Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYRF
  • Mouse genes Myrf
  • Rat genes Myrf
  • Zfish genes myrf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myrf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Myrf	IDA		Mouse	MGI:MGI:5544144|PMID:24204311
Molecular Function	GO:0003677	DNA binding	Myrf	IDA		Mouse	MGI:MGI:6316519|PMID:28441531
Molecular Function	GO:0003677	DNA binding	Myrf	IDA		Mouse	MGI:MGI:5805298|PMID:27532821
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myrf	IDA		Mouse	MGI:MGI:5544144|PMID:24204311
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myrf	IDA		Mouse	MGI:MGI:5805298|PMID:27532821
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Myrf	IDA		Mouse	MGI:MGI:6450350|PMID:31828317
Molecular Function	GO:0005515	protein binding	Myrf	IPI	UniProtKB:Q91X86	Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0005737	cytoplasm	Myrf	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0005829	cytosol	MYRF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Myrf	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0005794	Golgi apparatus	MYRF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MYRF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Myrf	IDA		Mouse	MGI:MGI:6316519|PMID:28441531
Cellular Component	GO:0005634	nucleus	Myrf	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Cellular Component	GO:0005634	nucleus	Myrf	IDA		Mouse	MGI:MGI:3850982|PMID:19596243
Biological Process	GO:0032286	central nervous system myelin maintenance	Myrf	IMP		Mouse	MGI:MGI:5437779|PMID:22956843
Biological Process	GO:0022010	central nervous system myelination	Myrf	IMP		Mouse	MGI:MGI:5544144|PMID:24204311
Biological Process	GO:0022010	central nervous system myelination	Myrf	IMP		Mouse	MGI:MGI:5805298|PMID:27532821
Biological Process	GO:0022010	central nervous system myelination	Myrf	IMP		Mouse	MGI:MGI:3850982|PMID:19596243
Biological Process	GO:0014003	oligodendrocyte development	Myrf	IMP		Mouse	MGI:MGI:5544144|PMID:24204311
Biological Process	GO:0014003	oligodendrocyte development	Myrf	IMP		Mouse	MGI:MGI:5805298|PMID:27532821
Biological Process	GO:0014003	oligodendrocyte development	Myrf	IMP		Mouse	MGI:MGI:3850982|PMID:19596243
Biological Process	GO:0014003	oligodendrocyte development	Myrf	IDA		Mouse	MGI:MGI:6450350|PMID:31828317
Biological Process	GO:0048709	oligodendrocyte differentiation	Myrf	IMP		Mouse	MGI:MGI:5805298|PMID:27532821
Biological Process	GO:0048709	oligodendrocyte differentiation	Myrf	IMP		Mouse	MGI:MGI:5544144|PMID:24204311
Biological Process	GO:0048709	oligodendrocyte differentiation	Myrf	IMP		Mouse	MGI:MGI:5437779|PMID:22956843
Biological Process	GO:0048709	oligodendrocyte differentiation	Myrf	IMP		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myrf	IDA		Mouse	MGI:MGI:5805298|PMID:27532821
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myrf	IDA		Mouse	MGI:MGI:3850982|PMID:19596243
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myrf	IMP		Mouse	MGI:MGI:5437779|PMID:22956843
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Myrf	IDA		Mouse	MGI:MGI:5544144|PMID:24204311
Biological Process	GO:0031643	positive regulation of myelination	Myrf	IMP		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0031643	positive regulation of myelination	Myrf	IMP		Mouse	MGI:MGI:3850982|PMID:19596243
Biological Process	GO:0016540	protein autoprocessing	Myrf	IDA		Mouse	MGI:MGI:6258499|PMID:30249802
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Myrf	IDA		Mouse	MGI:MGI:6450350|PMID:31828317

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern