Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFIA
  • Mouse genes Nfia
  • Rat genes Nfia
  • Zfish genes nfia
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfia

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Nfia	IDA		Mouse	PMID:23407945
Molecular Function	GO:0003677	DNA binding	Nfia	IDA		Mouse	PMID:12955085
Molecular Function	GO:0003677	DNA binding	Nfia	IDA		Rat	PMID:10432316|RGD:61671
Molecular Function	GO:0003677	DNA binding	Nfia	IDA		Rat	PMID:18602130|RGD:2303788
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NFIA	IDA		Human	PMID:17010934
Molecular Function	GO:0140297	DNA-binding transcription factor binding	NFIA	IPI	UniProtKB:Q12948	Human	PMID:15684392
Molecular Function	GO:0005515	protein binding	Nfia	IPI	RGD:62016	Rat	PMID:18602130|RGD:2303788
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFIA	IDA		Human	PMID:17010934
Cellular Component	GO:0030054	cell junction	NFIA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NFIA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFIA	IDA		Human	PMID:15684392
Cellular Component	GO:0005634	nucleus	Nfia	IDA		Mouse	PMID:8306889
Cellular Component	GO:0005634	nucleus	Nfia	IDA		Rat	PMID:18602130|RGD:2303788
Biological Process	GO:0061564	axon development	nfia	IMP	ZFIN:ZDB-GENO-220425-5	Zfish	PMID:33973697
Biological Process	GO:0030509	BMP signaling pathway	Nfia	IMP	MGI:MGI:2449024	Mouse	PMID:29247144
Biological Process	GO:0051216	cartilage development	Nfia	IMP	MGI:MGI:2449024	Mouse	PMID:29247144
Biological Process	GO:0000902	cell morphogenesis	Nfia	IMP	MGI:MGI:2449024	Mouse	PMID:29247144
Biological Process	GO:0044838	cell quiescence	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:33004674
Biological Process	GO:0010458	exit from mitosis	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0010467	gene expression	Nfia	IGI	MGI:MGI:108056	Mouse	PMID:29106906
Biological Process	GO:0010467	gene expression	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0048699	generation of neurons	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:33004674
Biological Process	GO:0021780	glial cell fate specification	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0014009	glial cell proliferation	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0035108	limb morphogenesis	Nfia	IMP	MGI:MGI:2449024	Mouse	PMID:29247144
Biological Process	GO:0061351	neural precursor cell proliferation	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0022008	neurogenesis	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0048665	neuron fate specification	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfia	IDA		Rat	PMID:18602130|RGD:2303788
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFIA	IDA		Human	PMID:17010934
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfia	IDA		Mouse	MGI:MGI:4461125|PMID:19706729
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfia	IDA		Mouse	PMID:9056636
Biological Process	GO:0014070	response to organic cyclic compound	Nfia	IEP		Rat	PMID:18602130|RGD:2303788
Biological Process	GO:0009611	response to wounding	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:33004674
Biological Process	GO:0060041	retina development in camera-type eye	Nfia	IMP	MGI:MGI:6280648	Mouse	PMID:31128945
Biological Process	GO:0060074	synapse maturation	Nfia	IMP		Mouse	PMID:23407945
Biological Process	GO:0072189	ureter development	Nfia	IMP	MGI:MGI:2449024	Mouse	PMID:17530927

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern