0051017	actin filament bundle assembly	Myh10	IMP		Rat	PMID:22992457\|RGD:12798526
Biological Process	GO:0070650	actin filament bundle distribution	Myh10	IMP		Rat	PMID:22992457\|RGD:12798526
Biological Process	GO:0070650	actin filament bundle distribution	myh10	IMP	ZFIN:ZDB-MRPHLNO-150309-6	Zfish	PMID:25446029
Biological Process	GO:0030048	actin filament-based movement	MYH10	IDA		Human	PMID:15845534
Biological Process	GO:0031032	actomyosin structure organization	MYH10	IMP		Human	PMID:24072716
Biological Process	GO:0007512	adult heart development	Myh10	IMP	MGI:MGI:3052104	Mouse	PMID:12893741
Biological Process	GO:0007512	adult heart development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:12893741
Biological Process	GO:0007512	adult heart development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:10712438
Biological Process	GO:0007512	adult heart development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:9356462
Biological Process	GO:0007512	adult heart development	Myh10	IMP	MGI:MGI:2386439	Mouse	PMID:10712438
Biological Process	GO:0035904	aorta development	Myh10	IMP		Mouse	PMID:25807483
Biological Process	GO:0007411	axon guidance	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:15880105
Biological Process	GO:0007409	axonogenesis	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0007420	brain development	Myh10	IMP	MGI:MGI:3664764	Mouse	PMID:16481398
Biological Process	GO:0007420	brain development	Myh10	IMP	MGI:MGI:3664765	Mouse	PMID:16481398
Biological Process	GO:0007420	brain development	Myh10	IEP		Rat	PMID:10334910\|RGD:633431
Biological Process	GO:0060038	cardiac muscle cell proliferation	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:12893741
Biological Process	GO:0055003	cardiac myofibril assembly	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:9356462
Biological Process	GO:0003279	cardiac septum development	Myh10	IMP		Mouse	PMID:25807483
Biological Process	GO:0007155	cell adhesion	Myh10	IDA		Rat	PMID:24042022\|RGD:12879829
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Myh10	IMP	MGI:MGI:3664765	Mouse	PMID:16481398
Biological Process	GO:0060976	coronary vasculature development	Myh10	IMP		Mouse	PMID:25807483
Biological Process	GO:0006887	exocytosis	Myh10	IMP		Mouse	PMID:14617807
Biological Process	GO:0021592	fourth ventricle development	Myh10	IMP	MGI:MGI:3664764	Mouse	PMID:16481398
Biological Process	GO:0021592	fourth ventricle development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0007507	heart development	Myh10	IMP		Mouse	PMID:25807483
Biological Process	GO:0001701	in utero embryonic development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0001701	in utero embryonic development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:12893741
Biological Process	GO:0001701	in utero embryonic development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:9356462
Biological Process	GO:0001701	in utero embryonic development	Myh10	IMP	MGI:MGI:3052104	Mouse	PMID:12893741
Biological Process	GO:0021670	lateral ventricle development	Myh10	IMP	MGI:MGI:2386439	Mouse	PMID:10712438
Biological Process	GO:0021670	lateral ventricle development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0021670	lateral ventricle development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:9356462
Biological Process	GO:0021555	midbrain-hindbrain boundary morphogenesis	myh10	IMP	ZFIN:ZDB-MRPHLNO-150309-6	Zfish	PMID:25446029
Biological Process	GO:0000281	mitotic cytokinesis	MYH10	IDA		Human	PMID:15774463
Biological Process	GO:0000281	mitotic cytokinesis	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:12893741
Biological Process	GO:0000281	mitotic cytokinesis	Myh10	IMP	MGI:MGI:3052104	Mouse	PMID:12893741
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Myh10	IMP		Rat	PMID:20797537\|RGD:12050124
Biological Process	GO:0030239	myofibril assembly	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:10712438
Biological Process	GO:0030239	myofibril assembly	Myh10	IMP	MGI:MGI:2386439	Mouse	PMID:10712438
Biological Process	GO:0050885	neuromuscular process controlling balance	Myh10	IMP	MGI:MGI:3664765	Mouse	PMID:16481398
Biological Process	GO:0001764	neuron migration	Myh10	IMP	MGI:MGI:3052104	Mouse	PMID:15034141
Biological Process	GO:0001764	neuron migration	Myh10	IMP	MGI:MGI:2386439	Mouse	PMID:10712438
Biological Process	GO:0001764	neuron migration	Myh10	IMP	MGI:MGI:3664764	Mouse	PMID:16481398
Biological Process	GO:0001764	neuron migration	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0031175	neuron projection development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:15880105
Biological Process	GO:0007097	nuclear migration	Myh10	IMP		Mouse	PMID:16895968
Biological Process	GO:0001778	plasma membrane repair	Myh10	IMP		Mouse	PMID:14617807
Biological Process	GO:0050714	positive regulation of protein secretion	MYH10	IMP		Human	PMID:20603131
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Myh10	IDA		Mouse	PMID:25220605
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Myh10	IMP		Mouse	PMID:25220605
Biological Process	GO:0008360	regulation of cell shape	Myh10	IMP		Mouse	PMID:16895968
Biological Process	GO:0008360	regulation of cell shape	myh10	IMP	ZFIN:ZDB-MRPHLNO-150309-6	Zfish	PMID:25446029
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Myh10	IDA		Rat	PMID:20797537\|RGD:12050124
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Myh10	IMP		Rat	PMID:20797537\|RGD:12050124
Biological Process	GO:0060041	retina development in camera-type eye	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0060041	retina development in camera-type eye	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:9356462
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:14699073
Biological Process	GO:0021678	third ventricle development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:11283949
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Myh10	IMP	MGI:MGI:3052104	Mouse	PMID:12893741
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Myh10	IMP	MGI:MGI:2386445	Mouse	PMID:12893741

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.