Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYH2
  • Mouse genes Myh2
  • Rat genes
  • Zfish genes myha,myhb,myhc4,myhz1.1,myhz1.2,myhz1.3,myhz2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MYH2	IPI	UniProtKB:Q8N6F7	Human	PMID:17823310
Cellular Component	GO:0031672	A band	Myh2	IDA		Mouse	PMID:18761673
Cellular Component	GO:0005826	actomyosin contractile ring	Myh2	IDA		Mouse	PMID:15548599
Cellular Component	GO:0005911	cell-cell junction	MYH2	IMP		Human	PMID:25753039
Cellular Component	GO:0005911	cell-cell junction	Myh2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0005794	Golgi apparatus	Myh2	IMP		Mouse	PMID:14617807
Cellular Component	GO:0030016	myofibril	MYH2	IDA		Human	PMID:8145163
Cellular Component	GO:0030016	myofibril	Myh2	IDA		Mouse	PMID:21884692
Cellular Component	GO:0032991	protein-containing complex	MYH2	IDA		Human	GO_REF:0000054
Biological Process	GO:0070252	actin-mediated cell contraction	Myh2	IDA		Mouse	PMID:22750946
Biological Process	GO:0048706	embryonic skeletal system development	myhz2	IMP	ZFIN:ZDB-GENO-180503-11	Zfish	PMID:28835471
Biological Process	GO:0006936	muscle contraction	MYH2	IDA		Human	PMID:8145163
Biological Process	GO:0001778	plasma membrane repair	Myh2	IMP		Mouse	PMID:14617807
Biological Process	GO:0014823	response to activity	Myh2	IDA		Mouse	PMID:18310078
Biological Process	GO:0014823	response to activity	myhz2	IDA		Zfish	PMID:16966387
Biological Process	GO:0048741	skeletal muscle fiber development	myhz2	IMP	ZFIN:ZDB-MRPHLNO-140619-4	Zfish	PMID:24523292
Biological Process	GO:0001501	skeletal system development	myhz2	IMP	ZFIN:ZDB-GENO-180503-11	Zfish	PMID:28835471
Biological Process	GO:0001757	somite specification	myhz1.1	IEP		Zfish	PMID:11002340

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern