Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NES
  • Mouse genes Nes
  • Rat genes Nes
  • Zfish genes nes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nes

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031730	CCR5 chemokine receptor binding	Nes	IPI	RGD:620596	Rat	PMID:19559698|RGD:4889986
Molecular Function	GO:0005515	protein binding	NES	IPI	UniProtKB:P08670	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NES	IPI	UniProtKB:P08670	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NES	IPI	UniProtKB:P08670	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	Nes	IPI	PR:P48432	Mouse	PMID:23447615
Cellular Component	GO:0005737	cytoplasm	NES	IDA		Human	PMID:19384922
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:14706696
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:18614158
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:23447615
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:19409199
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:19036983
Cellular Component	GO:0005737	cytoplasm	Nes	IDA		Mouse	PMID:17901127
Cellular Component	GO:0005882	intermediate filament	Nes	IDA		Mouse	PMID:9364068
Cellular Component	GO:0005882	intermediate filament	Nes	IDA		Rat	PMID:12832492|RGD:632375
Cellular Component	GO:0045111	intermediate filament cytoskeleton	NES	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	nes	IMP		Zfish	PMID:20174467|ZFIN:ZDB-PUB-100223-59
Biological Process	GO:0007420	brain development	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-15	Zfish	PMID:20174467
Biological Process	GO:0007420	brain development	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-16	Zfish	PMID:20174467
Biological Process	GO:0048858	cell projection morphogenesis	Nes	IMP		Mouse	PMID:16571784
Biological Process	GO:0021545	cranial nerve development	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-15	Zfish	PMID:20174467
Biological Process	GO:0031076	embryonic camera-type eye development	nes	IMP		Zfish	PMID:20174467|ZFIN:ZDB-PUB-100223-59
Biological Process	GO:0031076	embryonic camera-type eye development	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-16	Zfish	PMID:20174467
Biological Process	GO:0031076	embryonic camera-type eye development	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-15	Zfish	PMID:20174467
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	NES	IDA		Human	PMID:19384922
Biological Process	GO:0043066	negative regulation of apoptotic process	nes	IMP		Zfish	PMID:20174467|ZFIN:ZDB-PUB-100223-59
Biological Process	GO:0043066	negative regulation of apoptotic process	nes	IMP	ZFIN:ZDB-MRPHLNO-100423-15	Zfish	PMID:20174467
Biological Process	GO:0043086	negative regulation of catalytic activity	NES	IDA		Human	PMID:21185309
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Nes	IMP	MGI:MGI:3844224	Mouse	PMID:20963821
Biological Process	GO:0032091	negative regulation of protein binding	NES	IDA		Human	PMID:21185309
Biological Process	GO:0007399	nervous system development	Nes	IDA		Mouse	PMID:12687705
Biological Process	GO:0051402	neuron apoptotic process	Nes	IMP	MGI:MGI:3844224	Mouse	PMID:20963821
Biological Process	GO:0030844	positive regulation of intermediate filament depolymerization	Nes	IDA		Rat	PMID:12686602|RGD:633505
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Nes	IMP		Rat	PMID:20510364|RGD:8554576
Biological Process	GO:0010212	response to ionizing radiation	Nes	IEP		Rat	PMID:12445635|RGD:1642076
Biological Process	GO:0031667	response to nutrient levels	Nes	IEP		Rat	PMID:17065391|RGD:1642068
Biological Process	GO:0009410	response to xenobiotic stimulus	Nes	IEP		Rat	PMID:17510525|RGD:1642075
Biological Process	GO:0072089	stem cell proliferation	NES	IMP		Human	PMID:19384922

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern