Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NAT8,NAT8B
  • Mouse genes Nat8
  • Rat genes Nat8
  • Zfish genes nat8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nat8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047198	cysteine-S-conjugate N-acetyltransferase activity	NAT8	IDA		Human	PMID:20392701
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8	IDA		Human	PMID:19011241
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8	IDA		Human	PMID:24556617
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8B	IDA		Human	PMID:19011241
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	NAT8B	IDA		Human	PMID:24556617
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:P56817	Human	PMID:19011241
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:O43490	Human	PMID:24556617
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:O15342	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q12999	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q6ZVE7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q96AN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9BSR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9HDC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAT8B	IPI	UniProtKB:P56817	Human	PMID:19011241
Molecular Function	GO:0005515	protein binding	NAT8B	IPI	UniProtKB:O43490	Human	PMID:24556617
Cellular Component	GO:0005783	endoplasmic reticulum	NAT8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	NAT8	IDA		Human	PMID:20392701
Cellular Component	GO:0005789	endoplasmic reticulum membrane	NAT8B	IDA		Human	PMID:19011241
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	NAT8	IDA		Human	PMID:24556617
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	NAT8B	IDA		Human	PMID:24556617
Cellular Component	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	NAT8	IDA		Human	PMID:19011241
Cellular Component	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	NAT8B	IDA		Human	PMID:19011241
Cellular Component	GO:0016020	membrane	NAT8	IDA		Human	PMID:20392701
Biological Process	GO:0050435	amyloid-beta metabolic process	NAT8B	IMP		Human	PMID:19011241
Biological Process	GO:0003401	axis elongation	nat8	IMP	ZFIN:ZDB-MRPHLNO-141125-2	Zfish	PMID:25123547
Biological Process	GO:0003401	axis elongation	nat8	IMP	ZFIN:ZDB-MRPHLNO-141125-1	Zfish	PMID:25123547
Biological Process	GO:0043009	chordate embryonic development	nat8	IMP	ZFIN:ZDB-MRPHLNO-141125-1	Zfish	PMID:25123547
Biological Process	GO:0043009	chordate embryonic development	nat8	IMP	ZFIN:ZDB-MRPHLNO-141125-2	Zfish	PMID:25123547
Biological Process	GO:0001702	gastrulation with mouth forming second	Nat8	IMP		Mouse	MGI:MGI:2135831|PMID:11397015
Biological Process	GO:0043066	negative regulation of apoptotic process	NAT8B	IDA		Human	PMID:24556617
Biological Process	GO:0018003	peptidyl-lysine N6-acetylation	NAT8	IDA		Human	PMID:19011241
Biological Process	GO:0018003	peptidyl-lysine N6-acetylation	NAT8	IDA		Human	PMID:24556617
Biological Process	GO:0018003	peptidyl-lysine N6-acetylation	NAT8B	IDA		Human	PMID:19011241
Biological Process	GO:0018003	peptidyl-lysine N6-acetylation	NAT8B	IDA		Human	PMID:24556617
Biological Process	GO:0010628	positive regulation of gene expression	NAT8	IMP		Human	PMID:19011241
Biological Process	GO:0010628	positive regulation of gene expression	NAT8	IMP		Human	PMID:24556617
Biological Process	GO:0010628	positive regulation of gene expression	NAT8B	IMP		Human	PMID:19011241
Biological Process	GO:0010628	positive regulation of gene expression	NAT8B	IMP		Human	PMID:24556617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern