Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NAGLU
  • Mouse genes Naglu
  • Rat genes Naglu
  • Zfish genes naglu
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Naglu

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004561	alpha-N-acetylglucosaminidase activity	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:10588735
Cellular Component	GO:0070062	extracellular exosome	NAGLU	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	NAGLU	IDA		Human	PMID:21082674
Cellular Component	GO:0070062	extracellular exosome	NAGLU	HDA		Human	PMID:23533145
Cellular Component	GO:0043202	lysosomal lumen	Naglu	IDA		Mouse	PMID:15537895
Cellular Component	GO:0005773	vacuole	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0030534	adult behavior	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0030534	adult behavior	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0042982	amyloid precursor protein metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25267636
Biological Process	GO:0035904	aorta development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:32428018
Biological Process	GO:0035909	aorta morphogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0048143	astrocyte activation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0048708	astrocyte differentiation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:12111813
Biological Process	GO:0006914	autophagy	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0006914	autophagy	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0055013	cardiac muscle cell development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0044242	cellular lipid catabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0071407	cellular response to organic cyclic compound	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21037080
Biological Process	GO:0071310	cellular response to organic substance	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19632871
Biological Process	GO:0034599	cellular response to oxidative stress	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:0032963	collagen metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:1904390	cone retinal bipolar cell differentiation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0007028	cytoplasm organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19416848
Biological Process	GO:0008340	determination of adult lifespan	Naglu	IGI	MGI:MGI:1350341	Mouse	PMID:22867887
Biological Process	GO:0008340	determination of adult lifespan	Naglu	IGI	MGI:MGI:1342057	Mouse	PMID:22867887
Biological Process	GO:0008340	determination of adult lifespan	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0008340	determination of adult lifespan	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0008340	determination of adult lifespan	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0003158	endothelium development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21408219
Biological Process	GO:0035640	exploration behavior	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21635693
Biological Process	GO:0001573	ganglioside metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21408219
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:12111813
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18325808
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18509511
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19416848
Biological Process	GO:0010467	gene expression	Naglu	IDA		Mouse	PMID:19386237
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19386237
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0010467	gene expression	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0009100	glycoprotein metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25267636
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19632871
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29180785
Biological Process	GO:0007030	Golgi organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21037080
Biological Process	GO:0031069	hair follicle morphogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19632871
Biological Process	GO:0007507	heart development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0003170	heart valve development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:10588735
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	Naglu	IDA		Mouse	PMID:15649123
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18509511
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0030202	heparin metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:12111813
Biological Process	GO:0030202	heparin metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25267636
Biological Process	GO:0030202	heparin metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0042445	hormone metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0006954	inflammatory response	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18509511
Biological Process	GO:0006954	inflammatory response	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0006954	inflammatory response	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0060119	inner ear receptor cell development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:0003220	left ventricular cardiac muscle tissue morphogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0060173	limb development	Naglu	IGI	MGI:MGI:1342057	Mouse	PMID:22867887
Biological Process	GO:0001889	liver development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19632871
Biological Process	GO:0045475	locomotor rhythm	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:0007626	locomotory behavior	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21635693
Biological Process	GO:0007040	lysosome organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19632871
Biological Process	GO:0007040	lysosome organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25524704
Biological Process	GO:0007040	lysosome organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0007040	lysosome organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:0035633	maintenance of blood-brain barrier	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21408219
Biological Process	GO:0014004	microglia differentiation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18509511
Biological Process	GO:0001774	microglial cell activation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0042474	middle ear morphogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:0003183	mitral valve morphogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0061744	motor behavior	Naglu	IGI	MGI:MGI:1350341	Mouse	PMID:22867887
Biological Process	GO:0061744	motor behavior	Naglu	IGI	MGI:MGI:1342057	Mouse	PMID:22867887
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0021675	nerve development	Naglu	IGI	MGI:MGI:1342057	Mouse	PMID:22867887
Biological Process	GO:0022008	neurogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:12111813
Biological Process	GO:0022008	neurogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18509511
Biological Process	GO:0022008	neurogenesis	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0150076	neuroinflammatory response	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19386237
Biological Process	GO:0019538	protein metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17185018
Biological Process	GO:0019538	protein metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25267636
Biological Process	GO:0018158	protein oxidation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0016485	protein processing	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:18325808
Biological Process	GO:0006029	proteoglycan metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:25267636
Biological Process	GO:0097696	receptor signaling pathway via STAT	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0034285	response to disaccharide	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0032496	response to lipopolysaccharide	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0009611	response to wounding	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:12111813
Biological Process	GO:0060041	retina development in camera-type eye	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0046548	retinal rod cell development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:17712420
Biological Process	GO:1904389	rod bipolar cell differentiation	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0097577	sequestering of iron ion	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0006801	superoxide metabolic process	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:19409882
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:29624734
Biological Process	GO:0007033	vacuole organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21408219
Biological Process	GO:0007033	vacuole organization	Naglu	IGI	MGI:MGI:1342057	Mouse	PMID:22867887
Biological Process	GO:0007033	vacuole organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26147524
Biological Process	GO:0007033	vacuole organization	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:26607664
Biological Process	GO:0001944	vasculature development	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21408219
Biological Process	GO:0099022	vesicle tethering	Naglu	IMP	MGI:MGI:1934018	Mouse	PMID:21037080

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern