Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO9B
  • Mouse genes Myo9b
  • Rat genes Myo9b
  • Zfish genes myo9b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo9b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	MYO9B	IDA		Human	PMID:16338935
Molecular Function	GO:0003779	actin binding	MYO9B	IDA		Human	PMID:16616011
Molecular Function	GO:0003779	actin binding	MYO9B	IDA		Human	PMID:9490638
Molecular Function	GO:0003779	actin binding	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Molecular Function	GO:0051015	actin filament binding	Myo9b	IDA		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0051015	actin filament binding	Myo9b	IMP		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0051015	actin filament binding	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Molecular Function	GO:0043531	ADP binding	MYO9B	IDA		Human	PMID:16338935
Molecular Function	GO:0043531	ADP binding	Myo9b	IDA		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0043531	ADP binding	Myo9b	IMP		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0005524	ATP binding	MYO9B	IDA		Human	PMID:16338935
Molecular Function	GO:0005524	ATP binding	Myo9b	IDA		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0005524	ATP binding	Myo9b	IMP		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0016887	ATP hydrolysis activity	Myo9b	IDA		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0016887	ATP hydrolysis activity	Myo9b	IMP		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0043008	ATP-dependent protein binding	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Molecular Function	GO:0005516	calmodulin binding	MYO9B	IDA		Human	PMID:16338935
Molecular Function	GO:0005516	calmodulin binding	MYO9B	IDA		Human	PMID:9490638
Molecular Function	GO:0005096	GTPase activator activity	MYO9B	IDA		Human	PMID:15644318
Molecular Function	GO:0005096	GTPase activator activity	MYO9B	IDA		Human	PMID:26529257
Molecular Function	GO:0005096	GTPase activator activity	MYO9B	IDA		Human	PMID:9490638
Molecular Function	GO:0005096	GTPase activator activity	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Molecular Function	GO:0005096	GTPase activator activity	Myo9b	IDA		Mouse	PMID:17314409
Molecular Function	GO:0005096	GTPase activator activity	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Molecular Function	GO:0005096	GTPase activator activity	Myo9b	IMP		Rat	PMID:9348541|RGD:1581711
Molecular Function	GO:0000146	microfilament motor activity	MYO9B	IDA		Human	PMID:11901422
Molecular Function	GO:0000146	microfilament motor activity	MYO9B	IDA		Human	PMID:16338935
Molecular Function	GO:0000146	microfilament motor activity	MYO9B	IDA		Human	PMID:16616011
Molecular Function	GO:0000146	microfilament motor activity	MYO9B	IDA		Human	PMID:9490638
Molecular Function	GO:0000146	microfilament motor activity	Myo9b	IDA		Mouse	PMID:17314409
Molecular Function	GO:0000146	microfilament motor activity	Myo9b	IDA		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0000146	microfilament motor activity	Myo9b	IMP		Rat	PMID:16179355|RGD:1581655
Molecular Function	GO:0005515	protein binding	MYO9B	IPI	UniProtKB:P61586	Human	PMID:15644318
Molecular Function	GO:0005515	protein binding	MYO9B	IPI	UniProtKB:Q9Y6D6	Human	PMID:15644318
Molecular Function	GO:0005515	protein binding	MYO9B	IPI	UniProtKB:P55160	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	Myo9b	IPI	RGD:1560793	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0005515	protein binding	Myo9b	IPI	UniProtKB:D4A631	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0005515	protein binding	Myo9b	IPI	UniProtKB:Q7TSU1	Rat	PMID:15644318|RGD:1579801
Molecular Function	GO:0048495	Roundabout binding	MYO9B	IPI	UniProtKB:Q9Y6N7	Human	PMID:26529257
Molecular Function	GO:0031267	small GTPase binding	MYO9B	IPI	UniProtKB:P61586	Human	PMID:26529257
Molecular Function	GO:0008270	zinc ion binding	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Cellular Component	GO:0005884	actin filament	MYO9B	IDA		Human	PMID:16338935
Cellular Component	GO:0005884	actin filament	MYO9B	IDA		Human	PMID:16616011
Cellular Component	GO:0005884	actin filament	MYO9B	IDA		Human	PMID:8907710
Cellular Component	GO:0005884	actin filament	Myo9b	IDA		Rat	PMID:9348541|RGD:1581711
Cellular Component	GO:0005938	cell cortex	MYO9B	IDA		Human	PMID:8907710
Cellular Component	GO:0005737	cytoplasm	MYO9B	IDA		Human	PMID:8907710
Cellular Component	GO:0005737	cytoplasm	Myo9b	IDA		Rat	PMID:9348541|RGD:1581711
Cellular Component	GO:0005829	cytosol	MYO9B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032433	filopodium tip	Myo9b	IDA		Mouse	PMID:17314409
Cellular Component	GO:0030027	lamellipodium	Myo9b	IDA		Mouse	PMID:17314409
Cellular Component	GO:0030027	lamellipodium	Myo9b	IDA		Rat	PMID:9348541|RGD:1581711
Cellular Component	GO:0016020	membrane	MYO9B	HDA		Human	PMID:19946888
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MYO9B	IDA		Human	PMID:8907710
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Myo9b	IDA		Rat	PMID:9348541|RGD:1581711
Cellular Component	GO:0001726	ruffle	Myo9b	IDA		Rat	PMID:9348541|RGD:1581711
Biological Process	GO:0030048	actin filament-based movement	MYO9B	IDA		Human	PMID:11901422
Biological Process	GO:0030048	actin filament-based movement	MYO9B	IDA		Human	PMID:16338935
Biological Process	GO:0030048	actin filament-based movement	MYO9B	IDA		Human	PMID:9490638
Biological Process	GO:0030010	establishment of cell polarity	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0072673	lamellipodium morphogenesis	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0048246	macrophage chemotaxis	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0002548	monocyte chemotaxis	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0043547	positive regulation of GTPase activity	Myo9b	IDA		Mouse	PMID:17314409
Biological Process	GO:0043547	positive regulation of GTPase activity	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0035023	regulation of Rho protein signal transduction	MYO9B	IMP		Human	PMID:26529257
Biological Process	GO:0007266	Rho protein signal transduction	Myo9b	IMP	MGI:MGI:4867915	Mouse	PMID:20566876
Biological Process	GO:0007266	Rho protein signal transduction	Myo9b	IDA		Rat	PMID:7882973|RGD:633447
Biological Process	GO:0035385	Roundabout signaling pathway	MYO9B	IDA		Human	PMID:26529257

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern