Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDUFS4
  • Mouse genes Ndufs4
  • Rat genes Ndufs4
  • Zfish genes ndufs4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndufs4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS4	IMP		Human	PMID:15038602
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS4	IMP		Human	PMID:16870178
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	NDUFS4	IMP		Human	PMID:16478720
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs4	IMP	MGI:3793713	Mouse	PMID:29501746
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs4	IMP	MGI:3527173	Mouse	PMID:26712463
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs4	IMP	MGI:MGI:3793713	Mouse	PMID:18396137
Molecular Function	GO:0008137	NADH dehydrogenase (ubiquinone) activity	Ndufs4	IDA		Mouse	PMID:10747996
Molecular Function	GO:0005515	protein binding	NDUFS4	IPI	UniProtKB:P51572	Human	PMID:31206022
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS4	IPI		Human	PMID:28844695
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS4	IMP		Human	PMID:11112787
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS4	IDA		Human	PMID:12611891
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS4	IMP		Human	PMID:16478720
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFS4	IDA		Human	PMID:27626371
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	Ndufs4	IDA		Mouse	PMID:24154540
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	Ndufs4	IDA		Mouse	PMID:18396137
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	Ndufs4	IDA		Mouse	PMID:10747996
Cellular Component	GO:0005739	mitochondrion	NDUFS4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	NDUFS4	IDA		Human	PMID:31206022
Cellular Component	GO:0005739	mitochondrion	Ndufs4	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ndufs4	IDA		Mouse	PMID:18396137
Cellular Component	GO:0005739	mitochondrion	Ndufs4	HDA		Mouse	PMID:18614015
Biological Process	GO:0030534	adult behavior	Ndufs4	IMP	MGI:3527173	Mouse	PMID:28327638
Biological Process	GO:0007628	adult walking behavior	Ndufs4	IMP	MGI:3793713	Mouse	PMID:26363424
Biological Process	GO:0007420	brain development	NDUFS4	IMP		Human	PMID:14765537
Biological Process	GO:0007420	brain development	Ndufs4	IMP	MGI:3793713	Mouse	PMID:28916769
Biological Process	GO:0045333	cellular respiration	NDUFS4	IMP		Human	PMID:16478720
Biological Process	GO:0071453	cellular response to oxygen levels	Ndufs4	IMP	MGI:3527173	Mouse	PMID:26437605
Biological Process	GO:0050890	cognition	Ndufs4	IMP	MGI:3527173	Mouse	PMID:28327638
Biological Process	GO:0042417	dopamine metabolic process	Ndufs4	IMP	MGI:3527173	Mouse	PMID:28327638
Biological Process	GO:0006954	inflammatory response	Ndufs4	IMP	MGI:3793713	Mouse	PMID:25652399
Biological Process	GO:0045087	innate immune response	Ndufs4	IMP	MGI:3793713	Mouse	PMID:25652399
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFS4	IMP		Human	PMID:11112787
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	NDUFS4	IMP		Human	PMID:15038602
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	Ndufs4	IMP	MGI:MGI:3793713	Mouse	PMID:18396137
Biological Process	GO:0051402	neuron apoptotic process	Ndufs4	IMP	MGI:3793713	Mouse	PMID:25652399
Biological Process	GO:0048666	neuron development	Ndufs4	IMP	MGI:3793713	Mouse	PMID:26363424
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	NDUFS4	IMP		Human	PMID:16478720
Biological Process	GO:0036343	psychomotor behavior	Ndufs4	IMP	MGI:3527173	Mouse	PMID:28327638
Biological Process	GO:0072593	reactive oxygen species metabolic process	NDUFS4	IMP		Human	PMID:16870178
Biological Process	GO:0072593	reactive oxygen species metabolic process	Ndufs4	IMP	MGI:3793713	Mouse	PMID:29501746
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Ndufs4	IMP	MGI:3527173	Mouse	PMID:26712463
Biological Process	GO:0001932	regulation of protein phosphorylation	NDUFS4	IMP		Human	PMID:11165261
Biological Process	GO:0022904	respiratory electron transport chain	Ndufs4	IMP	MGI:3793713	Mouse	PMID:30391276
Biological Process	GO:0003016	respiratory system process	Ndufs4	IMP	MGI:3527173	Mouse	PMID:28327638
Biological Process	GO:0051591	response to cAMP	NDUFS4	IMP		Human	PMID:11165261
Biological Process	GO:0051591	response to cAMP	NDUFS4	IMP		Human	PMID:11181577
Biological Process	GO:0014876	response to injury involved in regulation of muscle adaptation	Ndufs4	IMP	MGI:3793713	Mouse	PMID:29501746
Biological Process	GO:0007605	sensory perception of sound	Ndufs4	IMP	MGI:MGI:3793713	Mouse	PMID:18396137
Biological Process	GO:0007601	visual perception	Ndufs4	IMP	MGI:3793713	Mouse	PMID:25652399

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern