Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYOZ2
  • Mouse genes Myoz2
  • Rat genes Myoz2
  • Zfish genes myoz2a,myoz2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myoz2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Myoz2	IPI	PR:Q9JI91	Mouse	PMID:11114196
Molecular Function	GO:0003779	actin binding	Myoz2	IPI	PR:O88990	Mouse	PMID:11114196
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O75112	Human	PMID:10427098
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q08209	Human	PMID:11114196
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P35609	Human	PMID:11842093
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O15273	Human	PMID:15582318
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q9UBF9	Human	PMID:16076904
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:19447967
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P12814	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P35609	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q6PGQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P12814	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P35609	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P35609	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:O43707	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P12814	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q9NZC7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q14957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYOZ2	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0031433	telethonin binding	MYOZ2	IPI	UniProtKB:O15273	Human	PMID:15582318
Cellular Component	GO:0015629	actin cytoskeleton	Myoz2	IDA		Mouse	PMID:11114196
Cellular Component	GO:0015629	actin cytoskeleton	Myoz2	IPI	PR:O88990	Mouse	PMID:11114196
Cellular Component	GO:0015629	actin cytoskeleton	Myoz2	IPI	PR:Q9JI91	Mouse	PMID:11114196
Cellular Component	GO:0030018	Z disc	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153
Cellular Component	GO:0030018	Z disc	Myoz2	IDA		Mouse	PMID:15665106
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153
Biological Process	GO:0045214	sarcomere organization	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153
Biological Process	GO:0043503	skeletal muscle fiber adaptation	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153
Biological Process	GO:0007519	skeletal muscle tissue development	Myoz2	IDA		Mouse	MGI:MGI:3513659|PMID:15543153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern