Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nfix

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NFIX
- Mouse genes Nfix
- Rat genes Nfix
- Zfish genes nfixa,nfixb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfix

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Nfix	IDA		Mouse	PMID:23964093
Molecular Function	GO:0003682	chromatin binding	Nfix	IMP		Mouse	PMID:29452604
Molecular Function	GO:0003682	chromatin binding	Nfix	IDA		Mouse	PMID:29452604
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nfix	IDA		Mouse	MGI:MGI:5572904\|PMID:9660824
Molecular Function	GO:0005515	protein binding	NFIX	IPI	UniProtKB:Q2TAL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFIX	IPI	UniProtKB:Q8N883	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Nfix	IPI	UniProtKB:Q02078\|UniProtKB:Q02111\|UniProtKB:Q60929	Mouse	MGI:MGI:4454367\|PMID:20178747
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfix	IDA		Mouse	PMID:27880909
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Nfix	IDA		Mouse	MGI:MGI:5572904\|PMID:9660824
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NFIX	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Nfix	IDA		Mouse	PMID:31740002
Biological Process	GO:0048708	astrocyte differentiation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29106906
Biological Process	GO:0048708	astrocyte differentiation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:21800304
Biological Process	GO:1905222	atrioventricular canal morphogenesis	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:25960350
Biological Process	GO:0030282	bone mineralization	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0007420	brain development	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0007420	brain development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0007420	brain development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23964093
Biological Process	GO:0048854	brain morphogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0043010	camera-type eye development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0048469	cell maturation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29452604
Biological Process	GO:0000902	cell morphogenesis	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:25960350
Biological Process	GO:0000902	cell morphogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29452604
Biological Process	GO:0021846	cell proliferation in forebrain	Nfix	IDA		Mouse	PMID:27965439
Biological Process	GO:0021846	cell proliferation in forebrain	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:27965439
Biological Process	GO:0044838	cell quiescence	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23964093
Biological Process	GO:0044838	cell quiescence	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:33004674
Biological Process	GO:0071773	cellular response to BMP stimulus	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23964093
Biological Process	GO:0021696	cerebellar cortex morphogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0021707	cerebellar granule cell differentiation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0021707	cerebellar granule cell differentiation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:21800304
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:21800304
Biological Process	GO:0021549	cerebellum development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:21800304
Biological Process	GO:0021987	cerebral cortex development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0048668	collateral sprouting	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:30272140
Biological Process	GO:0043583	ear development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0001958	endochondral ossification	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0060429	epithelium development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0010458	exit from mitosis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0030900	forebrain development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0021861	forebrain radial glial cell differentiation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:27965439
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23964093
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29452604
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32393888
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:30272140
Biological Process	GO:0010467	gene expression	Nfix	IDA		Mouse	PMID:31740002
Biological Process	GO:0010467	gene expression	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:32938475
Biological Process	GO:0048699	generation of neurons	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:33004674
Biological Process	GO:0021782	glial cell development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0021780	glial cell fate specification	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0014009	glial cell proliferation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0014009	glial cell proliferation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:33004674
Biological Process	GO:0042063	gliogenesis	Nfix	IDA		Mouse	PMID:23042739
Biological Process	GO:0042063	gliogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0042063	gliogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:25331604
Biological Process	GO:0021766	hippocampus development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0021766	hippocampus development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23964093
Biological Process	GO:0021766	hippocampus development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23776487
Biological Process	GO:0021766	hippocampus development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:25331604
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:27965439
Biological Process	GO:0006954	inflammatory response	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0021670	lateral ventricle development	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:25960350
Biological Process	GO:0021670	lateral ventricle development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29452604
Biological Process	GO:0007612	learning	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23776487
Biological Process	GO:0007612	learning	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:30081965
Biological Process	GO:0007612	learning	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0030225	macrophage differentiation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0007613	memory	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23776487
Biological Process	GO:0007613	memory	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29437824
Biological Process	GO:0007613	memory	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:30081965
Biological Process	GO:0007613	memory	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0035264	multicellular organism growth	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:18477394
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29437824
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NFIX	IDA		Human	PMID:19706729
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nfix	IDA		Mouse	MGI:MGI:4461125\|PMID:19706729
Biological Process	GO:0061351	neural precursor cell proliferation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0014016	neuroblast differentiation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29437824
Biological Process	GO:0097402	neuroblast migration	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:25331604
Biological Process	GO:0097402	neuroblast migration	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:30272140
Biological Process	GO:0007405	neuroblast proliferation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:26923583
Biological Process	GO:0022008	neurogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23776487
Biological Process	GO:0022008	neurogenesis	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0022008	neurogenesis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:27965439
Biological Process	GO:0022008	neurogenesis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0022008	neurogenesis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:33004674
Biological Process	GO:0030182	neuron differentiation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29437824
Biological Process	GO:0048665	neuron fate specification	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0021772	olfactory bulb development	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:25331604
Biological Process	GO:0048709	oligodendrocyte differentiation	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:29106906
Biological Process	GO:0048709	oligodendrocyte differentiation	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29437824
Biological Process	GO:0030316	osteoclast differentiation	Nfix	IDA		Mouse	PMID:31740002
Biological Process	GO:0002158	osteoclast proliferation	Nfix	IDA		Mouse	PMID:31740002
Biological Process	GO:0006909	phagocytosis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFIX	IDA		Human	PMID:19706729
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfix	IDA		Mouse	MGI:MGI:5572904\|PMID:9660824
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfix	IDA		Mouse	PMID:21800304
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfix	IDA		Mouse	PMID:9056636
Biological Process	GO:0031099	regeneration	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32393888
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:27880909
Biological Process	GO:0009611	response to wounding	Nfix	IMP		Mouse	PMID:26923583
Biological Process	GO:0009611	response to wounding	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:33004674
Biological Process	GO:0009611	response to wounding	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0060041	retina development in camera-type eye	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:31128945
Biological Process	GO:0007266	Rho protein signal transduction	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0048741	skeletal muscle fiber development	nfixa	IMP	ZFIN:ZDB-MRPHLNO-130425-1	Zfish	PMID:23482488
Biological Process	GO:0014816	skeletal muscle satellite cell differentiation	Nfix	IMP		Mouse	PMID:26923583
Biological Process	GO:0007519	skeletal muscle tissue development	Nfix	IMP		Mouse	PMID:26923583
Biological Process	GO:0007519	skeletal muscle tissue development	nfixa	IMP	ZFIN:ZDB-MRPHLNO-130425-2	Zfish	PMID:23482488
Biological Process	GO:0007519	skeletal muscle tissue development	nfixa	IMP	ZFIN:ZDB-MRPHLNO-130425-1	Zfish	PMID:23482488
Biological Process	GO:0007519	skeletal muscle tissue development	nfixa	IMP	ZFIN:ZDB-MRPHLNO-130425-1	Zfish	PMID:27880909
Biological Process	GO:0007519	skeletal muscle tissue development	nfixa	IGI	ZFIN:ZDB-MRPHLNO-081223-1,ZFIN:ZDB-MRPHLNO-130425-1	Zfish	PMID:27880909
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Nfix	IMP		Mouse	PMID:26923583
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Nfix	IMP		Mouse	PMID:29057908
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:29057908
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32183151
Biological Process	GO:0001501	skeletal system development	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0035176	social behavior	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:30503862
Biological Process	GO:0021510	spinal cord development	Nfix	IMP	MGI:MGI:3714028	Mouse	PMID:17353270
Biological Process	GO:0019827	stem cell population maintenance	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32393888
Biological Process	GO:0001894	tissue homeostasis	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:32393888
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IDA		Mouse	PMID:23964093
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:23042739
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IDA		Mouse	PMID:25960350
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IMP		Mouse	PMID:26923583
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IMP	MGI:MGI:3802571	Mouse	PMID:25331604
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfix	IMP	MGI:MGI:3802570	Mouse	PMID:27965439

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.