Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDRG1
  • Mouse genes Ndrg1
  • Rat genes Ndrg1
  • Zfish genes ndrg1a,ndrg1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndrg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	NDRG1	IDA		Human	PMID:17786215
Molecular Function	GO:0045296	cadherin binding	NDRG1	HDA		Human	PMID:25468996
Molecular Function	GO:0043015	gamma-tubulin binding	NDRG1	IDA		Human	PMID:15247272
Molecular Function	GO:0008017	microtubule binding	NDRG1	IDA		Human	PMID:15247272
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:15607035
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P12956	Human	PMID:17220478
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P27824	Human	PMID:17220478
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P35222	Human	PMID:17220478
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P02647	Human	PMID:17786215
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:P02652	Human	PMID:17786215
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q16799	Human	PMID:17786215
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9UI14	Human	PMID:17786215
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:O75446	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q3SYB3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q6PID6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q6ZNA4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q8IUW3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q8N488	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q96NC0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q99932-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9BYZ2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9H204	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9H6J7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9H816	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NDRG1	IPI	UniProtKB:Q9Y3D2	Human	PMID:32814053
Molecular Function	GO:0031267	small GTPase binding	NDRG1	IDA		Human	PMID:17786215
Cellular Component	GO:0005912	adherens junction	NDRG1	IDA		Human	PMID:12432451
Cellular Component	GO:0005813	centrosome	NDRG1	IDA		Human	PMID:15247272
Cellular Component	GO:0005737	cytoplasm	NDRG1	IDA		Human	PMID:9766676
Cellular Component	GO:0005737	cytoplasm	Ndrg1	IDA		Mouse	MGI:MGI:3041895|PMID:15082788
Cellular Component	GO:0005829	cytosol	NDRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	NDRG1	HDA		Human	PMID:19056867
Cellular Component	GO:0005874	microtubule	NDRG1	IDA		Human	PMID:15247272
Cellular Component	GO:0015630	microtubule cytoskeleton	NDRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Ndrg1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005634	nucleus	NDRG1	IDA		Human	PMID:9766676
Cellular Component	GO:0048471	perinuclear region of cytoplasm	NDRG1	IDA		Human	PMID:17786215
Cellular Component	GO:0005886	plasma membrane	NDRG1	IDA		Human	PMID:12432451
Cellular Component	GO:0055038	recycling endosome membrane	NDRG1	IDA		Human	PMID:17786215
Biological Process	GO:0071456	cellular response to hypoxia	NDRG1	IEP		Human	PMID:20810912
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	NDRG1	IEP		Human	PMID:9766676
Biological Process	GO:0045576	mast cell activation	Ndrg1	IDA		Mouse	PMID:12804568
Biological Process	GO:0008285	negative regulation of cell population proliferation	Ndrg1	IMP		Mouse	MGI:MGI:5502477|PMID:23555679
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	Ndrg1	IMP		Mouse	MGI:MGI:3041895|PMID:15082788
Biological Process	GO:0045580	regulation of T cell differentiation	ndrg1b	IGI	ZFIN:ZDB-GENE-031002-50	Zfish	PMID:27827822
Biological Process	GO:0048538	thymus development	ndrg1b	IMP	ZFIN:ZDB-MRPHLNO-170308-1	Zfish	PMID:27827822

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern