Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDFIP1
  • Mouse genes Ndfip1
  • Rat genes Ndfip1
  • Zfish genes ndfip1,ndfip1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndfip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NDFIP1	IPI	UniProtKB:P49281	Human	PMID:18776082
Molecular Function	GO:0005515	protein binding	NDFIP1	IPI	UniProtKB:P49281-1	Human	PMID:18776082
Molecular Function	GO:0005515	protein binding	NDFIP1	IPI	UniProtKB:P49281	Human	PMID:19706893
Molecular Function	GO:0005515	protein binding	NDFIP1	IPI	UniProtKB:Q6PJG6	Human	PMID:25631046
Molecular Function	GO:0005515	protein binding	NDFIP1	IPI	UniProtKB:P07919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ndfip1	IPI	PR:Q8C863	Mouse	PMID:17137798
Molecular Function	GO:0005515	protein binding	Ndfip1	IPI	PR:P46935	Mouse	PMID:11042109
Molecular Function	GO:0005515	protein binding	Ndfip1	IPI	RGD:735047	Rat	PMID:22417925|RGD:6893327
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	UniProtKB:Q96PU5	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	UniProtKB:Q96J02	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	PR:P46935	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	UniProtKB:P46934	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	PR:Q8C863	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	UniProtKB:O00308	Mouse	PMID:11748237
Molecular Function	GO:0050699	WW domain binding	Ndfip1	IPI	UniProtKB:Q76N89	Mouse	PMID:11748237
Cellular Component	GO:0005938	cell cortex	Ndfip1	IDA		Mouse	PMID:17137798
Cellular Component	GO:0005794	Golgi apparatus	Ndfip1	IDA		Mouse	PMID:11748237
Cellular Component	GO:0048471	perinuclear region of cytoplasm	NDFIP1	IDA		Human	PMID:18776082
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0032633	interleukin-4 production	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0006879	intracellular iron ion homeostasis	NDFIP1	IMP		Human	PMID:18776082
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0010629	negative regulation of gene expression	NDFIP1	IMP		Human	PMID:18776082
Biological Process	GO:0050728	negative regulation of inflammatory response	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0032713	negative regulation of interleukin-4 production	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0048294	negative regulation of isotype switching to IgE isotypes	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0051224	negative regulation of protein transport	NDFIP1	IMP		Human	PMID:18776082
Biological Process	GO:0032410	negative regulation of transporter activity	NDFIP1	IMP		Human	PMID:18776082
Biological Process	GO:0002829	negative regulation of type 2 immune response	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	NDFIP1	HMP		Human	PMID:12761501
Biological Process	GO:0045732	positive regulation of protein catabolic process	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0045732	positive regulation of protein catabolic process	Ndfip1	IDA		Mouse	PMID:17137798
Biological Process	GO:0031398	positive regulation of protein ubiquitination	NDFIP1	IMP		Human	PMID:18776082
Biological Process	GO:0031398	positive regulation of protein ubiquitination	NDFIP1	IDA		Human	PMID:25631046
Biological Process	GO:0030163	protein catabolic process	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0030163	protein catabolic process	Ndfip1	IDA		Mouse	PMID:17137798
Biological Process	GO:0048302	regulation of isotype switching to IgG isotypes	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0045619	regulation of lymphocyte differentiation	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798
Biological Process	GO:0002761	regulation of myeloid leukocyte differentiation	Ndfip1	IMP	MGI:MGI:3695433	Mouse	PMID:17137798

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern