Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NECTIN3
  • Mouse genes Nectin3
  • Rat genes Nectin3
  • Zfish genes nectin3a,nectin3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nectin3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	NECTIN3	IPI	UniProtKB:Q15223	Human	PMID:12438620
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q495A1	Human	PMID:19011627
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q15223	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q495A1	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q92692	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q92692	Human	PMID:23758976
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:O76081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q9BYR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NECTIN3	IPI	UniProtKB:P21333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nectin3	IPI	UniProtKB:Q9JKF6	Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0042803	protein homodimerization activity	Nectin3	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Cellular Component	GO:0005912	adherens junction	Nectin3	IDA		Mouse	PMID:15328010
Cellular Component	GO:0005912	adherens junction	Nectin3	IDA		Mouse	PMID:12515806
Cellular Component	GO:0005912	adherens junction	Nectin3	IDA		Mouse	PMID:10744716
Cellular Component	GO:0005912	adherens junction	Nectin3	IDA		Mouse	PMID:15728677
Cellular Component	GO:0043296	apical junction complex	Nectin3	IDA		Mouse	PMID:16249236
Cellular Component	GO:0043296	apical junction complex	Nectin3	IDA		Mouse	PMID:22512338
Cellular Component	GO:0030424	axon	Nectin3	IDA		Rat	PMID:16801389|RGD:1599798
Cellular Component	GO:0044291	cell-cell contact zone	Nectin3	IDA		Mouse	PMID:23533177
Cellular Component	GO:0005911	cell-cell junction	Nectin3	IDA		Mouse	MGI:MGI:5532791|PMID:23990464
Cellular Component	GO:0005911	cell-cell junction	Nectin3	IDA		Mouse	PMID:15660130
Cellular Component	GO:0005911	cell-cell junction	Nectin3	IDA		Mouse	PMID:12759359
Cellular Component	GO:0030425	dendrite	Nectin3	IDA		Rat	PMID:16801389|RGD:1599798
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Nectin3	IDA		Mouse	PMID:11827984
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Nectin3	IEP		Mouse	PMID:11827984
Cellular Component	GO:0005886	plasma membrane	Nectin3	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Cellular Component	GO:0098839	postsynaptic density membrane	Nectin3	IEP		Mouse	PMID:11827984
Cellular Component	GO:0098839	postsynaptic density membrane	Nectin3	IDA		Mouse	PMID:11827984
Cellular Component	GO:0045202	synapse	Nectin3	IDA		Rat	PMID:16801389|RGD:1599798
Biological Process	GO:0007155	cell adhesion	Nectin3	IDA		Mouse	PMID:10744716
Biological Process	GO:0098609	cell-cell adhesion	Nectin3	IDA		Mouse	PMID:12740392
Biological Process	GO:0098609	cell-cell adhesion	Nectin3	IDA		Mouse	PMID:12759359
Biological Process	GO:0061951	establishment of protein localization to plasma membrane	Nectin3	IMP		Mouse	MGI:MGI:5532791|PMID:23990464
Biological Process	GO:0009566	fertilization	Nectin3	IMP	MGI:MGI:3605481	Mouse	PMID:15728677
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	Nectin3	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	Nectin3	IMP	MGI:MGI:3605481	Mouse	PMID:15728677
Biological Process	GO:1902414	protein localization to cell junction	Nectin3	IMP		Mouse	PMID:22512338
Biological Process	GO:1902414	protein localization to cell junction	Nectin3	IDA		Mouse	PMID:22512338
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Nectin3	IMP	MGI:MGI:3605481	Mouse	PMID:15728677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern