Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYT1L
  • Mouse genes Myt1l
  • Rat genes Myt1l
  • Zfish genes myt1la,myt1lb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myt1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050897	cobalt ion binding	Myt1l	IMP		Rat	PMID:10606515|RGD:12793025
Molecular Function	GO:0003677	DNA binding	Myt1l	IDA		Rat	PMID:10606515|RGD:12793025
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Myt1l	IDA		Rat	PMID:8631881|RGD:633486
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Myt1l	IMP		Rat	PMID:8631881|RGD:633486
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Molecular Function	GO:0043167	ion binding	Myt1l	EXP		Rat	PMID:10606515|RGD:12793025
Molecular Function	GO:0043167	ion binding	Myt1l	IDA		Rat	PMID:10606515|RGD:12793025
Molecular Function	GO:0005515	protein binding	Myt1l	IPI	UniProtKB:Q62141	Mouse	MGI:MGI:5897487|PMID:28379941
Molecular Function	GO:0005515	protein binding	Myt1l	IPI	PR:Q62141-3	Mouse	PMID:15935060
Molecular Function	GO:0005515	protein binding	Myt1l	IPI	PR:Q62141-2	Mouse	PMID:15935060
Molecular Function	GO:0044323	retinoic acid-responsive element binding	Myt1l	IMP		Rat	PMID:10606515|RGD:12793025
Molecular Function	GO:0044323	retinoic acid-responsive element binding	Myt1l	IDA		Rat	PMID:8631881|RGD:633486
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Myt1l	IMP		Rat	PMID:8631881|RGD:633486
Molecular Function	GO:0003713	transcription coactivator activity	Myt1l	IDA		Rat	PMID:8631881|RGD:633486
Molecular Function	GO:0008270	zinc ion binding	Myt1l	IMP		Rat	PMID:10606515|RGD:12793025
Cellular Component	GO:0005634	nucleus	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Cellular Component	GO:0005634	nucleus	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Cellular Component	GO:0005634	nucleus	Myt1l	IDA		Mouse	PMID:9373037
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0007399	nervous system development	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0007399	nervous system development	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048666	neuron development	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0048666	neuron development	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0030182	neuron differentiation	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0030182	neuron differentiation	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0048663	neuron fate commitment	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048663	neuron fate commitment	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0048665	neuron fate specification	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048665	neuron fate specification	Myt1l	IDA		Mouse	MGI:MGI:5897487|PMID:28379941
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Myt1l	IDA		Rat	PMID:8631881|RGD:633486
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Myt1l	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0051238	sequestering of metal ion	Myt1l	EXP		Rat	PMID:10606515|RGD:12793025
Biological Process	GO:0051238	sequestering of metal ion	Myt1l	IDA		Rat	PMID:10606515|RGD:12793025

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern