Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MZF1
  • Mouse genes Mzf1
  • Rat genes Mzf1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mzf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MZF1	IDA		Human	PMID:7579328
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MZF1	IDA		Human	PMID:7579328
Molecular Function	GO:0005515	protein binding	MZF1	IPI	UniProtKB:Q9NZG6	Human	PMID:10777584
Molecular Function	GO:0042803	protein homodimerization activity	MZF1	IPI	UniProtKB:P28698	Human	PMID:16950398
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MZF1	IDA		Human	PMID:7579328
Molecular Function	GO:0000976	transcription cis-regulatory region binding	MZF1	IDA		Human	PMID:15541732
Cellular Component	GO:0005654	nucleoplasm	MZF1	IDA		Human	GO_REF:0000052
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MZF1	IDA		Human	PMID:7579328
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MZF1	IDA		Human	PMID:7579328
Biological Process	GO:0006355	regulation of DNA-templated transcription	MZF1	IDA		Human	PMID:15541732

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern