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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myo5a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo5a
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003779actin bindingMyo5aIDAMousePMID:16137617
Molecular FunctionGO:0003779actin bindingMyo5aIDAMousePMID:12403814
Molecular FunctionGO:0003779actin bindingMyo5aIDAMousePMID:11706052
Molecular FunctionGO:0005524ATP bindingMyo5aIDARatPMID:16030255|RGD:1581734
Molecular FunctionGO:0043008ATP-dependent protein bindingMyo5aIPIRGD:69430RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0005509calcium ion bindingMyo5aIDAMousePMID:15007063
Molecular FunctionGO:0048306calcium-dependent protein bindingMyo5aIPIRGD:69430RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0005516calmodulin bindingMyo5aIDAMousePMID:25260918
Molecular FunctionGO:0005516calmodulin bindingMyo5aIDAMousePMID:11706052
Molecular FunctionGO:0005516calmodulin bindingMyo5aIDAMousePMID:15007063
Molecular FunctionGO:0003774cytoskeletal motor activityMyo5aIDAMousePMID:11706052
Molecular FunctionGO:0003774cytoskeletal motor activityMyo5aIMPRatPMID:16190983|RGD:1600832
Molecular FunctionGO:0097718disordered domain specific bindingMyo5aIPIUniProtKB:Q91V27MouseMGI:MGI:5882888|PMID:17513864
Molecular FunctionGO:0042802identical protein bindingMyo5aIPIUniProtKB:Q99104MouseMGI:MGI:6093185|PMID:20018767
Molecular FunctionGO:0042802identical protein bindingMyo5aIPIUniProtKB:Q99104MouseMGI:MGI:5917836|PMID:20133809
Molecular FunctionGO:0000146microfilament motor activityMyo5aIDAMousePMID:15007063
Molecular FunctionGO:0000146microfilament motor activityMyo5aIDAMousePMID:11706052
Molecular FunctionGO:0000146microfilament motor activityMyo5aIDARatPMID:16030255|RGD:1581734
Molecular FunctionGO:0005515protein bindingMYO5AIPIUniProtKB:Q9BV36HumanPMID:11980908
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:Q9ERI2MousePMID:11266470
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:P15331MousePMID:12403814
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:Q91V27MousePMID:14730011
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:Q9ERI2MousePMID:14730011
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:P08551MousePMID:12403814
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:P03995MousePMID:12403814
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:Q9ESN6MousePMID:11432975
Molecular FunctionGO:0005515protein bindingMyo5aIPIPR:Q3V0J1MousePMID:20375344
Molecular FunctionGO:0005515protein bindingMyo5aIPIRGD:1308864RatPMID:19103256|RGD:9685716
Molecular FunctionGO:0019901protein kinase bindingMyo5aIPIRGD:708455RatPMID:25456499|RGD:11532775
Molecular FunctionGO:0044877protein-containing complex bindingMyo5aIDARatPMID:16030255|RGD:1581734
Molecular FunctionGO:0003723RNA bindingMYO5AHDAHumanPMID:22681889
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:O00194HumanPMID:15357836
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:O95716HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P20336HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P20337HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P20340HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P57735HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P61006HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P61106HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:P62491HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:Q15907HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:Q96DA2HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:Q96E17HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMYO5AIPIUniProtKB:Q9NRW1HumanPMID:24006491
Molecular FunctionGO:0031267small GTPase bindingMyo5aIPIUniProtKB:P61026MouseMGI:MGI:5463529|PMID:22908308
Molecular FunctionGO:0000149SNARE bindingMyo5aIPIRGD:3728RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0000149SNARE bindingMyo5aIPIRGD:3949RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0017075syntaxin-1 bindingMyo5aIPIRGD:69430RatPMID:16030255|RGD:1581734
Cellular ComponentGO:0005884actin filamentMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0042641actomyosinMyo5aIDAMousePMID:8188282
Cellular ComponentGO:0042642actomyosin, myosin complex partMyo5aIDARatPMID:16030255|RGD:1581734
Cellular ComponentGO:0030424axonMyo5aIDARatPMID:11977091|RGD:1298990
Cellular ComponentGO:0005737cytoplasmMYO5AIDAHumanPMID:9852149
Cellular ComponentGO:0005737cytoplasmMyo5aIDAMousePMID:9133672
Cellular ComponentGO:0005737cytoplasmMyo5aIDAMousePMID:8962090
Cellular ComponentGO:0005737cytoplasmMyo5aIDARatPMID:16190983|RGD:1600832
Cellular ComponentGO:0005829cytosolMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0030425dendriteMyo5aIDARatPMID:25456499|RGD:11532775
Cellular ComponentGO:0005769early endosomeMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0005783endoplasmic reticulumMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0070062extracellular exosomeMYO5AHDAHumanPMID:23533145
Cellular ComponentGO:0032433filopodium tipMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0098978glutamatergic synapseMyo5aIMPMousePMID:21151132
Cellular ComponentGO:0098978glutamatergic synapseMyo5aIDAMousePMID:21151132
Cellular ComponentGO:0098978glutamatergic synapseMyo5aIDARatPMID:18311135|RGD:13702420
Cellular ComponentGO:0098978glutamatergic synapseMyo5aIMPRatPMID:18311135|RGD:13702420
Cellular ComponentGO:0005794Golgi apparatusMyo5aIDAMousePMID:14724135
Cellular ComponentGO:0032593insulin-responsive compartmentMyo5aIDAMouseMGI:MGI:5463529|PMID:22908308
Cellular ComponentGO:0005882intermediate filamentMyo5aIDAMousePMID:8188282
Cellular ComponentGO:0005770late endosomeMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0005764lysosomeMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0042470melanosomeMYO5AIDAHumanPMID:11980908
Cellular ComponentGO:0042470melanosomeMyo5aIDAMousePMID:9133672
Cellular ComponentGO:0042470melanosomeMyo5aIDAMousePMID:11886590
Cellular ComponentGO:0042470melanosomeMyo5aIDAMousePMID:11887186
Cellular ComponentGO:0016020membraneMYO5AHDAHumanPMID:19946888
Cellular ComponentGO:0016020membraneMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0016459myosin complexMyo5aIDAMousePMID:12403814
Cellular ComponentGO:0016459myosin complexMyo5aIDAMousePMID:11706052
Cellular ComponentGO:0043005neuron projectionMyo5aIDARatPMID:16166155|RGD:1581733
Cellular ComponentGO:0043025neuronal cell bodyMyo5aIDAMousePMID:1996138
Cellular ComponentGO:0043025neuronal cell bodyMyo5aIDARatPMID:11977091|RGD:1298990
Cellular ComponentGO:0043025neuronal cell bodyMyo5aIDARatPMID:14568019|RGD:2306438
Cellular ComponentGO:0043025neuronal cell bodyMyo5aIDARatPMID:16166155|RGD:1581733
Cellular ComponentGO:0005777peroxisomeMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0001750photoreceptor outer segmentMyo5aIDAMousePMID:14978221
Cellular ComponentGO:0098794postsynapseMyo5aIDAMousePMID:21151132
Cellular ComponentGO:0098794postsynapseMyo5aIMPMousePMID:21151132
Cellular ComponentGO:0098794postsynapseMyo5aIDARatPMID:18311135|RGD:13702420
Cellular ComponentGO:0098794postsynapseMyo5aIMPRatPMID:18311135|RGD:13702420
Cellular ComponentGO:0098871postsynaptic actin cytoskeletonMyo5aIDARatPMID:18311135|RGD:13702420
Cellular ComponentGO:0098871postsynaptic actin cytoskeletonMyo5aIMPRatPMID:18311135|RGD:13702420
Cellular ComponentGO:0055037recycling endosomeMYO5AIDAHumanPMID:24006491
Cellular ComponentGO:0055037recycling endosomeMyo5aIDARatPMID:25456499|RGD:11532775
Cellular ComponentGO:1990904ribonucleoprotein complexMyo5aIDARatPMID:24272908|RGD:11532778
Cellular ComponentGO:0001726ruffleMYO5AIDAHumanPMID:9852149
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseMyo5aIDARatPMID:18311135|RGD:13702420
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseMyo5aIMPRatPMID:18311135|RGD:13702420
Cellular ComponentGO:0030141secretory granuleMyo5aIDAMousePMID:15788565
Cellular ComponentGO:0030141secretory granuleMyo5aIDARatPMID:12615975|RGD:1298991
Cellular ComponentGO:0005790smooth endoplasmic reticulumMyo5aIDAMousePMID:21151132
Cellular ComponentGO:0005790smooth endoplasmic reticulumMyo5aIMPMousePMID:21151132
Cellular ComponentGO:0008021synaptic vesicleMyo5aIDARatPMID:16030255|RGD:1581734
Cellular ComponentGO:0016461unconventional myosin complexMyo5aIMPMouseMGI:MGI:5882888|PMID:17513864
Cellular ComponentGO:0031982vesicleMYO5AIDAHumanPMID:24006491
Biological ProcessGO:0030048actin filament-based movementMyo5aIDAMousePMID:15007063
Biological ProcessGO:0030048actin filament-based movementMyo5aIDARatPMID:16030255|RGD:1581734
Biological ProcessGO:0042640anagenMyo5aIMPMGI:MGI:1856004MousePMID:15550542
Biological ProcessGO:0099640axo-dendritic protein transportMyo5aIMPRatPMID:24637809|RGD:11532780
Biological ProcessGO:0032869cellular response to insulin stimulusMyo5aIMPMouseMGI:MGI:5463529|PMID:22908308
Biological ProcessGO:0007268chemical synaptic transmissionMyo5aIMPMGI:MGI:1856005MousePMID:15316067
Biological ProcessGO:0048066developmental pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:15550542
Biological ProcessGO:0042417dopamine metabolic processMyo5aIMPRatPMID:29217155|RGD:42721980
Biological ProcessGO:0051643endoplasmic reticulum localizationMyo5aIMPMGI:MGI:1856005MousePMID:8899740
Biological ProcessGO:0051643endoplasmic reticulum localizationMyo5aIMPMGI:MGI:1858520MousePMID:10749990
Biological ProcessGO:0099089establishment of endoplasmic reticulum localization to postsynapseMyo5aIDAMousePMID:21151132
Biological ProcessGO:0099089establishment of endoplasmic reticulum localization to postsynapseMyo5aIMPMousePMID:21151132
Biological ProcessGO:0006887exocytosisMyo5aIMPMousePMID:15788565
Biological ProcessGO:0048820hair follicle maturationMyo5aIMPMGI:MGI:5641704MousePMID:25340873
Biological ProcessGO:0030073insulin secretionMyo5aIMPMousePMID:15788565
Biological ProcessGO:0031987locomotion involved in locomotory behaviorMyo5aIMPMGI:MGI:1856005MousePMID:10536275
Biological ProcessGO:0031987locomotion involved in locomotory behaviorMyo5aIMPMGI:MGI:1858520MousePMID:10749990
Biological ProcessGO:0042759long-chain fatty acid biosynthetic processMyo5aIMPMGI:MGI:1856005MousePMID:1150661
Biological ProcessGO:0016236macroautophagyMyo5aIMPRatPMID:29217155|RGD:42721980
Biological ProcessGO:0042438melanin biosynthetic processMyo5aIMPMGI:MGI:1856004MousePMID:7665913
Biological ProcessGO:0006582melanin metabolic processMyo5aIMPMGI:MGI:1856004MousePMID:9548375
Biological ProcessGO:0030318melanocyte differentiationMyo5aIMPMGI:MGI:1856004MousePMID:1996138
Biological ProcessGO:0030318melanocyte differentiationMyo5aIMPMGI:MGI:1856004MousePMID:2379821
Biological ProcessGO:0030318melanocyte differentiationMyo5aIMPMGI:MGI:1856004MousePMID:7828830
Biological ProcessGO:0032400melanosome localizationMyo5aIMPMGI:MGI:1856004MousePMID:8962090
Biological ProcessGO:0032400melanosome localizationMyo5aIMPMousePMID:14730011
Biological ProcessGO:0032400melanosome localizationMyo5aIMPMGI:MGI:1856004MousePMID:11266470
Biological ProcessGO:0032402melanosome transportMyo5aIMPMGI:MGI:1858077MousePMID:11266473
Biological ProcessGO:0032402melanosome transportMyo5aIDAMousePMID:9133672
Biological ProcessGO:0032402melanosome transportMyo5aIMPMGI:MGI:1856004MousePMID:9548375
Biological ProcessGO:0032402melanosome transportMyo5aIMPMousePMID:24721909
Biological ProcessGO:0042552myelinationMyo5aIMPMGI:MGI:1856005MousePMID:1150661
Biological ProcessGO:0033602negative regulation of dopamine secretionMyo5aIMPRatPMID:22639889|RGD:42722007
Biological ProcessGO:0051967negative regulation of synaptic transmission, glutamatergicMyo5aIMPRatPMID:27771352|RGD:41412185
Biological ProcessGO:0050885neuromuscular process controlling balanceMyo5aIMPMGI:MGI:1856005MouseMGI:MGI:61192
Biological ProcessGO:0042476odontogenesisMyo5aIDAMousePMID:14730011
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858062MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:13880466
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1891639MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMousePMID:9560408
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:5641704MousePMID:25340873
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856847MousePMID:3141922
Biological ProcessGO:0043473pigmentationMyo5aIMPMousePMID:24721909
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:3583341MousePMID:6305507
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858064MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:2379821
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858059MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856008MousePMID:9560409
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858066MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1891626MousePMID:6305507
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:6305507
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858065MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858058MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858063MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:2658702MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:17247639
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1860204MousePMID:9560409
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856407MousePMID:9560409
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:6098826
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:7828830
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856004MousePMID:7774591
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858061MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1856005MouseMGI:MGI:61192
Biological ProcessGO:0043473pigmentationMyo5aIMPMGI:MGI:1858060MousePMID:3422417
Biological ProcessGO:0043473pigmentationMyo5aIMPRatPMID:10920234|RGD:61493
Biological ProcessGO:1900078positive regulation of cellular response to insulin stimulusMyo5aIMPRatPMID:24478457|RGD:11532776
Biological ProcessGO:1904960positive regulation of cytochrome-c oxidase activityMyo5aIMPRatPMID:29217155|RGD:42721980
Biological ProcessGO:1903078positive regulation of protein localization to plasma membraneMyo5aIMPRatPMID:24508725|RGD:11532777
Biological ProcessGO:1904754positive regulation of vascular associated smooth muscle cell migrationMyo5aIMPRatPMID:24790701|RGD:11532779
Biological ProcessGO:0006892post-Golgi vesicle-mediated transportMYO5AIMPHumanPMID:24006491
Biological ProcessGO:0072659protein localization to plasma membraneMyo5aIMPMouseMGI:MGI:5463529|PMID:22908308
Biological ProcessGO:0065003protein-containing complex assemblyMyo5aIMPRatPMID:11470781|RGD:2306437
Biological ProcessGO:0150103reactive gliosisMyo5aIMPRatPMID:22639889|RGD:42722007
Biological ProcessGO:0017157regulation of exocytosisMyo5aIMPRatPMID:16030255|RGD:1581734
Biological ProcessGO:0017157regulation of exocytosisMyo5aIMPRatPMID:16190983|RGD:1600832
Biological ProcessGO:0031585regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityMyo5aIMPMGI:MGI:1856004MousePMID:11086997
Biological ProcessGO:0099566regulation of postsynaptic cytosolic calcium ion concentrationMyo5aIDAMousePMID:21151132
Biological ProcessGO:0099566regulation of postsynaptic cytosolic calcium ion concentrationMyo5aIMPMousePMID:21151132
Biological ProcessGO:0032252secretory granule localizationMyo5aIMPMousePMID:15788565
Biological ProcessGO:0032252secretory granule localizationMyo5aIDARatPMID:12615975|RGD:1298991
Biological ProcessGO:0032252secretory granule localizationMyo5aIMPRatPMID:16190983|RGD:1600832
Biological ProcessGO:0050808synapse organizationMyo5aIMPMGI:MGI:1856005MousePMID:15316067
Biological ProcessGO:0030050vesicle transport along actin filamentMYO5AIMPHumanPMID:24006491
Biological ProcessGO:0030050vesicle transport along actin filamentMyo5aIMPRatPMID:11470781|RGD:2306437
Biological ProcessGO:0030050vesicle transport along actin filamentMyo5aIMPRatPMID:16190983|RGD:1600832
Biological ProcessGO:0016192vesicle-mediated transportMyo5aIMPMouseMGI:MGI:5463529|PMID:22908308
Biological ProcessGO:0007601visual perceptionMyo5aIMPMGI:MGI:1856005MousePMID:15316067

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory