Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NCF2
  • Mouse genes Ncf2
  • Rat genes Ncf2
  • Zfish genes ncf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ncf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:11483497
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P13498	Human	PMID:11733522
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:12887891
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q05655	Human	PMID:15591124
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:15657040
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:16297854
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:16297854
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P04899	Human	PMID:16782902
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:16782902
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P62873	Human	PMID:16782902
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:16782902
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:19129478
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P27870	Human	PMID:22203994
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q08379	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q08379	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q92845	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:7938008
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:P14598	Human	PMID:8280052
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:8280052
Molecular Function	GO:0005515	protein binding	NCF2	IPI	UniProtKB:Q15080	Human	PMID:9365277
Molecular Function	GO:0005515	protein binding	Ncf2	IPI	UniProtKB:O08709	Mouse	MGI:MGI:5494778|PMID:23401562
Molecular Function	GO:0005515	protein binding	Ncf2	IPI	UniProtKB:P97369|UniProtKB:Q61093|UniProtKB:Q91Z40	Mouse	MGI:MGI:5007562|PMID:21551061
Molecular Function	GO:0005515	protein binding	Ncf2	IPI	PR:Q09014	Mouse	PMID:9490028
Molecular Function	GO:0005515	protein binding	Ncf2	IPI	UniProtKB:Q15080	Mouse	PMID:9490028
Molecular Function	GO:0005515	protein binding	Ncf2	IPI	PR:P97369	Mouse	PMID:9490028
Molecular Function	GO:0031267	small GTPase binding	Ncf2	IPI	UniProtKB:P15153	Mouse	PMID:9490028
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	Ncf2	IDA		Mouse	PMID:9490028
Molecular Function	GO:0016176	superoxide-generating NADPH oxidase activator activity	NCF2	IMP		Human	PMID:8280052
Cellular Component	GO:0001669	acrosomal vesicle	Ncf2	IDA		Mouse	PMID:15850784
Cellular Component	GO:0005737	cytoplasm	Ncf2	IDA		Mouse	PMID:15850784
Cellular Component	GO:0005737	cytoplasm	Ncf2	IDA		Rat	PMID:15722179|RGD:2314447
Cellular Component	GO:0005829	cytosol	NCF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NCF2	IDA		Human	PMID:8280052
Cellular Component	GO:0016020	membrane	NCF2	IDA		Human	PMID:8280052
Cellular Component	GO:0016020	membrane	Ncf2	IDA		Rat	PMID:15606902|RGD:2314448
Cellular Component	GO:0043020	NADPH oxidase complex	NCF2	IDA		Human	PMID:8280052
Biological Process	GO:0007568	aging	Ncf2	IEP		Rat	PMID:18386218|RGD:2292095
Biological Process	GO:0032870	cellular response to hormone stimulus	Ncf2	IDA		Rat	PMID:18298462|RGD:2314433
Biological Process	GO:0045777	positive regulation of blood pressure	Ncf2	IMP		Rat	PMID:19307699|RGD:2314430
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Ncf2	IMP		Rat	PMID:18675340|RGD:2314432
Biological Process	GO:1903426	regulation of reactive oxygen species biosynthetic process	Ncf2	IMP		Rat	PMID:27279484|RGD:151347625
Biological Process	GO:0014823	response to activity	Ncf2	IEP		Rat	PMID:17310390|RGD:2314444
Biological Process	GO:0009749	response to glucose	Ncf2	IDA		Rat	PMID:19854265|RGD:2314424
Biological Process	GO:0055093	response to hyperoxia	Ncf2	IEP		Rat	PMID:19337906|RGD:2314428
Biological Process	GO:0034616	response to laminar fluid shear stress	Ncf2	IEP		Rat	PMID:19353375|RGD:2314427
Biological Process	GO:0033993	response to lipid	Ncf2	IEP		Rat	PMID:19713964|RGD:2314426
Biological Process	GO:0032496	response to lipopolysaccharide	Ncf2	IDA		Rat	PMID:17448908|RGD:2314442
Biological Process	GO:0014070	response to organic cyclic compound	Ncf2	IDA		Rat	PMID:19854265|RGD:2314424
Biological Process	GO:0032570	response to progesterone	Ncf2	IEP		Rat	PMID:19841131|RGD:2314425
Biological Process	GO:0009410	response to xenobiotic stimulus	Ncf2	IEP		Rat	PMID:17122189|RGD:2314445
Biological Process	GO:0042554	superoxide anion generation	NCF2	IMP		Human	PMID:8280052
Biological Process	GO:0042554	superoxide anion generation	Ncf2	IDA		Mouse	PMID:9490028

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern