Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEDD8
  • Mouse genes Nedd8
  • Rat genes Nedd8
  • Zfish genes nedd8,nedd8l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nedd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q9U3C8	Human	PMID:15988528
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P09936	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:17318178
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q9Y297	Human	PMID:17318178
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:18264111
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:18264111
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P18124	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P23396	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P60866	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P62081	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P62913	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:18723677
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:18805092
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:19713960
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P62913	Human	PMID:19713960
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:19713960
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q8WXE9	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P07437	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P23396	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P60866	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P62913	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q6P9F5	Human	PMID:21474709
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:21765416
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:21765416
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:O94888	Human	PMID:22466964
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q9BTE7	Human	PMID:24192928
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:24949976
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:O15037	Human	PMID:30659753
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P54725	Human	PMID:30659753
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q9UNA4	Human	PMID:30659753
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:Q13616	Human	PMID:32726803
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P04271	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P07437	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P09936	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEDD8	IPI	UniProtKB:P63151	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nedd8	IPI	UniProtKB:A0A0F6B423	Mouse	MGI:MGI:6094823|PMID:27822540
Molecular Function	GO:0005515	protein binding	Nedd8	IPI	PR:P30561	Mouse	PMID:12215427
Molecular Function	GO:0031625	ubiquitin protein ligase binding	NEDD8	IPI	UniProtKB:P61081	Human	PMID:15694336
Cellular Component	GO:0005829	cytosol	NEDD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	NEDD8	HDA		Human	PMID:20458337
Cellular Component	GO:0005654	nucleoplasm	NEDD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nedd8	IDA		Mouse	PMID:12215427
Cellular Component	GO:0005634	nucleus	Nedd8	IDA		Rat	PMID:14557245|RGD:2302388
Biological Process	GO:0051607	defense response to virus	nedd8	IMP	ZFIN:ZDB-GENO-200213-5	Zfish	PMID:31293590
Biological Process	GO:0008104	protein localization	Nedd8	IDA		Mouse	PMID:12215427
Biological Process	GO:0045116	protein neddylation	NEDD8	IDA		Human	PMID:10500095
Biological Process	GO:0045116	protein neddylation	Nedd8	IDA		Rat	PMID:17950367|RGD:2301431
Biological Process	GO:0045116	protein neddylation	nedd8	IMP	ZFIN:ZDB-GENO-220222-8	Zfish	PMID:32978241
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Nedd8	IDA		Mouse	PMID:12215427
Biological Process	GO:0014070	response to organic cyclic compound	Nedd8	IDA		Rat	PMID:14557245|RGD:2302388

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern