Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDUFS1
  • Mouse genes Ndufs1
  • Rat genes Ndufs1
  • Zfish genes ndufs1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndufs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0009055	electron transfer activity	Ndufs1	IMP		Mouse	MGI:MGI:6478059|PMID:27799543
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS1	IMP		Human	PMID:15824269
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS1	IMP		Human	PMID:16478720
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS1	IMP		Human	PMID:16870178
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS1	IMP		Human	PMID:30879903
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS1	IMP		Human	PMID:31557978
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs1	IMP		Mouse	MGI:MGI:6478059|PMID:27799543
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs1	IMP		Mouse	MGI:MGI:6432573|PMID:32072193
Molecular Function	GO:0005515	protein binding	NDUFS1	IPI	UniProtKB:O75251	Human	PMID:15186778
Molecular Function	GO:0005515	protein binding	NDUFS1	IPI	UniProtKB:P23804	Human	PMID:30879903
Molecular Function	GO:0005515	protein binding	NDUFS1	IPI	UniProtKB:Q00987	Human	PMID:30879903
Molecular Function	GO:0005515	protein binding	NDUFS1	IPI	UniProtKB:Q99650	Human	PMID:32807793
Molecular Function	GO:0005515	protein binding	Ndufs1	IPI	UniProtKB:O08715	Mouse	MGI:MGI:6432573|PMID:32072193
Cellular Component	GO:0005758	mitochondrial intermembrane space	NDUFS1	IDA		Human	PMID:15186778
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS1	IPI		Human	PMID:28844695
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS1	IDA		Human	PMID:12611891
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS1	IMP		Human	PMID:16478720
Cellular Component	GO:0005739	mitochondrion	NDUFS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	NDUFS1	IDA		Human	PMID:30879903
Cellular Component	GO:0005739	mitochondrion	Ndufs1	IDA		Mouse	MGI:MGI:6432573|PMID:32072193
Cellular Component	GO:0005739	mitochondrion	Ndufs1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ndufs1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043209	myelin sheath	Ndufs1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Biological Process	GO:0008637	apoptotic mitochondrial changes	NDUFS1	IDA		Human	PMID:15186778
Biological Process	GO:0046034	ATP metabolic process	NDUFS1	IMP		Human	PMID:15186778
Biological Process	GO:0045333	cellular respiration	NDUFS1	IMP		Human	PMID:15186778
Biological Process	GO:0045333	cellular respiration	NDUFS1	IMP		Human	PMID:16478720
Biological Process	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	NDUFS1	IMP		Human	PMID:31557978
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFS1	IMP		Human	PMID:30879903
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFS1	IMP		Human	PMID:31557978
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	Ndufs1	IMP		Mouse	MGI:MGI:6478059|PMID:27799543
Biological Process	GO:0072593	reactive oxygen species metabolic process	NDUFS1	IMP		Human	PMID:15186778
Biological Process	GO:0072593	reactive oxygen species metabolic process	NDUFS1	IMP		Human	PMID:16478720
Biological Process	GO:0072593	reactive oxygen species metabolic process	NDUFS1	IMP		Human	PMID:16870178
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	NDUFS1	IMP		Human	PMID:15186778
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	NDUFS1	IMP		Human	PMID:16478720

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern