Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO1A
  • Mouse genes Myo1a
  • Rat genes Myo1a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Myo1a	IDA		Mouse	MGI:MGI:5607232|PMID:20089841
Molecular Function	GO:0005515	protein binding	Myo1a	IPI	RGD:3675	Rat	PMID:15138292|RGD:1581729
Cellular Component	GO:0015629	actin cytoskeleton	Myo1a	IDA		Rat	PMID:8635202|RGD:1581725
Cellular Component	GO:0016324	apical plasma membrane	Myo1a	IDA		Mouse	PMID:9933937
Cellular Component	GO:0009925	basal plasma membrane	Myo1a	IDA		Mouse	PMID:9933937
Cellular Component	GO:0016323	basolateral plasma membrane	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0005903	brush border	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0005903	brush border	Myo1a	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005903	brush border	Myo1a	IDA		Mouse	MGI:MGI:5607232|PMID:20089841
Cellular Component	GO:0005903	brush border	Myo1a	IDA		Mouse	PMID:15758024
Cellular Component	GO:0005903	brush border	Myo1a	IDA		Rat	PMID:15138292|RGD:1581729
Cellular Component	GO:0031252	cell leading edge	Myo1a	IDA		Rat	PMID:8635202|RGD:1581725
Cellular Component	GO:0030864	cortical actin cytoskeleton	MYO1A	IDA		Human	PMID:8692943
Cellular Component	GO:0005737	cytoplasm	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0031941	filamentous actin	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0030426	growth cone	Myo1a	IDA		Rat	PMID:8635202|RGD:1581725
Cellular Component	GO:0016328	lateral plasma membrane	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0016328	lateral plasma membrane	Myo1a	IDA		Mouse	PMID:9933937
Cellular Component	GO:0045121	membrane raft	Myo1a	IDA		Rat	PMID:15138292|RGD:1581729
Cellular Component	GO:0005902	microvillus	MYO1A	IDA		Human	PMID:9858156
Cellular Component	GO:0005902	microvillus	Myo1a	IDA		Mouse	PMID:9933937
Cellular Component	GO:0043005	neuron projection	Myo1a	IDA		Rat	PMID:8635202|RGD:1581725
Cellular Component	GO:0043025	neuronal cell body	Myo1a	IDA		Rat	PMID:8635202|RGD:1581725
Cellular Component	GO:0044853	plasma membrane raft	Myo1a	IDA		Mouse	MGI:MGI:5607232|PMID:20089841
Biological Process	GO:0030030	cell projection organization	Myo1a	IMP	MGI:MGI:3587749	Mouse	PMID:15758024
Biological Process	GO:0030033	microvillus assembly	Myo1a	IMP	MGI:MGI:3587749	Mouse	PMID:15758024
Biological Process	GO:0032880	regulation of protein localization	Myo1a	IMP		Rat	PMID:15138292|RGD:1581729
Biological Process	GO:0007605	sensory perception of sound	MYO1A	IMP		Human	PMID:12736868
Biological Process	GO:0051648	vesicle localization	MYO1A	IMP		Human	PMID:8692943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern