Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NAE1
  • Mouse genes Nae1
  • Rat genes Nae1
  • Zfish genes nae1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nae1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019781	NEDD8 activating enzyme activity	NAE1	IDA		Human	PMID:12740388
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:Q8TBC4	Human	PMID:10722740
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:Q13625	Human	PMID:12694406
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:P05067	Human	PMID:14557245
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:P61081	Human	PMID:15361859
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:Q8TBC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NAE1	IPI	UniProtKB:P05067	Human	PMID:8626687
Molecular Function	GO:0046982	protein heterodimerization activity	NAE1	IPI	UniProtKB:Q8TBC4	Human	PMID:12740388
Molecular Function	GO:0031625	ubiquitin protein ligase binding	NAE1	IPI	UniProtKB:Q14669	Human	PMID:18627766
Cellular Component	GO:0005769	early endosome	Nae1	IDA		Rat	PMID:17611268|RGD:13801047
Cellular Component	GO:0045121	membrane raft	Nae1	IDA		Rat	PMID:14557245|RGD:2302388
Cellular Component	GO:0032991	protein-containing complex	NAE1	IDA		Human	PMID:12740388
Biological Process	GO:0033314	mitotic DNA replication checkpoint signaling	NAE1	IDA		Human	PMID:10722740
Biological Process	GO:0051402	neuron apoptotic process	NAE1	IDA		Human	PMID:14557245
Biological Process	GO:0045116	protein neddylation	NAE1	IDA		Human	PMID:10207026
Biological Process	GO:0045116	protein neddylation	NAE1	IDA		Human	PMID:12740388
Biological Process	GO:0042981	regulation of apoptotic process	NAE1	IMP		Human	PMID:10722740
Biological Process	GO:0042981	regulation of apoptotic process	NAE1	IDA		Human	PMID:14557245
Biological Process	GO:0043523	regulation of neuron apoptotic process	NAE1	IDA		Human	PMID:10722740

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern