Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MICOS10-NBL1,NBL1
  • Mouse genes Nbl1
  • Rat genes Nbl1
  • Zfish genes nbl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nbl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036122	BMP binding	Nbl1	IDA		Mouse	MGI:MGI:1203284|PMID:9660951
Molecular Function	GO:0042802	identical protein binding	NBL1	IMP		Human	PMID:23063586
Molecular Function	GO:0016015	morphogen activity	Nbl1	IDA		Mouse	MGI:MGI:1203284|PMID:9660951
Molecular Function	GO:0005515	protein binding	NBL1	IPI	UniProtKB:P62166	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NBL1	IPI	UniProtKB:Q8NF64-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NBL1	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NBL1	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Nbl1	IPI	UniProtKB:O88279|UniProtKB:Q9WVC1	Mouse	MGI:MGI:5318030|PMID:15528323
Cellular Component	GO:0005615	extracellular space	NBL1	IDA		Human	PMID:11594460
Biological Process	GO:0048263	determination of dorsal identity	Nbl1	IMP		Mouse	MGI:MGI:1203284|PMID:9660951
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	NBL1	IDA		Human	PMID:23063586
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	NBL1	IMP		Human	PMID:25561725
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Nbl1	IDA		Mouse	PMID:23676271
Biological Process	GO:0090027	negative regulation of monocyte chemotaxis	Nbl1	IDA		Mouse	MGI:MGI:5318030|PMID:15528323
Biological Process	GO:0007399	nervous system development	Nbl1	IMP		Mouse	MGI:MGI:1203284|PMID:9660951
Biological Process	GO:0030182	neuron differentiation	Nbl1	IDA		Mouse	PMID:16325379
Biological Process	GO:0048812	neuron projection morphogenesis	Nbl1	IDA		Mouse	PMID:16325379
Biological Process	GO:0045666	positive regulation of neuron differentiation	Nbl1	IDA		Mouse	PMID:16325379
Biological Process	GO:0060872	semicircular canal development	nbl1	IMP	ZFIN:ZDB-MRPHLNO-090818-9	Zfish	PMID:19320994
Biological Process	GO:0060872	semicircular canal development	nbl1	IMP	ZFIN:ZDB-MRPHLNO-090818-8	Zfish	PMID:19320994
Biological Process	GO:0060876	semicircular canal formation	nbl1	IMP	ZFIN:ZDB-MRPHLNO-090818-8	Zfish	PMID:21129728
Biological Process	GO:0038098	sequestering of BMP from receptor via BMP binding	NBL1	IDA		Human	PMID:23063586
Biological Process	GO:0035582	sequestering of BMP in extracellular matrix	Nbl1	IDA		Mouse	MGI:MGI:1203284|PMID:9660951

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern