Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFIL3
  • Mouse genes Nfil3
  • Rat genes Nfil3
  • Zfish genes nfil3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfil3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfil3	IDA		Rat	PMID:11262393|RGD:633353
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	NFIL3	IDA		Human	PMID:1620116
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	NFIL3	IDA		Human	PMID:20093779
Molecular Function	GO:0042802	identical protein binding	NFIL3	IPI	UniProtKB:Q16649	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	NFIL3	IPI	UniProtKB:Q16649	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P16220	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P18846	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P35638	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q68CJ9	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q9DGW5	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q9Y2J4	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P35638	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q9ULX9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P16220	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:P18846	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:O76083-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q6NUQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q8WWB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q96IK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFIL3	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nfil3	IPI	UniProtKB:Q3UV55	Mouse	MGI:MGI:6282946|PMID:29653076
Molecular Function	GO:0005515	protein binding	Nfil3	IPI	UniProtKB:Q15327	Mouse	MGI:MGI:5294529|PMID:20599664
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFIL3	IDA		Human	PMID:1620116
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfil3	IDA		Mouse	PMID:21460847
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NFIL3	IDA		Human	PMID:20093779
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFIL3	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFIL3	IPI		Human	PMID:23661758
Biological Process	GO:0071353	cellular response to interleukin-4	Nfil3	IDA		Mouse	PMID:9798653
Biological Process	GO:0007507	heart development	nfil3	IMP		Zfish	PMID:20186462
Biological Process	GO:0061515	myeloid cell development	nfil3	IMP	ZFIN:ZDB-MRPHLNO-120912-1	Zfish	PMID:22561072
Biological Process	GO:0001779	natural killer cell differentiation	Nfil3	IMP		Mouse	MGI:MGI:6460593|PMID:32190943
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NFIL3	IDA		Human	PMID:1620116
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nfil3	IDA		Mouse	MGI:MGI:6282985|PMID:30555544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NFIL3	IMP		Human	PMID:20093779
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfil3	IMP		Mouse	MGI:MGI:6282946|PMID:29653076
Biological Process	GO:0010628	positive regulation of gene expression	Nfil3	IMP	MGI:MGI:5005060	Mouse	PMID:21460847
Biological Process	GO:0010628	positive regulation of gene expression	Nfil3	IDA		Mouse	PMID:21460847

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern