Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nek7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NEK7
- Mouse genes Nek7
- Rat genes Nek7
- Zfish genes nek7
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nek7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140677	molecular function activator activity	NEK7	IDA		Human	PMID:31189953
Molecular Function	GO:0140677	molecular function activator activity	NEK7	IDA		Human	PMID:36442502
Molecular Function	GO:0140677	molecular function activator activity	Nek7	IDA		Mouse	MGI:MGI:5707980\|PMID:26553871
Molecular Function	GO:0140677	molecular function activator activity	Nek7	IDA		Mouse	MGI:MGI:5751332\|PMID:26814970
Molecular Function	GO:0140677	molecular function activator activity	Nek7	IDA		Mouse	MGI:MGI:5698271\|PMID:26642356
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q6ZW76	Human	PMID:26188091
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96P20	Human	PMID:26814970
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P00558	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P42166	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:A0JP07	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:A2RUH7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:F6Y2X3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O00214-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O14829	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O75175	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O75317	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O75874	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:O94983-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P07437	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P09382	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P09471	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P14060	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P16422	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P26715	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P36382	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P43356	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P43686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P48775	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P49184	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P49746	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P50749	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P52756	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P61224	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:P79483	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q02978	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q10981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q13200	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q13428-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q13636	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q3SY56	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q68CL5-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q6P4D5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q6P5S2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q6UXH1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q7Z434	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q7Z698	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q7Z6Z7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q7Z780	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8IY82	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8N1W1-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8N2W9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8N323	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8NBT0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8NCF5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8NCR3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8TAB5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q8TB02	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96E17	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96EF9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96EY8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96GK7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96I25	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96JJ7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96L03	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96P20	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q96QH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q99944	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9BQ29	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9BT49	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9H2S6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9HC98-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9NPC7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9NVM1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9NX07	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9ULR0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9ULW0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9Y3Y4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NEK7	IPI	UniProtKB:Q9Y617	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nek7	IPI	UniProtKB:Q8R4B8	Mouse	MGI:MGI:5698271\|PMID:26642356
Molecular Function	GO:0005515	protein binding	Nek7	IPI	UniProtKB:Q8R4B8\|UniProtKB:Q96P20	Mouse	MGI:MGI:5751332\|PMID:26814970
Molecular Function	GO:0005515	protein binding	Nek7	IPI	UniProtKB:Q9CZK6	Mouse	MGI:MGI:6355663\|PMID:26188091
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NEK7	IDA		Human	PMID:19941817
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NEK7	IDA		Human	PMID:26522158
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Nek7	IDA		Rat	PMID:11516946\|RGD:8554184
Cellular Component	GO:0005737	cytoplasm	Nek7	IDA		Mouse	MGI:MGI:6355663\|PMID:26188091
Cellular Component	GO:0005815	microtubule organizing center	NEK7	IDA		Human	PMID:17586473
Cellular Component	GO:0005654	nucleoplasm	NEK7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nek7	IDA		Mouse	MGI:MGI:6355663\|PMID:26188091
Biological Process	GO:0035865	cellular response to potassium ion	Nek7	IDA		Mouse	MGI:MGI:5751332\|PMID:26814970
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	NEK7	IDA		Human	PMID:31189953
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	NEK7	IDA		Human	PMID:36442502
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	Nek7	IMP		Mouse	MGI:MGI:5751332\|PMID:26814970
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	Nek7	IDA		Mouse	MGI:MGI:5698271\|PMID:26642356
Biological Process	GO:0051973	positive regulation of telomerase activity	NEK7	IMP		Human	PMID:21531765
Biological Process	GO:1904355	positive regulation of telomere capping	NEK7	IMP		Human	PMID:21531765
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	NEK7	IMP		Human	PMID:21531765
Biological Process	GO:0006468	protein phosphorylation	NEK7	IDA		Human	PMID:12840024
Biological Process	GO:0006468	protein phosphorylation	NEK7	IDA		Human	PMID:31409757
Biological Process	GO:0007346	regulation of mitotic cell cycle	NEK7	IDA		Human	PMID:19941817

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.