Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEUROD2
  • Mouse genes Neurod2
  • Rat genes Neurod2
  • Zfish genes neurod2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neurod2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Neurod2	IDA		Mouse	PMID:16203979
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Neurod2	IDA		Mouse	MGI:MGI:1332969|PMID:10098882
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Neurod2	IDA		Mouse	MGI:MGI:4830798|PMID:20346398
Molecular Function	GO:0070888	E-box binding	Neurod2	IDA		Mouse	MGI:MGI:2686763|PMID:14697366
Molecular Function	GO:0070888	E-box binding	Neurod2	IDA		Mouse	MGI:MGI:3789797|PMID:18214987
Molecular Function	GO:0005515	protein binding	Neurod2	IPI	UniProtKB:Q9JJ66	Mouse	MGI:MGI:5009363|PMID:19900895
Molecular Function	GO:0005515	protein binding	Neurod2	IPI	PR:P15806	Mouse	PMID:18214987
Molecular Function	GO:0005515	protein binding	Neurod2	IPI	PR:Q61286	Mouse	PMID:18214987
Molecular Function	GO:0005515	protein binding	Neurod2	IPI	PR:Q60722	Mouse	PMID:18214987
Molecular Function	GO:0046982	protein heterodimerization activity	Neurod2	IDA		Mouse	MGI:MGI:3789797|PMID:18214987
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Neurod2	IDA		Mouse	MGI:MGI:1332969|PMID:10098882
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NEUROD2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Neurod2	IDA		Mouse	MGI:MGI:4830798|PMID:20346398
Cellular Component	GO:0005634	nucleus	Neurod2	IDA		Mouse	MGI:MGI:5009405|PMID:16730830
Cellular Component	GO:0005634	nucleus	Neurod2	IDA		Mouse	MGI:MGI:5009203|PMID:10648228
Biological Process	GO:0008306	associative learning	Neurod2	IMP	MGI:MGI:2385828	Mouse	PMID:16203979
Biological Process	GO:0001662	behavioral fear response	Neurod2	IMP	MGI:MGI:2385828	Mouse	PMID:16203979
Biological Process	GO:0071277	cellular response to calcium ion	Neurod2	IDA		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:0071257	cellular response to electrical stimulus	Neurod2	IDA		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:0021695	cerebellar cortex development	Neurod2	IMP		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:2000297	negative regulation of synapse maturation	Neurod2	IDA		Mouse	MGI:MGI:5009363|PMID:19900895
Biological Process	GO:0048666	neuron development	Neurod2	IMP	MGI:MGI:2385828	Mouse	PMID:16203979
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	Neurod2	IDA		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Neurod2	IDA		Mouse	MGI:MGI:2686763|PMID:14697366
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Neurod2	IDA		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurod2	IDA		Mouse	MGI:MGI:5009203|PMID:10648228
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurod2	IDA		Mouse	MGI:MGI:3789797|PMID:18214987
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurod2	IDA		Mouse	MGI:MGI:4830798|PMID:20346398
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurod2	IDA		Mouse	MGI:MGI:5009405|PMID:16730830
Biological Process	GO:0090129	positive regulation of synapse maturation	Neurod2	IMP		Mouse	MGI:MGI:3621523|PMID:16504944
Biological Process	GO:0031915	positive regulation of synaptic plasticity	Neurod2	IDA		Mouse	MGI:MGI:5009363|PMID:19900895
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurod2	IDA		Mouse	MGI:MGI:1332969|PMID:10098882
Biological Process	GO:0016567	protein ubiquitination	Neurod2	IDA		Mouse	MGI:MGI:5009363|PMID:19900895

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern