Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFE2L3
  • Mouse genes Nfe2l3
  • Rat genes Nfe2l3
  • Zfish genes nfe2l3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfe2l3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Nfe2l3	IMP		Mouse	MGI:MGI:5572882|PMID:15385560
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Nfe2l3	IDA		Mouse	MGI:MGI:5572882|PMID:15385560
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:O15525	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:Q16621	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:Q16621	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:Q9ULX9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:O15525	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NFE2L3	IPI	UniProtKB:Q9ULX9	Human	PMID:28514442
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfe2l3	IMP		Mouse	MGI:MGI:5572882|PMID:15385560
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFE2L3	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFE2L3	IPI		Human	PMID:23661758
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nfe2l3	IDA		Mouse	MGI:MGI:5572882|PMID:15385560

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern