Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ncam1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NCAM1
- Mouse genes Ncam1
- Rat genes Ncam1
- Zfish genes ncam1a,ncam1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ncam1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030275	LRR domain binding	Ncam1	IPI	RGD:2116	Rat	PMID:15865439\|RGD:1578371
Molecular Function	GO:0019902	phosphatase binding	Ncam1	IDA		Rat	PMID:15865439\|RGD:1578371
Molecular Function	GO:0005515	protein binding	NCAM1	IPI	UniProtKB:P25098	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NCAM1	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	UniProtKB:P21741	Mouse	MGI:MGI:6294421\|PMID:10772929
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	PR:Q52KR2	Mouse	PMID:26651291
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	PR:O35382	Mouse	PMID:21389209
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	PR:O35250	Mouse	PMID:21389209
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	RGD:2517	Rat	PMID:15865439\|RGD:1578371
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	UniProtKB:P16092	Rat	PMID:16709412\|RGD:8553755
Molecular Function	GO:0005515	protein binding	Ncam1	IPI	UniProtKB:Q63237	Rat	PMID:16709412\|RGD:8553755
Molecular Function	GO:0005515	protein binding	ncam1a	IPI	UniProtKB:Q5J1R9	Zfish	PMID:18296487
Cellular Component	GO:0030424	axon	Ncam1	IDA		Mouse	PMID:24582971
Cellular Component	GO:0030424	axon	Ncam1	IDA		Mouse	PMID:15964824
Cellular Component	GO:0030424	axon	Ncam1	IDA		Mouse	PMID:15738425
Cellular Component	GO:0030424	axon	Ncam1	IDA		Mouse	PMID:15065125
Cellular Component	GO:0009986	cell surface	NCAM1	IDA		Human	PMID:10766765
Cellular Component	GO:0005911	cell-cell junction	Ncam1	IDA		Mouse	PMID:23284756
Cellular Component	GO:0062023	collagen-containing extracellular matrix	NCAM1	HDA		Human	PMID:27559042
Cellular Component	GO:0005829	cytosol	NCAM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	NCAM1	IDA		Human	PMID:17213291
Cellular Component	GO:0009897	external side of plasma membrane	Ncam1	IDA		Mouse	PMID:21708977
Cellular Component	GO:0009897	external side of plasma membrane	Ncam1	IDA		Mouse	PMID:7613634
Cellular Component	GO:0009897	external side of plasma membrane	Ncam1	IDA		Mouse	PMID:17213291
Cellular Component	GO:0098978	glutamatergic synapse	Ncam1	IDA		Rat	PMID:2592994\|RGD:13702176
Cellular Component	GO:0030426	growth cone	Ncam1	IDA		Mouse	PMID:21389209
Cellular Component	GO:0016020	membrane	NCAM1	HDA		Human	PMID:19946888
Cellular Component	GO:0043209	myelin sheath	Ncam1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0043025	neuronal cell body	Ncam1	IDA		Mouse	PMID:15065125
Cellular Component	GO:0043025	neuronal cell body	Ncam1	IDA		Rat	PMID:16216431\|RGD:2326008
Cellular Component	GO:0005886	plasma membrane	NCAM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ncam1	IDA		Rat	PMID:2723399\|RGD:40924669
Cellular Component	GO:0045211	postsynaptic membrane	Ncam1	IDA		Rat	PMID:2592994\|RGD:13702176
Cellular Component	GO:0042734	presynaptic membrane	Ncam1	IDA		Rat	PMID:2592994\|RGD:13702176
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ncam1	IDA		Rat	PMID:7997264\|RGD:13702438
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ncam1	IMP		Rat	PMID:7997264\|RGD:13702438
Biological Process	GO:0007568	aging	Ncam1	IDA		Rat	PMID:17904697\|RGD:2326009
Biological Process	GO:0031100	animal organ regeneration	Ncam1	IEP		Rat	PMID:16609270\|RGD:2326001
Biological Process	GO:0007411	axon guidance	ncam1b	IMP	ZFIN:ZDB-MRPHLNO-120910-3	Zfish	PMID:21890892
Biological Process	GO:0007413	axonal fasciculation	Ncam1	IMP		Rat	PMID:3856258\|RGD:11570517
Biological Process	GO:0007420	brain development	Ncam1	IEP		Rat	PMID:10936176\|RGD:40924671
Biological Process	GO:0019722	calcium-mediated signaling	Ncam1	IDA		Mouse	PMID:7613634
Biological Process	GO:0007166	cell surface receptor signaling pathway	Ncam1	IDA		Mouse	PMID:7613634
Biological Process	GO:0071241	cellular response to inorganic substance	Ncam1	IEP		Rat	PMID:17537562\|RGD:2326012
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	Ncam1	IEP		Rat	PMID:19853610\|RGD:2325979
Biological Process	GO:0071679	commissural neuron axon guidance	Ncam1	IGI	UniProtKB:P48540	Mouse	MGI:MGI:5440338\|PMID:22998873
Biological Process	GO:0034109	homotypic cell-cell adhesion	Ncam1	IMP		Mouse	PMID:7613634
Biological Process	GO:0007611	learning or memory	Ncam1	IMP		Rat	PMID:18194217\|RGD:2326018
Biological Process	GO:0007611	learning or memory	Ncam1	IDA		Rat	PMID:18702715\|RGD:2326027
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ncam1	IDA		Rat	PMID:7997264\|RGD:13702438
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ncam1	IMP		Rat	PMID:7997264\|RGD:13702438
Biological Process	GO:0033555	multicellular organismal response to stress	Ncam1	IDA		Rat	PMID:17429411\|RGD:2326013
Biological Process	GO:0043069	negative regulation of programmed cell death	Ncam1	IMP		Rat	PMID:18757519\|RGD:2326023
Biological Process	GO:0048666	neuron development	Ncam1	IDA		Rat	PMID:16958105\|RGD:2326000
Biological Process	GO:0031175	neuron projection development	Ncam1	IGI	MGI:MGI:95522	Mouse	PMID:21389209
Biological Process	GO:0014012	peripheral nervous system axon regeneration	Ncam1	IEP		Rat	PMID:15679872\|RGD:2326091
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	Ncam1	IDA		Mouse	PMID:7613634
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Ncam1	IMP		Rat	PMID:19853610\|RGD:2325979
Biological Process	GO:0021961	posterior commissure morphogenesis	ncam1a	IMP	ZFIN:ZDB-MRPHLNO-120910-1	Zfish	PMID:21890892
Biological Process	GO:0001928	regulation of exocyst assembly	Ncam1	IMP		Mouse	PMID:21389209
Biological Process	GO:2001260	regulation of semaphorin-plexin signaling pathway	Ncam1	IGI	UniProtKB:P48540	Mouse	MGI:MGI:5440338\|PMID:22998873
Biological Process	GO:0051930	regulation of sensory perception of pain	Ncam1	IMP		Rat	PMID:17967506\|RGD:2326020
Biological Process	GO:0014823	response to activity	Ncam1	IEP		Rat	PMID:12499861\|RGD:11570528
Biological Process	GO:0042220	response to cocaine	Ncam1	IDA		Rat	PMID:16081054\|RGD:2325998
Biological Process	GO:0010035	response to inorganic substance	Ncam1	IEP		Rat	PMID:20412599\|RGD:2326028
Biological Process	GO:0010288	response to lead ion	Ncam1	IDA		Rat	PMID:18499259\|RGD:2326016
Biological Process	GO:0009410	response to xenobiotic stimulus	Ncam1	IDA		Rat	PMID:17307340\|RGD:2326014
Biological Process	GO:0021794	thalamus development	Ncam1	IDA		Rat	PMID:17292800\|RGD:2326015

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.