Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NELFE
  • Mouse genes Nelfe
  • Rat genes Nelfe
  • Zfish genes nelfe
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nelfe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	NELFE	IDA		Human	PMID:14701750
Molecular Function	GO:0003682	chromatin binding	NELFE	IDA		Human	PMID:27256882
Molecular Function	GO:0003682	chromatin binding	Nelfe	IDA		Mouse	PMID:31399344
Molecular Function	GO:0003682	chromatin binding	Nelfe	IDA		Rat	PMID:20097260|RGD:9588536
Molecular Function	GO:0003682	chromatin binding	Nelfe	IMP		Rat	PMID:21623364|RGD:9693718
Molecular Function	GO:0003729	mRNA binding	NELFE	IDA		Human	PMID:27256882
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:12612062
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFE	IPI	UniProtKB:Q8WX92-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nelfe	IPI	UniProtKB:P11499	Mouse	MGI:MGI:5437389|PMID:22579285
Molecular Function	GO:0005515	protein binding	Nelfe	IPI	UniProtKB:Q8C4Y3	Mouse	MGI:MGI:6250769|PMID:26010750
Molecular Function	GO:0003723	RNA binding	NELFE	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	NELFE	IDA		Human	PMID:27256882
Molecular Function	GO:0003723	RNA binding	NELFE	IDA		Human	PMID:30135580
Cellular Component	GO:0000785	chromatin	NELFE	IDA		Human	PMID:14701750
Cellular Component	GO:0000785	chromatin	NELFE	IDA		Human	PMID:27256882
Cellular Component	GO:0000785	chromatin	Nelfe	IDA		Mouse	PMID:31399344
Cellular Component	GO:0032021	NELF complex	NELFE	IPI		Human	PMID:12612062
Cellular Component	GO:0032021	NELF complex	NELFE	IDA		Human	PMID:12612062
Cellular Component	GO:0016604	nuclear body	NELFE	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NELFE	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NELFE	IDA		Human	PMID:27256882
Cellular Component	GO:0005634	nucleus	NELFE	IDA		Human	PMID:12612062
Cellular Component	GO:0005634	nucleus	Nelfe	IDA		Rat	PMID:20097260|RGD:9588536
Cellular Component	GO:0005886	plasma membrane	NELFE	IDA		Human	GO_REF:0000052
Biological Process	GO:0051179	localization	NELFE	IDA		Human	PMID:30135580
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nelfe	IMP		Rat	PMID:20097260|RGD:9588536
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	NELFE	IDA		Human	PMID:12612062
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	NELFE	IDA		Human	PMID:14701750
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	NELFE	IDA		Human	PMID:27256882
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfe	IDA		Mouse	PMID:31399344
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfe	IMP		Mouse	PMID:21670248
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Nelfe	IMP		Rat	PMID:19014935|RGD:9693721
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	nelfe	IMP	ZFIN:ZDB-MRPHLNO-170117-4	Zfish	PMID:27520065
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	nelfe	IMP	ZFIN:ZDB-MRPHLNO-170117-4	Zfish	PMID:27520065
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	Nelfe	IMP		Rat	PMID:21623364|RGD:9693718
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nelfe	IMP		Rat	PMID:21623364|RGD:9693718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern