Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NBR1
  • Mouse genes Nbr1
  • Rat genes Nbr1
  • Zfish genes nbr1a,nbr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nbr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Nbr1	IDA		Mouse	MGI:MGI:4818844|PMID:20616007
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:O95166	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P38182	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P60520	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q13501	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9BXW4	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9GZQ8	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9H0R8	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9H492	Human	PMID:19250911
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P0CG48	Human	PMID:19427866
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P40818	Human	PMID:19427866
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9H492	Human	PMID:19427866
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q7Z698	Human	PMID:19822672
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q924S7	Human	PMID:19822672
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P38182	Human	PMID:20010802
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P49840	Human	PMID:20368287
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P42858	Human	PMID:20417604
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:O95166	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q13501	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9BXW4	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9H0R8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q13501	Human	PMID:20808283
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:O95166	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P0CG48	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P49840	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P49841	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q13501	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9GZQ8	Human	PMID:24879152
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:Q9H2B2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P49841	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	NBR1	IPI	UniProtKB:P49840	Human	PMID:30824926
Molecular Function	GO:0005515	protein binding	Nbr1	IPI	UniProtKB:Q9GZQ8	Mouse	MGI:MGI:3837054|PMID:19250911
Molecular Function	GO:0043130	ubiquitin binding	NBR1	IDA		Human	PMID:19427866
Cellular Component	GO:0005776	autophagosome	Nbr1	IDA		Mouse	MGI:MGI:4818844|PMID:20616007
Cellular Component	GO:0005829	cytosol	NBR1	IDA		Human	PMID:19250911
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NBR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	Nbr1	IDA		Mouse	MGI:MGI:3837054|PMID:19250911
Cellular Component	GO:0016020	membrane	NBR1	HDA		Human	PMID:19946888
Cellular Component	GO:0005758	mitochondrial intermembrane space	Nbr1	IDA		Mouse	PMID:25002142
Cellular Component	GO:0005739	mitochondrion	NBR1	IDA		Human	PMID:21296869
Cellular Component	GO:0016604	nuclear body	NBR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NBR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000407	phagophore assembly site	Nbr1	IDA		Mouse	PMID:21220506
Cellular Component	GO:0043235	receptor complex	NBR1	IDA		Human	PMID:19250911
Biological Process	GO:0016236	macroautophagy	NBR1	IDA		Human	PMID:19250911
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Nbr1	IMP		Mouse	MGI:MGI:4818844|PMID:20616007
Biological Process	GO:0030500	regulation of bone mineralization	Nbr1	IMP		Mouse	MGI:MGI:4818844|PMID:20616007
Biological Process	GO:0032872	regulation of stress-activated MAPK cascade	Nbr1	IMP		Mouse	MGI:MGI:4818844|PMID:20616007

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern