Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYH9
  • Mouse genes Myh9
  • Rat genes Myh9
  • Zfish genes myh9b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myh9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	MYH9	IDA		Human	PMID:15065866
Molecular Function	GO:0051015	actin filament binding	MYH9	IDA		Human	PMID:24072716
Molecular Function	GO:0051015	actin filament binding	MYH9	IDA		Human	PMID:12237319
Molecular Function	GO:0051015	actin filament binding	MYH9	IDA		Human	PMID:14508515
Molecular Function	GO:0051015	actin filament binding	MYH9	IDA		Human	PMID:15845534
Molecular Function	GO:0043531	ADP binding	MYH9	IDA		Human	PMID:15065866
Molecular Function	GO:0005524	ATP binding	MYH9	IDA		Human	PMID:15065866
Molecular Function	GO:0005524	ATP binding	MYH9	IDA		Human	PMID:15845534
Molecular Function	GO:0045296	cadherin binding	MYH9	HDA		Human	PMID:25468996
Molecular Function	GO:0031762	follicle-stimulating hormone receptor binding	Myh9	IDA		Rat	PMID:20068007|RGD:6902910
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Myh9	IDA		Rat	PMID:20068007|RGD:6902910
Molecular Function	GO:0042802	identical protein binding	MYH9	IPI	UniProtKB:P35579	Human	PMID:22483112
Molecular Function	GO:0042802	identical protein binding	MYH9	IPI	UniProtKB:P35579	Human	PMID:31837246
Molecular Function	GO:0042802	identical protein binding	Myh9	IDA		Rat	PMID:25131674|RGD:12798516
Molecular Function	GO:0005178	integrin binding	MYH9	IDA		Human	PMID:10822899
Molecular Function	GO:0000146	microfilament motor activity	MYH9	IDA		Human	PMID:24072716
Molecular Function	GO:0000146	microfilament motor activity	MYH9	IDA		Human	PMID:12237319
Molecular Function	GO:0000146	microfilament motor activity	MYH9	IDA		Human	PMID:15845534
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P05106	Human	PMID:10822899
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:Q05397	Human	PMID:10822899
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:O46385	Human	PMID:12202484
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P51681	Human	PMID:12421915
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P61073	Human	PMID:12421915
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P62993	Human	PMID:12577067
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:O00255	Human	PMID:14508515
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:O00255-2	Human	PMID:14508515
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:14640694
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P25815	Human	PMID:15171681
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:15479433
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:Q86VB7	Human	PMID:15479433
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P12821-1	Human	PMID:16186248
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P19338	Human	PMID:16403913
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:O46385	Human	PMID:17925381
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:Q969F2	Human	PMID:18504258
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:20421509
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:Q9BRS8	Human	PMID:20603131
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P83110	Human	PMID:22229724
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:22460785
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:22483112
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:O75132	Human	PMID:22693546
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P31146	Human	PMID:23100250
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P62993	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P20336	Human	PMID:2732579
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P20336	Human	PMID:27325790
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:Q9UPQ0	Human	PMID:28228547
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P04271	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P06703	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P23297	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P25815	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P26447	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P29034	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P33763	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	MYH9	IPI	UniProtKB:P0DTC2	Human	PMID:34873039
Molecular Function	GO:0005515	protein binding	Myh9	IPI	UniProtKB:Q923J1	Mouse	MGI:MGI:5644004|PMID:24855944
Molecular Function	GO:0005515	protein binding	Myh9	IPI	UniProtKB:Q3U0S6	Mouse	MGI:MGI:5052000|PMID:21396893
Molecular Function	GO:0005515	protein binding	Myh9	IPI	PR:Q923J1	Mouse	PMID:16407977
Molecular Function	GO:0005515	protein binding	Myh9	IPI	RGD:1359203	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0005515	protein binding	Myh9	IPI	RGD:621007	Rat	PMID:19340093|RGD:6902911
Molecular Function	GO:0005515	protein binding	Myh9	IPI	RGD:68407	Rat	PMID:19340093|RGD:6902911
Molecular Function	GO:0019904	protein domain specific binding	MYH9	IPI	UniProtKB:P06396	Human	PMID:23325791
Molecular Function	GO:0019904	protein domain specific binding	Myh9	IPI	UniProtKB:P06396	Mouse	MGI:MGI:5619440|PMID:23325791
Molecular Function	GO:0042803	protein homodimerization activity	MYH9	IDA		Human	PMID:12237319
Molecular Function	GO:0019901	protein kinase binding	Myh9	IPI	RGD:69283	Rat	PMID:19117932|RGD:6902913
Molecular Function	GO:0043495	protein-membrane adaptor activity	MYH9	IMP		Human	PMID:16403913
Molecular Function	GO:0003723	RNA binding	MYH9	HDA		Human	PMID:22681889
Molecular Function	GO:0097110	scaffold protein binding	Myh9	IDA		Rat	PMID:21598299|RGD:12798522
Cellular Component	GO:0015629	actin cytoskeleton	MYH9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015629	actin cytoskeleton	MYH9	IDA		Human	PMID:15869600
Cellular Component	GO:0005884	actin filament	Myh9	IDA		Rat	PMID:21598299|RGD:12798522
Cellular Component	GO:0042641	actomyosin	MYH9	IDA		Human	PMID:24072716
Cellular Component	GO:0005826	actomyosin contractile ring	MYH9	IDA		Human	PMID:11029059
Cellular Component	GO:0005912	adherens junction	Myh9	IDA		Mouse	PMID:15292239
Cellular Component	GO:0016324	apical plasma membrane	Myh9	IDA		Rat	PMID:24042022|RGD:12879829
Cellular Component	GO:0005903	brush border	Myh9	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005903	brush border	Myh9	IDA		Rat	PMID:22357915|RGD:7243154
Cellular Component	GO:0005938	cell cortex	Myh9	IDA		Mouse	MGI:MGI:6323780|PMID:31118423
Cellular Component	GO:0005938	cell cortex	Myh9	IDA		Mouse	PMID:16895968
Cellular Component	GO:0005938	cell cortex	Myh9	IDA		Mouse	PMID:9725909
Cellular Component	GO:0031252	cell leading edge	MYH9	IDA		Human	PMID:12421915
Cellular Component	GO:0032154	cleavage furrow	MYH9	IDA		Human	PMID:14508515
Cellular Component	GO:0032154	cleavage furrow	MYH9	IDA		Human	PMID:7699007
Cellular Component	GO:0030863	cortical cytoskeleton	Myh9	IDA		Mouse	PMID:12893741
Cellular Component	GO:0060473	cortical granule	Myh9	IDA		Mouse	MGI:MGI:6323780|PMID:31118423
Cellular Component	GO:0005737	cytoplasm	MYH9	IDA		Human	PMID:22693546
Cellular Component	GO:0005737	cytoplasm	MYH9	IDA		Human	PMID:7699007
Cellular Component	GO:0005737	cytoplasm	Myh9	IDA		Mouse	PMID:15555549
Cellular Component	GO:0005737	cytoplasm	Myh9	IDA		Mouse	PMID:15177565
Cellular Component	GO:0005737	cytoplasm	Myh9	IDA		Mouse	PMID:15292239
Cellular Component	GO:0005737	cytoplasm	Myh9	IDA		Mouse	PMID:9725909
Cellular Component	GO:0005737	cytoplasm	Myh9	IDA		Rat	PMID:19117932|RGD:6902913
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	MYH9	IDA		Human	PMID:15064761
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Myh9	IDA		Mouse	PMID:16895968
Cellular Component	GO:0005829	cytosol	MYH9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	MYH9	IDA		Human	PMID:14508515
Cellular Component	GO:0005768	endosome	Myh9	IDA		Rat	PMID:19340093|RGD:6902911
Cellular Component	GO:0070062	extracellular exosome	MYH9	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MYH9	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	MYH9	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	MYH9	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	MYH9	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	Myh9	IDA		Mouse	MGI:MGI:5619440|PMID:23325791
Cellular Component	GO:0001772	immunological synapse	MYH9	IDA		Human	PMID:15064761
Cellular Component	GO:0001772	immunological synapse	Myh9	IDA		Mouse	PMID:15064761
Cellular Component	GO:0030027	lamellipodium	Myh9	IDA		Rat	PMID:25131674|RGD:12798516
Cellular Component	GO:0016328	lateral plasma membrane	Myh9	IDA		Rat	PMID:19117932|RGD:6902913
Cellular Component	GO:0016020	membrane	MYH9	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Myh9	IDA		Rat	PMID:21398640|RGD:12879877
Cellular Component	GO:0016459	myosin complex	Myh9	IDA		Mouse	PMID:8482409
Cellular Component	GO:0016459	myosin complex	Myh9	IDA		Mouse	PMID:9356462
Cellular Component	GO:0016459	myosin complex	Myh9	IDA		Mouse	PMID:9725909
Cellular Component	GO:0016460	myosin II complex	MYH9	IDA		Human	PMID:24072716
Cellular Component	GO:0016460	myosin II complex	Myh9	IDA		Mouse	PMID:21126233
Cellular Component	GO:0097513	myosin II filament	MYH9	IDA		Human	PMID:24072716
Cellular Component	GO:0031594	neuromuscular junction	Myh9	IDA		Mouse	PMID:16012337
Cellular Component	GO:0016604	nuclear body	MYH9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MYH9	IDA		Human	PMID:14508515
Cellular Component	GO:0045335	phagocytic vesicle	Myh9	IDA		Rat	PMID:19117932|RGD:6902913
Cellular Component	GO:0005886	plasma membrane	MYH9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MYH9	IDA		Human	PMID:16186248
Cellular Component	GO:0005886	plasma membrane	MYH9	IDA		Human	PMID:16403913
Cellular Component	GO:0032991	protein-containing complex	MYH9	IDA		Human	PMID:12421915
Cellular Component	GO:0032991	protein-containing complex	Myh9	IDA		Rat	PMID:15823548|RGD:1600561
Cellular Component	GO:0001726	ruffle	MYH9	IDA		Human	PMID:16403913
Cellular Component	GO:0005819	spindle	Myh9	IDA		Mouse	PMID:9725909
Cellular Component	GO:0001725	stress fiber	MYH9	IDA		Human	PMID:14508515
Cellular Component	GO:0001725	stress fiber	MYH9	IDA		Human	PMID:14706930
Cellular Component	GO:0001725	stress fiber	MYH9	IDA		Human	PMID:15774463
Cellular Component	GO:0001725	stress fiber	MYH9	IDA		Human	PMID:16403913
Cellular Component	GO:0001725	stress fiber	MYH9	IDA		Human	PMID:7699007
Cellular Component	GO:0001725	stress fiber	Myh9	IDA		Mouse	PMID:16895968
Cellular Component	GO:0001931	uropod	MYH9	IDA		Human	PMID:15064761
Cellular Component	GO:0001931	uropod	Myh9	IDA		Mouse	PMID:15064761
Biological Process	GO:0031532	actin cytoskeleton reorganization	MYH9	IMP		Human	PMID:15869600
Biological Process	GO:0031532	actin cytoskeleton reorganization	Myh9	IMP		Rat	PMID:23354122|RGD:12798521
Biological Process	GO:0051017	actin filament bundle assembly	Myh9	IMP		Rat	PMID:22992457|RGD:12798526
Biological Process	GO:0070650	actin filament bundle distribution	Myh9	IMP		Rat	PMID:22992457|RGD:12798526
Biological Process	GO:0070650	actin filament bundle distribution	myh9b	IMP	ZFIN:ZDB-MRPHLNO-150309-4	Zfish	PMID:25446029
Biological Process	GO:0030048	actin filament-based movement	MYH9	IDA		Human	PMID:15845534
Biological Process	GO:0030048	actin filament-based movement	MYH9	IDA		Human	PMID:12237319
Biological Process	GO:0031032	actomyosin structure organization	MYH9	IDA		Human	PMID:24072716
Biological Process	GO:0001525	angiogenesis	MYH9	IDA		Human	PMID:16403913
Biological Process	GO:0043534	blood vessel endothelial cell migration	MYH9	IMP		Human	PMID:16403913
Biological Process	GO:0007155	cell adhesion	Myh9	IMP		Mouse	PMID:16407977
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	Myh9	IMP	MGI:MGI:3522434	Mouse	PMID:15292239
Biological Process	GO:0098609	cell-cell adhesion	Myh9	IMP	MGI:MGI:3522434	Mouse	PMID:15292239
Biological Process	GO:0098609	cell-cell adhesion	Myh9	IMP		Rat	PMID:21598299|RGD:12798522
Biological Process	GO:0071260	cellular response to mechanical stimulus	Myh9	IEP		Rat	PMID:8888698|RGD:11533927
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Myh9	IEP		Rat	PMID:8888698|RGD:11533927
Biological Process	GO:0060471	cortical granule exocytosis	Myh9	IMP		Mouse	MGI:MGI:6323780|PMID:31118423
Biological Process	GO:0032506	cytokinetic process	MYH9	IMP		Human	PMID:15774463
Biological Process	GO:0051295	establishment of meiotic spindle localization	Myh9	IDA		Mouse	PMID:9725909
Biological Process	GO:0001768	establishment of T cell polarity	Myh9	IMP		Mouse	PMID:15064761
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Myh9	IMP		Rat	PMID:20068007|RGD:6902910
Biological Process	GO:0001701	in utero embryonic development	Myh9	IMP	MGI:MGI:3511350	Mouse	PMID:15555549
Biological Process	GO:0001701	in utero embryonic development	Myh9	IMP	MGI:MGI:3641195	Mouse	PMID:16630581
Biological Process	GO:0032418	lysosome localization	MYH9	IMP		Human	PMID:2732579
Biological Process	GO:0000212	meiotic spindle organization	Myh9	IDA		Mouse	PMID:9725909
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	MYH9	IDA		Human	PMID:16186248
Biological Process	GO:0021555	midbrain-hindbrain boundary morphogenesis	myh9b	IMP	ZFIN:ZDB-MRPHLNO-150309-4	Zfish	PMID:25446029
Biological Process	GO:0030224	monocyte differentiation	MYH9	IEP		Human	PMID:1912569
Biological Process	GO:0007520	myoblast fusion	Myh9	IMP		Mouse	PMID:16895968
Biological Process	GO:1903919	negative regulation of actin filament severing	MYH9	IMP		Human	PMID:23325791
Biological Process	GO:1903919	negative regulation of actin filament severing	Myh9	IMP		Mouse	MGI:MGI:5619440|PMID:23325791
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	Myh9	IMP		Rat	PMID:21598299|RGD:12798522
Biological Process	GO:0006911	phagocytosis, engulfment	Myh9	IMP		Mouse	MGI:MGI:5619440|PMID:23325791
Biological Process	GO:0001778	plasma membrane repair	MYH9	IDA		Human	PMID:27325790
Biological Process	GO:0070527	platelet aggregation	MYH9	HMP		Human	PMID:23382103
Biological Process	GO:0030220	platelet formation	MYH9	IMP		Human	PMID:12237319
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	Myh9	IMP		Rat	PMID:20068007|RGD:6902910
Biological Process	GO:0045807	positive regulation of endocytosis	Myh9	IMP		Rat	PMID:19340093|RGD:6902911
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Myh9	IMP		Rat	PMID:23354122|RGD:12798521
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Myh9	IMP		Rat	PMID:21598299|RGD:12798522
Biological Process	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	Myh9	IMP		Rat	PMID:20068007|RGD:6902910
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	Myh9	IMP		Rat	PMID:20068007|RGD:6902910
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Myh9	IMP		Rat	PMID:23354122|RGD:12798521
Biological Process	GO:0050766	positive regulation of phagocytosis	Myh9	IMP		Rat	PMID:19117932|RGD:6902913
Biological Process	GO:1903923	positive regulation of protein processing in phagocytic vesicle	Myh9	IMP		Mouse	MGI:MGI:5619440|PMID:23325791
Biological Process	GO:0015031	protein transport	MYH9	IMP		Human	PMID:16403913
Biological Process	GO:0045055	regulated exocytosis	MYH9	IMP		Human	PMID:2732579
Biological Process	GO:0008360	regulation of cell shape	MYH9	IMP		Human	PMID:11029059
Biological Process	GO:0008360	regulation of cell shape	Myh9	IMP		Mouse	PMID:16895968
Biological Process	GO:0008360	regulation of cell shape	myh9b	IMP	ZFIN:ZDB-MRPHLNO-150309-4	Zfish	PMID:25446029
Biological Process	GO:1905684	regulation of plasma membrane repair	MYH9	IMP		Human	PMID:2732579
Biological Process	GO:0032796	uropod organization	Myh9	IMP		Mouse	PMID:15064761

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern