Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEO1
  • Mouse genes Neo1
  • Rat genes Neo1
  • Zfish genes neo1a,neo1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070700	BMP receptor binding	Neo1	IPI	UniProtKB:Q6ZVN8	Mouse	MGI:MGI:5644024|PMID:18326817
Molecular Function	GO:0045296	cadherin binding	Neo1	IDA		Mouse	PMID:15520228
Molecular Function	GO:0039706	co-receptor binding	NEO1	IPI	UniProtKB:Q6ZVN8	Human	PMID:18335997
Molecular Function	GO:0005515	protein binding	NEO1	IPI	UniProtKB:Q6ZVN8	Human	PMID:18335997
Molecular Function	GO:0005515	protein binding	NEO1	IPI	UniProtKB:Q9C026	Human	PMID:22084112
Molecular Function	GO:0005515	protein binding	Neo1	IPI	UniProtKB:F8VQB6	Mouse	MGI:MGI:4839446|PMID:17237772
Molecular Function	GO:0005515	protein binding	Neo1	IPI	UniProtKB:Q6NW40	Mouse	MGI:MGI:5915531|PMID:25938661
Molecular Function	GO:0005515	protein binding	Neo1	IPI	PR:Q32MD9	Mouse	PMID:15520228
Molecular Function	GO:0005515	protein binding	Neo1	IPI	UniProtKB:Q9HD67	Mouse	PMID:26651291
Molecular Function	GO:0038023	signaling receptor activity	Neo1	IPI	PR:Q52KR2	Mouse	PMID:26651291
Molecular Function	GO:0038023	signaling receptor activity	Neo1	IPI	PR:Q6PCX7	Mouse	PMID:26651291
Molecular Function	GO:0038023	signaling receptor activity	Neo1	IPI	UniProtKB:Q9R1A3	Mouse	PMID:15520228
Cellular Component	GO:0009986	cell surface	Neo1	IDA		Mouse	PMID:26651291
Cellular Component	GO:0005794	Golgi apparatus	NEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030426	growth cone	Neo1	IDA		Mouse	PMID:26651291
Cellular Component	GO:0097708	intracellular vesicle	Neo1	IDA		Mouse	PMID:26651291
Cellular Component	GO:0016020	membrane	Neo1	IDA		Mouse	PMID:26651291
Cellular Component	GO:0043025	neuronal cell body	Neo1	IDA		Rat	PMID:20457227|RGD:9850136
Cellular Component	GO:0005654	nucleoplasm	NEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NEO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098797	plasma membrane protein complex	NEO1	IDA		Human	PMID:18335997
Biological Process	GO:0000902	cell morphogenesis	neo1a	IMP	ZFIN:ZDB-MRPHLNO-200318-1	Zfish	PMID:31399534
Biological Process	GO:0000902	cell morphogenesis	neo1a	IMP	ZFIN:ZDB-MRPHLNO-110301-10	Zfish	PMID:31399534
Biological Process	GO:0006879	intracellular iron ion homeostasis	Neo1	IMP	MGI:MGI:3665445	Mouse	PMID:20065295
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	NEO1	IGI	UniProtKB:Q6ZVN8	Human	PMID:16075058
Biological Process	GO:0007520	myoblast fusion	Neo1	IMP		Mouse	PMID:15520228
Biological Process	GO:0048681	negative regulation of axon regeneration	Neo1	IMP		Mouse	PMID:26651291
Biological Process	GO:1901215	negative regulation of neuron death	Neo1	IMP		Rat	PMID:20457227|RGD:9850136
Biological Process	GO:0050709	negative regulation of protein secretion	Neo1	IDA		Mouse	PMID:20065295
Biological Process	GO:0007399	nervous system development	neo1a	IMP		Zfish	PMID:15081375
Biological Process	GO:0001841	neural tube formation	neo1a	IMP		Zfish	PMID:15081375
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Neo1	IGI	MGI:MGI:88177	Mouse	PMID:20065295
Biological Process	GO:0009306	protein secretion	Neo1	IDA		Mouse	PMID:20065295
Biological Process	GO:0048679	regulation of axon regeneration	Neo1	IGI	MGI:MGI:2443718	Mouse	PMID:26651291
Biological Process	GO:0006355	regulation of DNA-templated transcription	Neo1	IDA		Mouse	PMID:15520228
Biological Process	GO:0001756	somitogenesis	neo1a	IMP		Zfish	PMID:15081375

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern