Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDST1
  • Mouse genes Ndst1
  • Rat genes Ndst1
  • Zfish genes ndst1a,ndst1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndst1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST1	IDA		Human	PMID:35137078
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST1	IMP		Human	PMID:9230113
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Mouse	MGI:MGI:6870964|PMID:10758005
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Mouse	PMID:11087757
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Mouse	PMID:18487608
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Rat	PMID:1379236|RGD:68801
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Rat	PMID:8483907|RGD:151356652
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	Ndst1	IDA		Rat	PMID:9915799|RGD:12907548
Molecular Function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	ndst1b	IDA		Zfish	PMID:19858418
Molecular Function	GO:0019213	deacetylase activity	Ndst1	IDA		Mouse	PMID:11087757
Molecular Function	GO:0102140	heparan sulfate N-deacetylase activity	NDST1	IDA		Human	PMID:35137078
Molecular Function	GO:0102140	heparan sulfate N-deacetylase activity	Ndst1	IDA		Mouse	MGI:MGI:6870964|PMID:10758005
Molecular Function	GO:0102140	heparan sulfate N-deacetylase activity	Ndst1	IDA		Mouse	MGI:MGI:6867160|PMID:12634318
Molecular Function	GO:0102140	heparan sulfate N-deacetylase activity	Ndst1	IDA		Rat	PMID:8483907|RGD:151356652
Molecular Function	GO:0102140	heparan sulfate N-deacetylase activity	Ndst1	IMP		Rat	PMID:9915799|RGD:12907548
Molecular Function	GO:0050119	N-acetylglucosamine deacetylase activity	Ndst1	IDA		Mouse	PMID:18487608
Molecular Function	GO:0050119	N-acetylglucosamine deacetylase activity	Ndst1	IDA		Mouse	PMID:11087757
Molecular Function	GO:0005515	protein binding	NDST1	IPI	UniProtKB:Q93063	Human	PMID:18337501
Molecular Function	GO:0005515	protein binding	NDST1	IPI	UniProtKB:Q16394	Human	PMID:35137078
Molecular Function	GO:0005515	protein binding	NDST1	IPI	UniProtKB:Q93063	Human	PMID:35137078
Molecular Function	GO:0005515	protein binding	Ndst1	IPI	UniProtKB:P70428	Mouse	MGI:MGI:3778322|PMID:18337501
Molecular Function	GO:0008146	sulfotransferase activity	Ndst1	IDA		Mouse	PMID:11087757
Cellular Component	GO:0005794	Golgi apparatus	Ndst1	IDA		Mouse	PMID:11687650
Cellular Component	GO:0032588	trans-Golgi network membrane	NDST1	IDA		Human	PMID:9230113
Biological Process	GO:0009887	animal organ morphogenesis	Ndst1	IMP	MGI:MGI:1888706	Mouse	PMID:10852901
Biological Process	GO:0009887	animal organ morphogenesis	Ndst1	IMP	MGI:MGI:1889939	Mouse	PMID:10664446
Biological Process	GO:0035904	aorta development	Ndst1	IMP		Mouse	PMID:25807483
Biological Process	GO:0003279	cardiac septum development	Ndst1	IMP		Mouse	PMID:25807483
Biological Process	GO:0008283	cell population proliferation	Ndst1	IMP		Mouse	PMID:26024086
Biological Process	GO:0060976	coronary vasculature development	Ndst1	IMP		Mouse	PMID:25807483
Biological Process	GO:1904888	cranial skeletal system development	ndst1a	IMP	ZFIN:ZDB-MRPHLNO-150602-2,ZFIN:ZDB-MRPHLNO-150602-3	Zfish	PMID:25767878
Biological Process	GO:1904888	cranial skeletal system development	ndst1a	IMP	ZFIN:ZDB-MRPHLNO-150602-3	Zfish	PMID:25767878
Biological Process	GO:1904888	cranial skeletal system development	ndst1a	IMP	ZFIN:ZDB-MRPHLNO-150602-2	Zfish	PMID:25767878
Biological Process	GO:0009790	embryo development	Ndst1	IGI	MGI:MGI:98297	Mouse	PMID:16020517
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0030900	forebrain development	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0030900	forebrain development	Ndst1	IGI	MGI:MGI:98297	Mouse	PMID:16020517
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0007507	heart development	Ndst1	IMP		Mouse	PMID:25807483
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ndst1	IMP	MGI:MGI:3589211	Mouse	PMID:23846497
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ndst1	IMP		Mouse	PMID:30377379
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:18385133
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ndst1	IDA		Mouse	PMID:18487608
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ndst1	IMP		Rat	PMID:9915799|RGD:12907548
Biological Process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Ndst1	IDA		Mouse	MGI:MGI:6870964|PMID:10758005
Biological Process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Ndst1	IDA		Rat	PMID:1379236|RGD:68801
Biological Process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Ndst1	IDA		Rat	PMID:8483907|RGD:151356652
Biological Process	GO:0030901	midbrain development	Ndst1	IGI	MGI:MGI:98297	Mouse	PMID:16020517
Biological Process	GO:0000271	polysaccharide biosynthetic process	Ndst1	IMP	MGI:MGI:1888706	Mouse	PMID:10852901
Biological Process	GO:0043410	positive regulation of MAPK cascade	Ndst1	IMP	MGI:MGI:3589383	Mouse	PMID:16020517
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Ndst1	IGI	MGI:MGI:98297	Mouse	PMID:16020517
Biological Process	GO:0006477	protein sulfation	Ndst1	IMP	MGI:MGI:1888706	Mouse	PMID:10852901
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Ndst1	IMP	MGI:MGI:1888706	Mouse	PMID:10852901
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Ndst1	IMP	MGI:MGI:1889939	Mouse	PMID:10664446
Biological Process	GO:0051923	sulfation	ndst1b	IMP	ZFIN:ZDB-MRPHLNO-100430-5	Zfish	PMID:19858418
Biological Process	GO:0001570	vasculogenesis	ndst1b	IMP	ZFIN:ZDB-MRPHLNO-100430-5	Zfish	PMID:19858418

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern