Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myo6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYO6
- Mouse genes Myo6
- Rat genes Myo6
- Zfish genes myo6a,myo6b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	MYO6	IDA		Human	PMID:9852149
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:P05549	Human	PMID:11447109
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:P98078	Human	PMID:11967127
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:P98082	Human	PMID:11967127
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:P98082	Human	PMID:15837803
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:Q96CV9	Human	PMID:15837803
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:Q9Z0G0	Human	PMID:16908842
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:P98078	Human	PMID:22323290
Molecular Function	GO:0005515	protein binding	MYO6	IPI	UniProtKB:Q96II8	Human	PMID:29467281
Molecular Function	GO:0005515	protein binding	Myo6	IPI	PR:Q66T02	Mouse	PMID:16467373
Molecular Function	GO:0005515	protein binding	Myo6	IPI	PR:P17809	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Myo6	IPI	PR:Q3V0J1	Mouse	PMID:20375344
Molecular Function	GO:0005515	protein binding	Myo6	IPI	PR:Q9Z0G0	Mouse	PMID:16819522
Molecular Function	GO:0005515	protein binding	Myo6	IPI	PR:Q9Z0G0	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Myo6	IPI	RGD:1359203	Rat	PMID:15505042\|RGD:1359754
Molecular Function	GO:0005515	protein binding	Myo6	IPI	UniProtKB:Q6IMY8	Rat	PMID:29293066\|RGD:150521645
Cellular Component	GO:0045177	apical part of cell	Myo6	IDA		Rat	PMID:11934687\|RGD:2314967
Cellular Component	GO:0030424	axon	Myo6	IDA		Mouse	PMID:16819522
Cellular Component	GO:0005903	brush border	Myo6	IDA		Mouse	MGI:MGI:5621262\|PMID:22114352
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	MYO6	IDA		Human	PMID:11447109
Cellular Component	GO:0098683	cochlear hair cell ribbon synapse	Myo6	IDA		Mouse	PMID:19744958
Cellular Component	GO:0005737	cytoplasm	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0005737	cytoplasm	MYO6	IDA		Human	PMID:16949370
Cellular Component	GO:0005737	cytoplasm	MYO6	IDA		Human	PMID:9852149
Cellular Component	GO:0005737	cytoplasm	Myo6	IDA		Mouse	PMID:21300049
Cellular Component	GO:0005737	cytoplasm	Myo6	IDA		Mouse	PMID:20016102
Cellular Component	GO:0005737	cytoplasm	Myo6	IDA		Rat	PMID:16107581\|RGD:2314963
Cellular Component	GO:0031410	cytoplasmic vesicle	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0031410	cytoplasmic vesicle	Myo6	IDA		Rat	PMID:15837803\|RGD:8554668
Cellular Component	GO:0030139	endocytic vesicle	Myo6	IDA		Rat	PMID:15355515\|RGD:2314965
Cellular Component	GO:0070062	extracellular exosome	MYO6	HDA		Human	PMID:19056867
Cellular Component	GO:0031941	filamentous actin	MYO6	IDA		Human	PMID:9852149
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IDA		Mouse	PMID:16819522
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IMP		Mouse	PMID:16819522
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IPI		Mouse	PMID:15657400
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IDA		Mouse	PMID:15657400
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IMP		Mouse	PMID:15657400
Cellular Component	GO:0098978	glutamatergic synapse	Myo6	IEP		Mouse	PMID:15657400
Cellular Component	GO:0005794	Golgi apparatus	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0005794	Golgi apparatus	Myo6	IDA		Rat	PMID:15837803\|RGD:8554668
Cellular Component	GO:0005794	Golgi apparatus	Myo6	IDA		Rat	PMID:9852149\|RGD:2314969
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Myo6	IDA		Rat	PMID:9852149\|RGD:2314969
Cellular Component	GO:0016020	membrane	MYO6	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Myo6	IDA		Rat	PMID:16107581\|RGD:2314963
Cellular Component	GO:0005902	microvillus	Myo6	IDA		Rat	PMID:18653479\|RGD:2314961
Cellular Component	GO:0043025	neuronal cell body	Myo6	IDA		Mouse	PMID:16819522
Cellular Component	GO:0031965	nuclear membrane	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0005654	nucleoplasm	MYO6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MYO6	IDA		Human	PMID:16949370
Cellular Component	GO:0005634	nucleus	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MYO6	IDA		Human	PMID:9852149
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo6	IDA		Mouse	PMID:22105175
Cellular Component	GO:0005886	plasma membrane	Myo6	IPI	PR:Q9Z0G0	Mouse	PMID:15975910
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myo6	IPI		Mouse	PMID:15657400
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myo6	IEP		Mouse	PMID:15657400
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myo6	IDA		Mouse	PMID:15657400
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Myo6	IMP		Mouse	PMID:15657400
Cellular Component	GO:0014069	postsynaptic density	Myo6	IDA		Mouse	PMID:15657400
Cellular Component	GO:0014069	postsynaptic density	Myo6	IMP		Mouse	PMID:15657400
Cellular Component	GO:0014069	postsynaptic density	Myo6	IPI		Mouse	PMID:15657400
Cellular Component	GO:0098833	presynaptic endocytic zone	Myo6	IDA		Mouse	PMID:19744958
Cellular Component	GO:0032991	protein-containing complex	Myo6	IDA		Rat	PMID:12050163\|RGD:625490
Cellular Component	GO:0001726	ruffle	MYO6	IDA		Human	PMID:16507995
Cellular Component	GO:0001726	ruffle	MYO6	IDA		Human	PMID:9852149
Cellular Component	GO:0032587	ruffle membrane	Myo6	IDA		Rat	PMID:9852149\|RGD:2314969
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo6	IDA		Mouse	PMID:16819522
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Myo6	IMP		Mouse	PMID:16819522
Cellular Component	GO:0012506	vesicle membrane	Myo6	IPI	PR:Q9Z0G0	Mouse	PMID:15975910
Biological Process	GO:0035479	angioblast cell migration from lateral mesoderm to midline	myo6a	IMP	ZFIN:ZDB-MRPHLNO-101111-1	Zfish	PMID:20434959
Biological Process	GO:0048844	artery morphogenesis	myo6a	IMP	ZFIN:ZDB-MRPHLNO-101111-1	Zfish	PMID:20434959
Biological Process	GO:0060117	auditory receptor cell development	myo6a	IMP	ZFIN:ZDB-MRPHLNO-221114-1	Zfish	PMID:35328790
Biological Process	GO:0071257	cellular response to electrical stimulus	Myo6	IMP		Mouse	PMID:21052544
Biological Process	GO:0007268	chemical synaptic transmission	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:16819522
Biological Process	GO:0016358	dendrite development	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:15657400
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo6b	IMP	ZFIN:ZDB-GENO-040820-1	Zfish	PMID:15282151
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo6b	IMP	ZFIN:ZDB-GENO-040820-2	Zfish	PMID:15282151
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo6b	IMP	ZFIN:ZDB-GENO-040820-4	Zfish	PMID:15282151
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo6b	IMP	ZFIN:ZDB-GENO-040820-3	Zfish	PMID:15282151
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo6b	IMP	ZFIN:ZDB-GENO-040915-1	Zfish	PMID:15317943
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	MYO6	IDA		Human	PMID:16507995
Biological Process	GO:0006897	endocytosis	MYO6	IMP		Human	PMID:15247260
Biological Process	GO:0006897	endocytosis	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:15657400
Biological Process	GO:0021782	glial cell development	myo6b	IMP	ZFIN:ZDB-CRISPR-191008-11,ZFIN:ZDB-CRISPR-191008-12	Zfish	PMID:30924555
Biological Process	GO:0014047	glutamate secretion	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:16819522
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:5980120
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:10525338
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:7493015
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	myo6b	IMP	ZFIN:ZDB-GENO-040820-2	Zfish	PMID:15282151
Biological Process	GO:0048839	inner ear development	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:5980120
Biological Process	GO:0048839	inner ear development	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:10525338
Biological Process	GO:0048839	inner ear development	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:7493015
Biological Process	GO:0042472	inner ear morphogenesis	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:7493015
Biological Process	GO:0007626	locomotory behavior	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:16962269
Biological Process	GO:0071599	otic vesicle development	myo6a	IMP	ZFIN:ZDB-MRPHLNO-221114-1	Zfish	PMID:35328790
Biological Process	GO:0048840	otolith development	myo6a	IMP	ZFIN:ZDB-MRPHLNO-221114-1	Zfish	PMID:35328790
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Myo6	IDA		Mouse	PMID:15657400
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Myo6	IPI		Mouse	PMID:15657400
Biological Process	GO:0098884	postsynaptic neurotransmitter receptor internalization	Myo6	IMP		Mouse	PMID:15657400
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Myo6	IDA		Mouse	PMID:16819522
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Myo6	IMP		Mouse	PMID:16819522
Biological Process	GO:0006605	protein targeting	Myo6	IPI	PR:Q9Z0G0	Mouse	PMID:15975910
Biological Process	GO:0051046	regulation of secretion	MYO6	IMP		Human	PMID:15837803
Biological Process	GO:0048167	regulation of synaptic plasticity	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:16819522
Biological Process	GO:0010996	response to auditory stimulus	myo6a	IMP	ZFIN:ZDB-MRPHLNO-221114-1	Zfish	PMID:35328790
Biological Process	GO:0009410	response to xenobiotic stimulus	Myo6	IDA		Rat	PMID:17652375\|RGD:2314962
Biological Process	GO:0060041	retina development in camera-type eye	myo6b	IMP	ZFIN:ZDB-CRISPR-191008-11,ZFIN:ZDB-CRISPR-191008-12	Zfish	PMID:30924555
Biological Process	GO:0007605	sensory perception of sound	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:10525338
Biological Process	GO:0007605	sensory perception of sound	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:5980120
Biological Process	GO:0007605	sensory perception of sound	Myo6	IMP	MGI:MGI:3708361	Mouse	PMID:17329413
Biological Process	GO:0007605	sensory perception of sound	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:7493015
Biological Process	GO:0007605	sensory perception of sound	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:15657400
Biological Process	GO:0007416	synapse assembly	Myo6	IMP	MGI:MGI:1856555	Mouse	PMID:15657400

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.