Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEURL1
  • Mouse genes Neurl1a
  • Rat genes Neurl1
  • Zfish genes neurl1aa,neurl1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neurl1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Neurl1a	IPI	UniProtKB:Q61483	Mouse	MGI:MGI:3696936|PMID:17003037
Molecular Function	GO:0005515	protein binding	Neurl1a	IPI	UniProtKB:Q61483|UniProtKB:Q9JI71	Mouse	MGI:MGI:5700298|PMID:19723503
Molecular Function	GO:0005515	protein binding	Neurl1a	IPI	UniProtKB:Q7TN99	Mouse	MGI:MGI:5300629|PMID:22153079
Molecular Function	GO:0005515	protein binding	Neurl1a	IPI	PR:P62878	Mouse	PMID:14960280
Molecular Function	GO:0045183	translation factor activity, non-nucleic acid binding	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Neurl1a	IDA		Mouse	PMID:22153079
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Cellular Component	GO:0097440	apical dendrite	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Cellular Component	GO:0005737	cytoplasm	Neurl1a	IDA		Mouse	PMID:11997106
Cellular Component	GO:0005737	cytoplasm	Neurl1a	IDA		Mouse	PMID:11481456
Cellular Component	GO:0043197	dendritic spine	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Cellular Component	GO:0043204	perikaryon	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Cellular Component	GO:0005886	plasma membrane	NEURL1	IDA		Human	PMID:20847082
Cellular Component	GO:0005886	plasma membrane	Neurl1a	IDA		Mouse	PMID:11997106
Cellular Component	GO:0014069	postsynaptic density	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0007420	brain development	Neurl1	IEP		Rat	PMID:12213446|RGD:2302390
Biological Process	GO:0071230	cellular response to amino acid stimulus	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0030317	flagellated sperm motility	Neurl1a	IMP	MGI:MGI:2153143	Mouse	PMID:11585928
Biological Process	GO:0007595	lactation	Neurl1a	IMP	MGI:MGI:2153143	Mouse	PMID:11585928
Biological Process	GO:0008285	negative regulation of cell population proliferation	NEURL1	IDA		Human	PMID:20847082
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	NEURL1	IDA		Human	PMID:20847082
Biological Process	GO:0043065	positive regulation of apoptotic process	NEURL1	IDA		Human	PMID:20847082
Biological Process	GO:0060999	positive regulation of dendritic spine development	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	Neurl1a	IMP	MGI:MGI:2152037	Mouse	PMID:11481456
Biological Process	GO:0051491	positive regulation of filopodium assembly	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0048170	positive regulation of long-term neuronal synaptic plasticity	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0090129	positive regulation of synapse maturation	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0006513	protein monoubiquitination	Neurl1a	IDA		Mouse	MGI:MGI:5300629|PMID:22153079
Biological Process	GO:0007519	skeletal muscle tissue development	Neurl1	IEP		Rat	PMID:12213446|RGD:2302390
Biological Process	GO:0007288	sperm axoneme assembly	Neurl1a	IMP	MGI:MGI:2153143	Mouse	PMID:11585928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern