Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDUFC2,NDUFC2-KCTD14
  • Mouse genes Ndufc2
  • Rat genes Ndufc2
  • Zfish genes ndufc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndufc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NDUFC2	IPI	UniProtKB:Q9GZY4	Human	PMID:32320651
Molecular Function	GO:0005515	protein binding	NDUFC2	IPI	UniProtKB:Q9NWH2	Human	PMID:33753518
Cellular Component	GO:0005737	cytoplasm	NDUFC2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005743	mitochondrial inner membrane	Ndufc2	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFC2	IPI		Human	PMID:28844695
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFC2	IDA		Human	PMID:12611891
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFC2	IDA		Human	PMID:27626371
Cellular Component	GO:0005739	mitochondrion	NDUFC2-KCTD14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	NDUFC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Ndufc2	HDA		Mouse	PMID:18614015
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFC2	IMP		Human	PMID:27626371
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFC2	IMP		Human	PMID:32969598
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:0060547	negative regulation of necrotic cell death	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:2001171	positive regulation of ATP biosynthetic process	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458
Biological Process	GO:0050727	regulation of inflammatory response	Ndufc2	IMP		Rat	PMID:26888427|RGD:11040458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern