Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO3A
  • Mouse genes Myo3a
  • Rat genes Myo3a
  • Zfish genes myo3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Myo3a	IDA		Mouse	PMID:22264607
Molecular Function	GO:0043531	ADP binding	MYO3A	IDA		Human	PMID:12672820
Molecular Function	GO:0005516	calmodulin binding	MYO3A	IDA		Human	PMID:12672820
Molecular Function	GO:0000146	microfilament motor activity	MYO3A	IDA		Human	PMID:1262820
Molecular Function	GO:0000146	microfilament motor activity	MYO3A	IDA		Human	PMID:12672820
Molecular Function	GO:0000146	microfilament motor activity	MYO3A	IMP		Human	PMID:17021180
Molecular Function	GO:0000146	microfilament motor activity	Myo3a	IDA		Mouse	PMID:22264607
Molecular Function	GO:0060002	plus-end directed microfilament motor activity	MYO3A	IDA		Human	PMID:12672820
Molecular Function	GO:0005515	protein binding	MYO3A	IPI	UniProtKB:Q8NDC4	Human	PMID:25822849
Molecular Function	GO:0005515	protein binding	Myo3a	IPI	UniProtKB:Q3UYR4|UniProtKB:Q9ET47	Mouse	MGI:MGI:5805759|PMID:26926603
Molecular Function	GO:0005515	protein binding	Myo3a	IPI	UniProtKB:Q6PGF2	Mouse	MGI:MGI:5766107|PMID:26754646
Molecular Function	GO:0004672	protein kinase activity	MYO3A	IDA		Human	PMID:12672820
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Myo3a	IDA		Mouse	PMID:21895655
Cellular Component	GO:0005737	cytoplasm	MYO3A	IDA		Human	PMID:25822849
Cellular Component	GO:0031941	filamentous actin	MYO3A	IDA		Human	PMID:12672820
Cellular Component	GO:0030175	filopodium	MYO3A	IDA		Human	PMID:17021180
Cellular Component	GO:0032433	filopodium tip	MYO3A	IDA		Human	PMID:25822849
Cellular Component	GO:0032433	filopodium tip	Myo3a	IDA		Mouse	PMID:22264607
Cellular Component	GO:0001917	photoreceptor inner segment	Myo3a	IDA		Mouse	PMID:19332056
Cellular Component	GO:0032426	stereocilium tip	Myo3a	IDA		Mouse	MGI:MGI:5766107|PMID:26754646
Cellular Component	GO:0032426	stereocilium tip	Myo3a	EXP		Mouse	PMID:26754646
Cellular Component	GO:0032426	stereocilium tip	Myo3a	IDA		Mouse	PMID:21165622
Cellular Component	GO:0032426	stereocilium tip	Myo3a	IDA		Mouse	PMID:22264607
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo3a	IMP		Mouse	PMID:26754646
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo3a	IGI	MGI:2448580	Mouse	PMID:26754646
Biological Process	GO:0090103	cochlea morphogenesis	Myo3a	IMP		Mouse	MGI:MGI:5766107|PMID:26754646
Biological Process	GO:0048839	inner ear development	Myo3a	IMP	MGI:MGI:4849286	Mouse	PMID:21165622
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Myo3a	IDA		Mouse	PMID:21895655
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Myo3a	IDA		Mouse	PMID:21895655
Biological Process	GO:0051491	positive regulation of filopodium assembly	Myo3a	IGI	MGI:MGI:1861630	Mouse	PMID:22264607
Biological Process	GO:0046777	protein autophosphorylation	MYO3A	IDA		Human	PMID:12672820
Biological Process	GO:0046777	protein autophosphorylation	Myo3a	IDA		Mouse	PMID:21895655
Biological Process	GO:0030832	regulation of actin filament length	Myo3a	IGI	MGI:2448580	Mouse	PMID:26754646
Biological Process	GO:0030832	regulation of actin filament length	Myo3a	IMP		Mouse	PMID:26754646
Biological Process	GO:0007605	sensory perception of sound	MYO3A	IMP		Human	PMID:12032315
Biological Process	GO:0007605	sensory perception of sound	Myo3a	IMP		Mouse	PMID:26754646
Biological Process	GO:0007605	sensory perception of sound	Myo3a	IGI	MGI:2448580	Mouse	PMID:26754646
Biological Process	GO:0007605	sensory perception of sound	Myo3a	IMP	MGI:MGI:4849286	Mouse	PMID:21165622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern