Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEK10
  • Mouse genes Nek10
  • Rat genes Nek10
  • Zfish genes nek10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nek10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004672	protein kinase activity	NEK10	IDA		Human	PMID:20956560
Cellular Component	GO:1902911	protein kinase complex	NEK10	IDA		Human	PMID:20956560
Biological Process	GO:0120197	mucociliary clearance	NEK10	IMP		Human	PMID:31959991
Biological Process	GO:0043406	positive regulation of MAP kinase activity	NEK10	IMP		Human	PMID:20956560
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	NEK10	IDA		Human	PMID:20956560
Biological Process	GO:0006468	protein phosphorylation	NEK10	IDA		Human	PMID:20956560
Biological Process	GO:1902749	regulation of cell cycle G2/M phase transition	NEK10	IMP		Human	PMID:20956560
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	NEK10	IMP		Human	PMID:20956560

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern