Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Myo7a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MYO7A
- Mouse genes Myo7a
- Rat genes Myo7a
- Zfish genes myo7aa,myo7ab
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0051015	actin filament binding	MYO7A	IDA		Human	PMID:21687988
Molecular Function	GO:0043531	ADP binding	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0005524	ATP binding	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0005516	calmodulin binding	MYO7A	IMP		Human	PMID:15300860
Molecular Function	GO:0005516	calmodulin binding	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0003774	cytoskeletal motor activity	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0042802	identical protein binding	Myo7a	IPI	RGD:628830	Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0000146	microfilament motor activity	MYO7A	IDA		Human	PMID:21687988
Molecular Function	GO:0000146	microfilament motor activity	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0005515	protein binding	MYO7A	IPI	UniProtKB:Q8NFW9	Human	PMID:11964381
Molecular Function	GO:0005515	protein binding	MYO7A	IPI	UniProtKB:O75838	Human	PMID:23023331
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	UniProtKB:O70309\|UniProtKB:P18084	Mouse	MGI:MGI:5585527\|PMID:24997346
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	UniProtKB:E9Q9W7	Mouse	MGI:MGI:5806014\|PMID:27525485
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	UniProtKB:Q91ZQ5	Mouse	MGI:MGI:5050344\|PMID:21493626
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	UniProtKB:Q80VW5	Mouse	MGI:MGI:3528099\|PMID:15590698
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q9ES64	Mouse	PMID:15590703
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q8VHN7	Mouse	PMID:17567809
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q7TPH6	Mouse	PMID:15976448
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q99PJ1	Mouse	PMID:16481439
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q2QI47	Mouse	PMID:17567809
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q9ES64	Mouse	PMID:12485990
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:A2ALU4	Mouse	PMID:17666436
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	PR:Q80T11	Mouse	PMID:15590703
Molecular Function	GO:0005515	protein binding	Myo7a	IPI	RGD:70948	Rat	PMID:23329832\|RGD:8662293
Molecular Function	GO:0019904	protein domain specific binding	Myo7a	IPI	PR:A2ALU4	Mouse	PMID:17666436
Molecular Function	GO:0044877	protein-containing complex binding	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Molecular Function	GO:0030507	spectrin binding	MYO7A	IDA		Human	PMID:23704327
Cellular Component	GO:0016324	apical plasma membrane	Myo7a	IDA		Mouse	PMID:9620764
Cellular Component	GO:0005737	cytoplasm	MYO7A	IDA		Human	PMID:23704327
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:21146598
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:15905332
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:20016102
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:18796539
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:14978221
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:15590703
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:11023859
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:25535395
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:15572405
Cellular Component	GO:0005737	cytoplasm	Myo7a	IDA		Mouse	PMID:17666436
Cellular Component	GO:0005829	cytosol	MYO7A	IDA		Human	PMID:15300860
Cellular Component	GO:0005765	lysosomal membrane	MYO7A	IDA		Human	PMID:16001398
Cellular Component	GO:0042470	melanosome	Myo7a	IDA		Mouse	PMID:14978221
Cellular Component	GO:0042470	melanosome	Myo7a	IDA		Mouse	PMID:15572405
Cellular Component	GO:0016459	myosin complex	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Cellular Component	GO:0031477	myosin VII complex	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Cellular Component	GO:0032391	photoreceptor connecting cilium	Myo7a	IDA		Mouse	PMID:10414956
Cellular Component	GO:0001917	photoreceptor inner segment	MYO7A	IDA		Human	PMID:8842737
Cellular Component	GO:0001750	photoreceptor outer segment	MYO7A	IDA		Human	PMID:8842737
Cellular Component	GO:0032420	stereocilium	Myo7a	IDA		Mouse	MGI:MGI:5806014\|PMID:27525485
Cellular Component	GO:0032420	stereocilium	Myo7a	EXP		Mouse	PMID:26754646
Cellular Component	GO:0032420	stereocilium	Myo7a	IDA		Mouse	PMID:20016102
Cellular Component	GO:0032420	stereocilium	Myo7a	IDA		Mouse	PMID:16481439
Cellular Component	GO:0032420	stereocilium	Myo7a	IDA		Mouse	PMID:12485990
Cellular Component	GO:0120044	stereocilium base	Myo7a	IDA		Mouse	MGI:MGI:3714249\|PMID:17567809
Cellular Component	GO:0045202	synapse	MYO7A	IDA		Human	PMID:8842737
Cellular Component	GO:0045202	synapse	Myo7a	IDA		Mouse	MGI:MGI:2180422\|PMID:11964381
Cellular Component	GO:1990435	upper tip-link density	Myo7a	IDA		Rat	PMID:21709241\|RGD:8699498
Biological Process	GO:0030048	actin filament-based movement	MYO7A	IDA		Human	PMID:21687988
Biological Process	GO:0030048	actin filament-based movement	Myo7a	IDA		Rat	PMID:12466270\|RGD:633398
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo7a	IMP		Mouse	PMID:17050716
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:12121736
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:11753415
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:11753415
Biological Process	GO:0030030	cell projection organization	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9435277
Biological Process	GO:0030030	cell projection organization	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9435277
Biological Process	GO:0030030	cell projection organization	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9435277
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	myo7aa	IMP		Zfish	PMID:9491988
Biological Process	GO:0006897	endocytosis	myo7aa	IMP		Zfish	PMID:10526320
Biological Process	GO:0050957	equilibrioception	MYO7A	IMP		Human	PMID:7870171
Biological Process	GO:0035315	hair cell differentiation	myo7aa	IMP		Zfish	PMID:10526320
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:12121736
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo7a	IMP	MGI:MGI:3511858	Mouse	PMID:15389316
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:11753415
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:11753415
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9435277
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:14198707
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:6627025
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9435277
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9435277
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1856716	Mouse	MGI:MGI:63006
Biological Process	GO:0048839	inner ear development	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:13336002
Biological Process	GO:0042472	inner ear morphogenesis	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:11753415
Biological Process	GO:0042472	inner ear morphogenesis	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:11753415
Biological Process	GO:0042472	inner ear morphogenesis	Myo7a	IMP	MGI:MGI:3511858	Mouse	PMID:15389316
Biological Process	GO:0042472	inner ear morphogenesis	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:5795329
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9435277
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155420	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155421	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9435277
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155417	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9435277
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9680294
Biological Process	GO:0060113	inner ear receptor cell differentiation	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9680294
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:18339676
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP	ZFIN:ZDB-GENO-020715-1	Zfish	PMID:10958658
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP	ZFIN:ZDB-GENO-980410-53	Zfish	PMID:10958658
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP	ZFIN:ZDB-GENO-980410-93	Zfish	PMID:10958658
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP		Zfish	PMID:24626987
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP	ZFIN:ZDB-GENO-980410-52	Zfish	PMID:10958658
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP		Zfish	PMID:9491988
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	myo7aa	IMP	ZFIN:ZDB-GENO-020715-2	Zfish	PMID:10958658
Biological Process	GO:0006886	intracellular protein transport	Myo7a	IMP	MGI:MGI:2155421	Mouse	PMID:10414956
Biological Process	GO:0007040	lysosome organization	MYO7A	IDA		Human	PMID:16001398
Biological Process	GO:0042490	mechanoreceptor differentiation	Myo7a	IMP	MGI:MGI:3527179	Mouse	PMID:17567809
Biological Process	GO:0006909	phagocytosis	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:12743369
Biological Process	GO:0001845	phagolysosome assembly	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:12743369
Biological Process	GO:0051875	pigment granule localization	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:14609561
Biological Process	GO:0051875	pigment granule localization	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:14978221
Biological Process	GO:0051875	pigment granule localization	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:15572405
Biological Process	GO:0051904	pigment granule transport	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9620764
Biological Process	GO:0051904	pigment granule transport	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:15572405
Biological Process	GO:0048563	post-embryonic animal organ morphogenesis	Myo7a	IMP	MGI:MGI:1856716	Mouse	MGI:MGI:63006
Biological Process	GO:0048563	post-embryonic animal organ morphogenesis	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:13336002
Biological Process	GO:0048563	post-embryonic animal organ morphogenesis	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:6627025
Biological Process	GO:0048563	post-embryonic animal organ morphogenesis	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:14198707
Biological Process	GO:0008104	protein localization	Myo7a	IDA		Mouse	MGI:MGI:5806014\|PMID:27525485
Biological Process	GO:0061512	protein localization to cilium	myo7aa	IMP	ZFIN:ZDB-GENO-171005-8	Zfish	PMID:28219986
Biological Process	GO:0007423	sensory organ development	myo7aa	IMP	ZFIN:ZDB-GENO-980410-52	Zfish	PMID:15634702
Biological Process	GO:0007600	sensory perception	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:11162241
Biological Process	GO:0050953	sensory perception of light stimulus	MYO7A	IMP		Human	PMID:11398101
Biological Process	GO:0050953	sensory perception of light stimulus	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:14609561
Biological Process	GO:0007605	sensory perception of sound	MYO7A	IMP		Human	PMID:7870171
Biological Process	GO:0007605	sensory perception of sound	MYO7A	IMP		Human	PMID:11398101
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:7870172
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1860092	Mouse	MGI:MGI:65387
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:6627025
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:7870172
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856555	Mouse	PMID:15657400
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:13336002
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155417	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1860092	Mouse	PMID:9435277
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:9435277
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155421	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:9435277
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155420	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:1856716	Mouse	PMID:14198707
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:3708382	Mouse	PMID:17329413
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:9680294
Biological Process	GO:0007605	sensory perception of sound	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:12121736
Biological Process	GO:0007601	visual perception	MYO7A	IMP		Human	PMID:7870171
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:2155417	Mouse	PMID:11222540
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:15316067
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:2155422	Mouse	PMID:11222540
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:2155423	Mouse	PMID:11222540
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:3045593	Mouse	PMID:11222540
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:2182918	Mouse	PMID:11222540
Biological Process	GO:0007601	visual perception	Myo7a	IMP	MGI:MGI:1857528	Mouse	PMID:11222540

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.