Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDE1
  • Mouse genes Nde1
  • Rat genes Nde1
  • Zfish genes nde1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nde1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	NDE1	IPI	UniProtKB:Q9NXR1	Human	PMID:22843697
Molecular Function	GO:0042802	identical protein binding	Nde1	IPI	PR:Q9CZA6	Mouse	PMID:15571978
Molecular Function	GO:0008017	microtubule binding	Nde1	IMP		Mouse	MGI:MGI:3513966|PMID:15473967
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:Q70YC5	Human	PMID:16682949
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:P49454	Human	PMID:17600710
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:Q9GZM8	Human	PMID:22843697
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:P62258	Human	PMID:25332407
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:Q9NRI5	Human	PMID:29961565
Molecular Function	GO:0005515	protein binding	NDE1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:E9Q6R7|UniProtKB:P11531	Mouse	MGI:MGI:5319752|PMID:22028625
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:O14576	Mouse	MGI:MGI:4420495|PMID:19927128
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:Q9NRI5	Mouse	MGI:MGI:6694457|PMID:29961565
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:Q155P7	Mouse	MGI:MGI:3583501|PMID:15939891
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:P43034	Mouse	MGI:MGI:4442527|PMID:20360068
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:Q155P7	Mouse	MGI:MGI:1928549|PMID:11163258
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:P43034	Mouse	MGI:MGI:1928549|PMID:11163258
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:P11983|UniProtKB:P43034|UniProtKB:P48725|UniProtKB:P63168|UniProtKB:P83887|UniProtKB:Q155P7|UniProtKB:Q60898|UniProtKB:Q7TSH4	Mouse	MGI:MGI:1928549|PMID:11163258
Molecular Function	GO:0005515	protein binding	Nde1	IPI	PR:Q06507	Mouse	PMID:18983980
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:B1AWC9	Mouse	PMID:18983980
Molecular Function	GO:0005515	protein binding	Nde1	IPI	PR:Q01063	Mouse	PMID:18983980
Molecular Function	GO:0005515	protein binding	Nde1	IPI	UniProtKB:P43033	Rat	PMID:10940388|RGD:633389
Molecular Function	GO:0019904	protein domain specific binding	Nde1	IMP		Rat	PMID:10940388|RGD:633389
Cellular Component	GO:0005813	centrosome	NDE1	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	NDE1	IDA		Human	PMID:21529752
Cellular Component	GO:0005813	centrosome	Nde1	IDA		Mouse	PMID:15473967
Cellular Component	GO:0005813	centrosome	Nde1	IDA		Mouse	PMID:11163258
Cellular Component	GO:0000776	kinetochore	NDE1	IDA		Human	PMID:17600710
Cellular Component	GO:0016020	membrane	NDE1	HDA		Human	PMID:19946888
Cellular Component	GO:0005815	microtubule organizing center	Nde1	IDA		Mouse	MGI:MGI:1928549|PMID:11163258
Cellular Component	GO:0005819	spindle	Nde1	IDA		Mouse	PMID:15473967
Cellular Component	GO:0031616	spindle pole centrosome	Nde1	IDA		Mouse	MGI:MGI:3513966|PMID:15473967
Cellular Component	GO:0045202	synapse	Nde1	IDA		Mouse	PMID:18983980
Biological Process	GO:0051298	centrosome duplication	Nde1	IMP		Mouse	MGI:MGI:3513966|PMID:15473967
Biological Process	GO:0021987	cerebral cortex development	NDE1	IMP		Human	PMID:21529752
Biological Process	GO:0021987	cerebral cortex development	Nde1	IGI	MGI:MGI:109520	Mouse	PMID:18469343
Biological Process	GO:0051303	establishment of chromosome localization	NDE1	IMP		Human	PMID:17600710
Biological Process	GO:0000132	establishment of mitotic spindle orientation	NDE1	IMP		Human	PMID:19468067
Biological Process	GO:0030900	forebrain development	Nde1	IMP	MGI:MGI:3514026	Mouse	PMID:15473967
Biological Process	GO:0007020	microtubule nucleation	Nde1	IDA		Mouse	PMID:11163258
Biological Process	GO:0031023	microtubule organizing center organization	Nde1	IMP		Mouse	MGI:MGI:1928549|PMID:11163258
Biological Process	GO:0007405	neuroblast proliferation	Nde1	IMP	MGI:MGI:3514026	Mouse	PMID:15473967
Biological Process	GO:0001764	neuron migration	Nde1	IMP		Mouse	MGI:MGI:1928549|PMID:11163258
Biological Process	GO:0032536	regulation of cell projection size	nde1	IMP	ZFIN:ZDB-MRPHLNO-110420-3	Zfish	PMID:21394081
Biological Process	GO:0047496	vesicle transport along microtubule	Nde1	IGI	MGI:MGI:1932915	Mouse	PMID:16107726
Biological Process	GO:0047496	vesicle transport along microtubule	Nde1	IGI	MGI:MGI:109520	Mouse	PMID:16107726

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern