Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NECTIN1
  • Mouse genes Nectin1
  • Rat genes Nectin1
  • Zfish genes nectin1a,nectin1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nectin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	Nectin1	IDA		Rat	PMID:18181141|RGD:2314668
Molecular Function	GO:0050839	cell adhesion molecule binding	NECTIN1	IPI	UniProtKB:Q9NQS3	Human	PMID:12438620
Molecular Function	GO:0042802	identical protein binding	NECTIN1	IPI	UniProtKB:Q15223	Human	PMID:21982860
Molecular Function	GO:0042802	identical protein binding	NECTIN1	IPI	UniProtKB:Q15223	Human	PMID:22902367
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:G3G922	Human	PMID:11277703
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q69091	Human	PMID:11277703
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q96NY8	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q9NQS3	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q96NY8	Human	PMID:22902367
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q9NQS3-1	Human	PMID:22902367
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:O00560	Human	PMID:26787460
Molecular Function	GO:0005515	protein binding	NECTIN1	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nectin1	IPI	UniProtKB:Q9JLB9	Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0005515	protein binding	Nectin1	IPI	PR:Q8C0V9	Mouse	PMID:22512338
Molecular Function	GO:0005515	protein binding	Nectin1	IPI	RGD:708561	Rat	PMID:18181141|RGD:2314668
Molecular Function	GO:0042803	protein homodimerization activity	Nectin1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0044877	protein-containing complex binding	Nectin1	IMP		Rat	PMID:15328010|RGD:1599806
Molecular Function	GO:0038023	signaling receptor activity	Nectin1	IDA		Mouse	PMID:11090177
Molecular Function	GO:0046790	virion binding	Nectin1	IMP		Rat	PMID:12584355|RGD:1599797
Cellular Component	GO:0005912	adherens junction	NECTIN1	IDA		Human	PMID:10225955
Cellular Component	GO:0005912	adherens junction	Nectin1	IDA		Mouse	PMID:15328010
Cellular Component	GO:0005912	adherens junction	Nectin1	IDA		Mouse	PMID:12515806
Cellular Component	GO:0005912	adherens junction	Nectin1	IDA		Mouse	PMID:15728677
Cellular Component	GO:0043296	apical junction complex	Nectin1	IDA		Mouse	PMID:22512338
Cellular Component	GO:0030424	axon	Nectin1	IDA		Rat	PMID:16801389|RGD:1599798
Cellular Component	GO:0044291	cell-cell contact zone	Nectin1	IDA		Mouse	PMID:23533177
Cellular Component	GO:0030425	dendrite	Nectin1	IDA		Rat	PMID:16801389|RGD:1599798
Cellular Component	GO:0032584	growth cone membrane	Nectin1	IDA		Rat	PMID:18181141|RGD:2314668
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Nectin1	IDA		Mouse	PMID:11827984
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Nectin1	IEP		Mouse	PMID:11827984
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Nectin1	IDA		Rat	PMID:11827984|RGD:1599809
Cellular Component	GO:0043005	neuron projection	Nectin1	IDA		Rat	PMID:11827984|RGD:1599809
Cellular Component	GO:0005886	plasma membrane	Nectin1	IDA		Rat	PMID:18181141|RGD:2314668
Cellular Component	GO:0048787	presynaptic active zone membrane	Nectin1	IDA		Mouse	PMID:11827984
Cellular Component	GO:0048787	presynaptic active zone membrane	Nectin1	IEP		Mouse	PMID:11827984
Cellular Component	GO:0045202	synapse	Nectin1	IDA		Rat	PMID:16801389|RGD:1599798
Biological Process	GO:0007411	axon guidance	Nectin1	IMP		Rat	PMID:15328010|RGD:1599806
Biological Process	GO:0048593	camera-type eye morphogenesis	Nectin1	IMP	MGI:MGI:3605480	Mouse	PMID:15728677
Biological Process	GO:0098609	cell-cell adhesion	Nectin1	IMP	MGI:MGI:3814719	Mouse	PMID:18703497
Biological Process	GO:0002934	desmosome organization	Nectin1	IMP	MGI:MGI:3814719	Mouse	PMID:18703497
Biological Process	GO:0070166	enamel mineralization	Nectin1	IMP	MGI:MGI:3814719	Mouse	PMID:18703497
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Nectin1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	Nectin1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Biological Process	GO:0006826	iron ion transport	Nectin1	IMP	MGI:MGI:3814719	Mouse	PMID:18703497
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	Nectin1	IMP	MGI:MGI:3605480	Mouse	PMID:15728677
Biological Process	GO:1903929	primary palate development	nectin1a	IMP	ZFIN:ZDB-GENO-211028-9	Zfish	PMID:33436952
Biological Process	GO:1902414	protein localization to cell junction	Nectin1	IDA		Mouse	PMID:22512338
Biological Process	GO:0051963	regulation of synapse assembly	Nectin1	IMP		Rat	PMID:11827984|RGD:1599809
Biological Process	GO:0050807	regulation of synapse organization	Nectin1	EXP		Rat	PMID:11827984|RGD:1599809
Biological Process	GO:0050807	regulation of synapse organization	Nectin1	IDA		Rat	PMID:11827984|RGD:1599809
Biological Process	GO:0060041	retina development in camera-type eye	Nectin1	IMP	MGI:MGI:3605480	Mouse	PMID:15728677
Biological Process	GO:0046718	viral entry into host cell	Nectin1	IMP		Rat	PMID:12584355|RGD:1599797

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern