Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NANOS3
  • Mouse genes Nanos3
  • Rat genes Nanos3
  • Zfish genes nanos3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nanos3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NANOS3	IPI	UniProtKB:A5YKK6	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	NANOS3	IPI	UniProtKB:O75175	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	Nanos3	IPI	UniProtKB:Q80U58	Mouse	MGI:MGI:3772433|PMID:18089289
Molecular Function	GO:0003723	RNA binding	Nanos3	IDA		Mouse	MGI:MGI:3772433|PMID:18089289
Molecular Function	GO:0003727	single-stranded RNA binding	nanos3	IDA		Zfish	PMID:20948543
Cellular Component	GO:0005737	cytoplasm	NANOS3	IDA		Human	PMID:21421998
Cellular Component	GO:0005737	cytoplasm	Nanos3	IDA		Mouse	MGI:MGI:5009753|PMID:21421998
Cellular Component	GO:0005737	cytoplasm	Nanos3	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0005737	cytoplasm	nanos3	IDA		Zfish	PMID:11691838
Cellular Component	GO:0010494	cytoplasmic stress granule	Nanos3	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0005829	cytosol	NANOS3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NANOS3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NANOS3	IDA		Human	PMID:21421998
Cellular Component	GO:0005634	nucleus	Nanos3	IDA		Mouse	MGI:MGI:5009753|PMID:21421998
Cellular Component	GO:0005634	nucleus	Nanos3	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0043186	P granule	nanos3	IDA		Zfish	PMID:11691838
Cellular Component	GO:0000932	P-body	Nanos3	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0048471	perinuclear region of cytoplasm	NANOS3	IDA		Human	PMID:22899867
Biological Process	GO:0097190	apoptotic signaling pathway	Nanos3	IGI	MGI:MGI:99702	Mouse	PMID:18436203
Biological Process	GO:0097190	apoptotic signaling pathway	Nanos3	IMP	MGI:MGI:2682607	Mouse	PMID:18436203
Biological Process	GO:0007292	female gamete generation	nanos3	IMP	ZFIN:ZDB-GENO-070706-3	Zfish	PMID:17418113
Biological Process	GO:0036099	female germ-line stem cell population maintenance	nanos3	IMP	ZFIN:ZDB-GENO-130314-6	Zfish	PMID:23228893
Biological Process	GO:0007281	germ cell development	NANOS3	IMP		Human	PMID:21421998
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Nanos3	IMP	MGI:MGI:2682607	Mouse	PMID:18436203
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Nanos3	IGI	MGI:MGI:99702	Mouse	PMID:18436203
Biological Process	GO:0017148	negative regulation of translation	NANOS3	IDA		Human	PMID:24736845
Biological Process	GO:0001555	oocyte growth	nanos3	IMP	ZFIN:ZDB-GENO-070706-3	Zfish	PMID:17418113
Biological Process	GO:0048477	oogenesis	Nanos3	IMP	MGI:MGI:2682607	Mouse	PMID:12947200
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	NANOS3	IDA		Human	PMID:24736845
Biological Process	GO:0051726	regulation of cell cycle	Nanos3	IDA		Mouse	MGI:MGI:3772433|PMID:18089289
Biological Process	GO:0006417	regulation of translation	Nanos3	IEP		Mouse	MGI:MGI:3772433|PMID:18089289
Biological Process	GO:0007283	spermatogenesis	Nanos3	IDA		Mouse	MGI:MGI:3772433|PMID:18089289
Biological Process	GO:0007283	spermatogenesis	Nanos3	IMP	MGI:MGI:2682607	Mouse	PMID:12947200

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern