Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NCKAP1
  • Mouse genes Nckap1
  • Rat genes Nckap1
  • Zfish genes nckap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nckap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q8IZP0	Human	PMID:11418237
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q7L576	Human	PMID:15294869
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q7L576	Human	PMID:15296760
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q7L576	Human	PMID:19363480
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q7L576	Human	PMID:21107423
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:B1Q236,UniProtKB:Q7L576,UniProtKB:Q8WUW1,UniProtKB:Q92558,UniProtKB:Q9NYB9	Human	PMID:24439377
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q8IZP0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q8IZP0	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	NCKAP1	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nckap1	IPI	UniProtKB:Q5DU14|UniProtKB:Q6PFX7|UniProtKB:Q8BM65	Mouse	MGI:MGI:5304984|PMID:21946561
Molecular Function	GO:0005515	protein binding	Nckap1	IPI	UniProtKB:Q5DU14	Mouse	MGI:MGI:5304984|PMID:21946561
Molecular Function	GO:0005515	protein binding	Nckap1	IPI	RGD:1321736	Rat	PMID:8605018|RGD:61669
Molecular Function	GO:0005515	protein binding	nckap1	IPI	ZFIN:ZDB-GENE-080804-1	Zfish	PMID:24371087
Molecular Function	GO:0031267	small GTPase binding	NCKAP1	IDA		Human	PMID:21107423
Cellular Component	GO:0070062	extracellular exosome	NCKAP1	HDA		Human	PMID:19056867
Cellular Component	GO:0031941	filamentous actin	Nckap1	IDA		Mouse	MGI:MGI:5897521|PMID:27927633
Cellular Component	GO:0005925	focal adhesion	NCKAP1	HDA		Human	PMID:21423176
Cellular Component	GO:0030027	lamellipodium	Nckap1	IDA		Mouse	MGI:MGI:5897521|PMID:27927633
Cellular Component	GO:0030027	lamellipodium	Nckap1	IDA		Mouse	PMID:14765121
Cellular Component	GO:0098794	postsynapse	Nckap1	IEP		Mouse	PMID:24050404
Cellular Component	GO:0098794	postsynapse	Nckap1	IDA		Mouse	PMID:24050404
Cellular Component	GO:0001726	ruffle	Nckap1	IDA		Mouse	MGI:MGI:5897521|PMID:27927633
Cellular Component	GO:0031209	SCAR complex	NCKAP1	IDA		Human	PMID:21107423
Biological Process	GO:0045176	apical protein localization	Nckap1	IDA		Mouse	PMID:16831833
Biological Process	GO:0045175	basal protein localization	Nckap1	IDA		Mouse	PMID:16831833
Biological Process	GO:0042074	cell migration involved in gastrulation	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0010172	embryonic body morphogenesis	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0048617	embryonic foregut morphogenesis	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0035050	embryonic heart tube development	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0007492	endoderm development	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0007507	heart development	nckap1	IMP	ZFIN:ZDB-CRISPR-201116-5	Zfish	PMID:32368696
Biological Process	GO:0001701	in utero embryonic development	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0030032	lamellipodium assembly	Nckap1	IDA		Mouse	PMID:14765121
Biological Process	GO:0030032	lamellipodium assembly	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0008078	mesodermal cell migration	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0001843	neural tube closure	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0048812	neuron projection morphogenesis	nckap1	IMP	ZFIN:ZDB-MRPHLNO-140327-6	Zfish	PMID:24371087
Biological Process	GO:0048812	neuron projection morphogenesis	nckap1	IMP	ZFIN:ZDB-MRPHLNO-140327-4	Zfish	PMID:24371087
Biological Process	GO:0030903	notochord development	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0048570	notochord morphogenesis	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0048339	paraxial mesoderm development	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0048340	paraxial mesoderm morphogenesis	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Nckap1	IDA		Mouse	MGI:MGI:5897521|PMID:27927633
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	NCKAP1	IDA		Human	PMID:21107423
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	NCKAP1	IMP		Human	PMID:18560548
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	NCKAP1	IDA		Human	PMID:21107423
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Nckap1	IDA		Mouse	MGI:MGI:5897521|PMID:27927633
Biological Process	GO:0050821	protein stabilization	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0016601	Rac protein signal transduction	NCKAP1	IDA		Human	PMID:21107423
Biological Process	GO:0032880	regulation of protein localization	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0001756	somitogenesis	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833
Biological Process	GO:0007354	zygotic determination of anterior/posterior axis, embryo	Nckap1	IMP	MGI:MGI:3578145	Mouse	PMID:16831833

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern