Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NCOA6
  • Mouse genes Ncoa6
  • Rat genes Ncoa6
  • Zfish genes ncoa6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ncoa6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ncoa6	IDA		Mouse	PMID:12446761
Molecular Function	GO:0140463	chromatin-protein adaptor activity	Ncoa6	IMP	MGI:MGI:3046462	Mouse	PMID:17021013
Molecular Function	GO:0019899	enzyme binding	NCOA6	IPI	UniProtKB:P55345	Human	PMID:12039952
Molecular Function	GO:1990226	histone methyltransferase binding	Ncoa6	IPI	PR:Q8BRH4	Mouse	PMID:17021013
Molecular Function	GO:1990226	histone methyltransferase binding	Ncoa6	IPI	PR:Q6PDK2	Mouse	PMID:17021013
Molecular Function	GO:0042802	identical protein binding	Ncoa6	IPI	RGD:620111	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0030331	nuclear estrogen receptor binding	Ncoa6	IPI	RGD:736559	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	Ncoa6	IPI	RGD:732227	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0030374	nuclear receptor coactivator activity	NCOA6	IPI	UniProtKB:Q96PK6	Human	PMID:11443112
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Ncoa6	IDA		Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	Ncoa6	IPI	RGD:733999	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	Ncoa6	IPI	RGD:736929	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	NCOA6	IDA		Human	PMID:11443112
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	Ncoa6	IPI	UniProtKB:P04625	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	Ncoa6	IPI	RGD:619561	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	Ncoa6	IPI	RGD:732638	Rat	PMID:12189208|RGD:729665
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q92793	Human	PMID:10866662
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UPN3	Human	PMID:11443112
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q8NEZ4	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q92793	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P06400	Human	PMID:14645241
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P10275	Human	PMID:14645241
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:17021013
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q8NEZ4	Human	PMID:17021013
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UMN6	Human	PMID:17021013
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:17178841
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:17925232
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q8NEZ4	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UMN6	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q12888	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q12888-1	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q8NEZ4	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UMN6	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q8NEZ4	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:Q9UBL3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P61964	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P10275	Human	PMID:33640491
Molecular Function	GO:0005515	protein binding	NCOA6	IPI	UniProtKB:P46934	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	UniProtKB:P03372	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	UniProtKB:P10827	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	UniProtKB:P10912	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	UniProtKB:P11473	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	UniProtKB:P19793	Rat	PMID:10866662|RGD:633378
Molecular Function	GO:0005515	protein binding	Ncoa6	IPI	RGD:732123	Rat	PMID:12215545|RGD:633400
Molecular Function	GO:0019904	protein domain specific binding	Ncoa6	IMP		Rat	PMID:17536006|RGD:9590132
Molecular Function	GO:0003713	transcription coactivator activity	NCOA6	IDA		Human	PMID:10567404
Molecular Function	GO:0003713	transcription coactivator activity	NCOA6	IDA		Human	PMID:11443112
Molecular Function	GO:0003713	transcription coactivator activity	Ncoa6	IDA		Mouse	PMID:10788465
Cellular Component	GO:0005829	cytosol	NCOA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035097	histone methyltransferase complex	NCOA6	IDA		Human	PMID:17500065
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NCOA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0044666	MLL3/4 complex	NCOA6	IPI		Human	PMID:23508102
Cellular Component	GO:0005654	nucleoplasm	NCOA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NCOA6	IDA		Human	PMID:11443112
Cellular Component	GO:0005634	nucleus	NCOA6	IDA		Human	PMID:17500065
Cellular Component	GO:0005634	nucleus	Ncoa6	IDA		Mouse	PMID:10788465
Cellular Component	GO:0005634	nucleus	Ncoa6	IDA		Rat	PMID:12189208|RGD:729665
Cellular Component	GO:0032991	protein-containing complex	Ncoa6	IDA		Rat	PMID:10866662|RGD:633378
Cellular Component	GO:0005667	transcription regulator complex	Ncoa6	IDA		Mouse	PMID:10681503
Biological Process	GO:0007420	brain development	Ncoa6	IMP	MGI:MGI:2450859	Mouse	PMID:12556486
Biological Process	GO:0006974	DNA damage response	NCOA6	IDA		Human	PMID:17500065
Biological Process	GO:0006352	DNA-templated transcription initiation	NCOA6	IDA		Human	PMID:10567404
Biological Process	GO:0007507	heart development	Ncoa6	IMP	MGI:MGI:2450859	Mouse	PMID:12556486
Biological Process	GO:0007507	heart development	Ncoa6	IMP	MGI:MGI:2445463	Mouse	PMID:12368298
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Ncoa6	IMP	MGI:MGI:2450859	Mouse	PMID:12556486
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Ncoa6	IMP	MGI:MGI:2445463	Mouse	PMID:12368298
Biological Process	GO:0030099	myeloid cell differentiation	NCOA6	IDA		Human	PMID:11302752
Biological Process	GO:0001541	ovarian follicle development	Ncoa6	IEP		Rat	PMID:12374465|RGD:9590129
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ncoa6	IDA		Mouse	PMID:12556486
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ncoa6	IDA		Mouse	PMID:10681503
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Ncoa6	IMP		Rat	PMID:16738321|RGD:9590126
Biological Process	GO:0002793	positive regulation of peptide secretion	Ncoa6	IMP		Rat	PMID:16738321|RGD:9590126
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NCOA6	IDA		Human	PMID:11443112
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ncoa6	IDA		Rat	PMID:10866662|RGD:633378
Biological Process	GO:0010468	regulation of gene expression	Ncoa6	IMP		Mouse	PMID:17021013

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern