Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFKB2
  • Mouse genes Nfkb2
  • Rat genes Nfkb2
  • Zfish genes nfkb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfkb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NFKB2	IDA		Human	PMID:12835724
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q9WUL6	Human	PMID:11239468
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:O00255	Human	PMID:11526476
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P19838	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P25963	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P41279	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q01201	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q04864	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P20749	Human	PMID:16108830
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P63165	Human	PMID:18617892
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P19838	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P19838	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P41279	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P25963	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q01201	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q04864	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:P19838	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	NFKB2	IPI	UniProtKB:Q04206	Human	PMID:8441377
Molecular Function	GO:0005515	protein binding	Nfkb2	IPI	UniProtKB:Q04863	Mouse	MGI:MGI:5449469|PMID:23086447
Molecular Function	GO:0005515	protein binding	Nfkb2	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:5284781|PMID:17254973
Molecular Function	GO:0005515	protein binding	Nfkb2	IPI	UniProtKB:Q04207|UniProtKB:Q04863	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Nfkb2	IPI	RGD:727889	Rat	PMID:18534259|RGD:2302392
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFKB2	IDA		Human	PMID:12835724
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NFKB2	IDA		Human	PMID:28473536
Cellular Component	GO:0033257	Bcl3/NF-kappaB2 complex	NFKB2	IDA		Human	PMID:9407099
Cellular Component	GO:0005737	cytoplasm	NFKB2	IDA		Human	PMID:15677444
Cellular Component	GO:0005829	cytosol	NFKB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Nfkb2	IDA		Rat	PMID:12770614|RGD:2293782
Cellular Component	GO:0005654	nucleoplasm	NFKB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFKB2	IDA		Human	PMID:15677444
Cellular Component	GO:0005634	nucleus	Nfkb2	IDA		Mouse	PMID:10402669
Cellular Component	GO:0005634	nucleus	Nfkb2	IDA		Rat	PMID:18534259|RGD:2302392
Biological Process	GO:0007568	aging	Nfkb2	IEP		Rat	PMID:12020944|RGD:2302396
Biological Process	GO:0001525	angiogenesis	nfkb2	IMP	ZFIN:ZDB-MRPHLNO-171006-5	Zfish	PMID:27913726
Biological Process	GO:0042632	cholesterol homeostasis	nfkb2	IMP	ZFIN:ZDB-MRPHLNO-171006-5	Zfish	PMID:30091016
Biological Process	GO:0030198	extracellular matrix organization	Nfkb2	IMP	MGI:MGI:2179705	Mouse	PMID:10586052
Biological Process	GO:0002268	follicular dendritic cell differentiation	Nfkb2	IMP	MGI:MGI:2179705	Mouse	PMID:10586052
Biological Process	GO:0002467	germinal center formation	Nfkb2	IMP	MGI:MGI:2179705	Mouse	PMID:10586052
Biological Process	GO:0038061	NIK/NF-kappaB signaling	Nfkb2	IDA		Mouse	PMID:23583643
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFKB2	IDA		Human	PMID:12835724
Biological Process	GO:0006355	regulation of DNA-templated transcription	NFKB2	IDA		Human	PMID:8360178
Biological Process	GO:0034097	response to cytokine	Nfkb2	IEP		Rat	PMID:12770614|RGD:2293782
Biological Process	GO:0032496	response to lipopolysaccharide	Nfkb2	IEP		Rat	PMID:12770614|RGD:2293782
Biological Process	GO:0048536	spleen development	Nfkb2	IMP	MGI:MGI:2179705	Mouse	PMID:10586052

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern