Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nckap1l

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NCKAP1L
- Mouse genes Nckap1l
- Rat genes Nckap1l
- Zfish genes nckap1l
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nckap1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	NCKAP1L	IMP		Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:O14974	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:P23246	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:P31751	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:P46459	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:P98171	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q09666	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q13459	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q14457	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q15233	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q8IZP0	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q8NEB9	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q8TD16	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q9Y6D6	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:Q9Y6W5	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	NCKAP1L	IPI	UniProtKB:P42345\|UniProtKB:Q6R327\|UniProtKB:Q9Y6W5	Human	PMID:32647003
Molecular Function	GO:0030295	protein kinase activator activity	NCKAP1L	IMP		Human	PMID:16417406
Molecular Function	GO:0044877	protein-containing complex binding	NCKAP1L	IDA		Human	PMID:16417406
Molecular Function	GO:1904841	TORC2 complex binding	NCKAP1L	IDA		Human	PMID:32647003
Cellular Component	GO:0005829	cytosol	NCKAP1L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NCKAP1L	IDA		Human	PMID:16417406
Cellular Component	GO:0070062	extracellular exosome	NCKAP1L	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	NCKAP1L	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	NCKAP1L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031209	SCAR complex	NCKAP1L	IDA		Human	PMID:16417406
Cellular Component	GO:0031209	SCAR complex	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0070358	actin polymerization-dependent cell motility	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0001782	B cell homeostasis	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0050853	B cell receptor signaling pathway	NCKAP1L	IMP		Human	PMID:17875758
Biological Process	GO:0006935	chemotaxis	NCKAP1L	IDA		Human	PMID:16417406
Biological Process	GO:0030866	cortical actin cytoskeleton organization	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0030866	cortical actin cytoskeleton organization	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0030866	cortical actin cytoskeleton organization	Nckap1l	IMP		Mouse	MGI:MGI:5502518\|PMID:23424621
Biological Process	GO:0048821	erythrocyte development	NCKAP1L	IEP		Human	PMID:7643388
Biological Process	GO:0034101	erythrocyte homeostasis	Nckap1l	IMP		Mouse	MGI:MGI:5502518\|PMID:23424621
Biological Process	GO:0030011	maintenance of cell polarity	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0002262	myeloid cell homeostasis	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0043066	negative regulation of apoptotic process	NCKAP1L	IMP		Human	PMID:17875758
Biological Process	GO:0043318	negative regulation of cytotoxic T cell degranulation	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0030593	neutrophil chemotaxis	NCKAP1L	IDA		Human	PMID:16417406
Biological Process	GO:0030838	positive regulation of actin filament polymerization	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0030838	positive regulation of actin filament polymerization	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0045579	positive regulation of B cell differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0030890	positive regulation of B cell proliferation	NCKAP1L	IMP		Human	PMID:17875758
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0045588	positive regulation of gamma-delta T cell differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0002687	positive regulation of leukocyte migration	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0045621	positive regulation of lymphocyte differentiation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:1902624	positive regulation of neutrophil migration	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0042327	positive regulation of phosphorylation	NCKAP1L	IMP		Human	PMID:16417406
Biological Process	GO:0042102	positive regulation of T cell proliferation	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0042102	positive regulation of T cell proliferation	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:1904515	positive regulation of TORC2 signaling	NCKAP1L	IMP		Human	PMID:32647003
Biological Process	GO:0065003	protein-containing complex assembly	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308
Biological Process	GO:0009410	response to xenobiotic stimulus	NCKAP1L	IMP		Human	PMID:17875758
Biological Process	GO:0043029	T cell homeostasis	Nckap1l	IMP		Mouse	MGI:MGI:3818191\|PMID:19015308

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.