Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO1B
  • Mouse genes Myo1b
  • Rat genes Myo1b
  • Zfish genes myo1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Myo1b	IDA		Rat	PMID:20080738|RGD:8554448
Molecular Function	GO:0051015	actin filament binding	MYO1B	IMP		Human	PMID:21666684
Molecular Function	GO:0051015	actin filament binding	Myo1b	IDA		Rat	PMID:15647165|RGD:11532774
Molecular Function	GO:0005524	ATP binding	MYO1B	IMP		Human	PMID:21666684
Molecular Function	GO:0005524	ATP binding	Myo1b	IDA		Rat	PMID:17298083|RGD:8554192
Molecular Function	GO:0005524	ATP binding	Myo1b	IDA		Rat	PMID:20080738|RGD:8554448
Molecular Function	GO:0045296	cadherin binding	MYO1B	HDA		Human	PMID:25468996
Molecular Function	GO:0005516	calmodulin binding	Myo1b	IDA		Rat	PMID:16254000|RGD:8554605
Molecular Function	GO:0003774	cytoskeletal motor activity	Myo1b	IDA		Rat	PMID:20080738|RGD:8554448
Molecular Function	GO:0000146	microfilament motor activity	MYO1B	IMP		Human	PMID:21666684
Molecular Function	GO:0000146	microfilament motor activity	Myo1b	IDA		Rat	PMID:15647165|RGD:11532774
Molecular Function	GO:0000146	microfilament motor activity	Myo1b	IDA		Rat	PMID:16254000|RGD:8554605
Molecular Function	GO:0000146	microfilament motor activity	Myo1b	IDA		Rat	PMID:17298083|RGD:8554192
Molecular Function	GO:0000146	microfilament motor activity	Myo1b	IDA		Rat	PMID:21680745|RGD:7349312
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Myo1b	IDA		Rat	PMID:20610386|RGD:8554686
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Myo1b	IDA		Rat	PMID:20610386|RGD:8554686
Molecular Function	GO:0005515	protein binding	MYO1B	IPI	UniProtKB:P51687	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYO1B	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Cellular Component	GO:0005884	actin filament	MYO1B	IDA		Human	PMID:16219689
Cellular Component	GO:0045177	apical part of cell	Myo1b	IDA		Rat	PMID:12486594|RGD:1298992
Cellular Component	GO:0005903	brush border	Myo1b	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005903	brush border	Myo1b	IDA		Rat	PMID:11546671|RGD:628448
Cellular Component	GO:0071944	cell periphery	Myo1b	IDA		Rat	PMID:20610386|RGD:8554686
Cellular Component	GO:0005737	cytoplasm	Myo1b	IDA		Rat	PMID:11546671|RGD:628448
Cellular Component	GO:0005737	cytoplasm	Myo1b	IDA		Rat	PMID:17298083|RGD:8554192
Cellular Component	GO:0005769	early endosome	MYO1B	IDA		Human	PMID:16219689
Cellular Component	GO:0010008	endosome membrane	MYO1B	IDA		Human	PMID:16219689
Cellular Component	GO:0070062	extracellular exosome	MYO1B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MYO1B	HDA		Human	PMID:19199708
Cellular Component	GO:0030175	filopodium	Myo1b	IDA		Rat	PMID:20610386|RGD:8554686
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MYO1B	IDA		Human	PMID:21666684
Cellular Component	GO:0005886	plasma membrane	MYO1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Myo1b	IDA		Rat	PMID:17298083|RGD:8554192
Cellular Component	GO:0032588	trans-Golgi network membrane	MYO1B	IDA		Human	PMID:21666684
Biological Process	GO:0051017	actin filament bundle assembly	Myo1b	IDA		Rat	PMID:15475577|RGD:8554400
Biological Process	GO:0007015	actin filament organization	MYO1B	IMP		Human	PMID:21666684
Biological Process	GO:0030048	actin filament-based movement	Myo1b	IDA		Rat	PMID:17298083|RGD:8554192
Biological Process	GO:0030048	actin filament-based movement	Myo1b	IDA		Rat	PMID:20080738|RGD:8554448
Biological Process	GO:0006892	post-Golgi vesicle-mediated transport	MYO1B	IMP		Human	PMID:21666684
Biological Process	GO:0033572	transferrin transport	Myo1b	IDA		Mouse	PMID:12490950

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern