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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nfkbia

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfkbia
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0019899enzyme bindingNFKBIAIPIUniProtKB:P55345HumanPMID:16648481
Molecular FunctionGO:0031072heat shock protein bindingNfkbiaIPIRGD:2840RatPMID:16135962|RGD:1598788
Molecular FunctionGO:0042802identical protein bindingNFKBIAIPIUniProtKB:P25963HumanPMID:16951195
Molecular FunctionGO:0051059NF-kappaB bindingNFKBIAIDAHumanPMID:11931770
Molecular FunctionGO:0051059NF-kappaB bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:7739562
Molecular FunctionGO:0051059NF-kappaB bindingNfkbiaIPIRGD:70498RatPMID:16135962|RGD:1598788
Molecular FunctionGO:0008139nuclear localization sequence bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:1493333
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:10498867
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:10733566
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q60680-2HumanPMID:10733566
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9UKB1HumanPMID:12482991
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:12486103
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:12486103
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:12730857
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:14685242
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q8N668HumanPMID:14685242
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q00653HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206-2HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04864HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9UKB1HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y6K9HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q96EY1-1HumanPMID:15601829
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q96EY1-2HumanPMID:15601829
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:15799966
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:16126728
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y6K9HumanPMID:16126728
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P06239HumanPMID:16195219
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:16286467
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:16286467
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:16319058
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y6K9HumanPMID:16319058
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:16365431
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:16683270
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:16951195
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:17003112
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:17003112
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9NWT6HumanPMID:17003112
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:17301240
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P0CG48HumanPMID:17318178
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:17612295
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P23396HumanPMID:18045535
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P0CG48HumanPMID:18539148
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9J0X9HumanPMID:18539148
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P21530:PRO_0000038062HumanPMID:18632959
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:18922877
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P25098HumanPMID:19008357
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P34947HumanPMID:19008357
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:19196987
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:19345327
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9UKB1HumanPMID:20347421
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:21217772
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y6K9HumanPMID:21217772
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:21399639
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:21423167
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:21765415
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:21765415
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9E7P0HumanPMID:22014111
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:22037600
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y3V2HumanPMID:23469069
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:23563313
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:23602409
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q96HY6HumanPMID:23675531
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:23850221
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P23396HumanPMID:24457201
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:24457201
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P35221HumanPMID:24509793
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:24634218
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P14340HumanPMID:24973451
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P14340:PRO_0000037965HumanPMID:24973451
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q14511HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:25609649
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:25609694
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:25759022
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:25759022
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04864HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9Y6K9HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9NWT6HumanPMID:26972000
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q00653HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206-2HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04864HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9NWT6HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:29734393
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O43242HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P56279HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q14511-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q96HA1-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q9H0I2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:35140242
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P55072HumanPMID:9452483
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O14920HumanPMID:9520446
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:O15111HumanPMID:9520446
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:P19838HumanPMID:9865693
Molecular FunctionGO:0005515protein bindingNFKBIAIPIUniProtKB:Q04206HumanPMID:9865693
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5284781|PMID:17254973
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q5SRY7MouseMGI:MGI:2176150|PMID:11896578
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5515848|PMID:23850221
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:3688344|PMID:15102471
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:O88895MouseMGI:MGI:3694287|PMID:16371367
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:4821660|PMID:20740013
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5916190|PMID:20634424
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5493209|PMID:21706061
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04863MouseMGI:MGI:5449469|PMID:23086447
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5449469|PMID:23086447
Molecular FunctionGO:0005515protein bindingNfkbiaIPIUniProtKB:Q04207MouseMGI:MGI:5508593|PMID:18401342
Molecular FunctionGO:0005515protein bindingNfkbiaIPIPR:P02340MousePMID:11799106
Molecular FunctionGO:0005515protein bindingNfkbiaIPIPR:P63280MousePMID:9223278
Molecular FunctionGO:0140311protein sequestering activityNFKBIAIDAHumanPMID:1493333
Molecular FunctionGO:0044877protein-containing complex bindingNfkbiaIPIRGD:2741|RGD:727889RatPMID:12672265|RGD:1581614
Molecular FunctionGO:0031625ubiquitin protein ligase bindingNFKBIAIPIUniProtKB:Q9Y297HumanPMID:9859996
Cellular ComponentGO:0005737cytoplasmNFKBIAIDAHumanPMID:1493333
Cellular ComponentGO:0005737cytoplasmNFKBIAIDAHumanPMID:3140380
Cellular ComponentGO:0005737cytoplasmNfkbiaIDAMousePMID:11799106
Cellular ComponentGO:0005737cytoplasmNfkbiaIDAMousePMID:21874024
Cellular ComponentGO:0005737cytoplasmNfkbiaIDARatPMID:9343439|RGD:2298908
Cellular ComponentGO:0005829cytosolNFKBIAIDAHumanGO_REF:0000052
Cellular ComponentGO:0005829cytosolNfkbiaIDAMousePMID:11799106
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:10620707|RGD:2298882
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:10841371|RGD:2298883
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:11058855|RGD:2298912
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:16135962|RGD:1598788
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:19414010|RGD:10402041
Cellular ComponentGO:0005829cytosolNfkbiaIDARatPMID:9918814|RGD:2298880
Cellular ComponentGO:0005634nucleusNFKBIAIDAHumanPMID:16648481
Cellular ComponentGO:0005634nucleusNFKBIAIDAHumanPMID:7679069
Cellular ComponentGO:0005634nucleusNfkbiaIDAMousePMID:11799106
Cellular ComponentGO:0005634nucleusNfkbiaIDARatPMID:10841371|RGD:2298883
Cellular ComponentGO:0005886plasma membraneNFKBIAIDAHumanGO_REF:0000052
Cellular ComponentGO:0032991protein-containing complexNfkbiaIDARatPMID:16135962|RGD:1598788
Biological ProcessGO:0050853B cell receptor signaling pathwayNfkbiaIDAMousePMID:17367755
Biological ProcessGO:0071216cellular response to biotic stimulusNfkbiaIDAMousePMID:23262141
Biological ProcessGO:0071345cellular response to cytokine stimulusNfkbiaIDARatPMID:19414010|RGD:10402041
Biological ProcessGO:0071407cellular response to organic cyclic compoundNfkbiaIDARatPMID:19414010|RGD:10402041
Biological ProcessGO:0071356cellular response to tumor necrosis factorNfkbiaIDAMousePMID:24349514
Biological ProcessGO:0007253cytoplasmic sequestering of NF-kappaBNFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0007253cytoplasmic sequestering of NF-kappaBNfkbiaIMPRatPMID:10620707|RGD:2298882
Biological ProcessGO:0007253cytoplasmic sequestering of NF-kappaBNfkbiaIMPRatPMID:16580131|RGD:2298917
Biological ProcessGO:0007253cytoplasmic sequestering of NF-kappaBNfkbiaIMPRatPMID:9343439|RGD:2298908
Biological ProcessGO:0007253cytoplasmic sequestering of NF-kappaBNfkbiaIMPRatPMID:9918814|RGD:2298880
Biological ProcessGO:0042994cytoplasmic sequestering of transcription factorNFKBIAIDAHumanPMID:1493333
Biological ProcessGO:0007249I-kappaB kinase/NF-kappaB signalingNFKBIAIDAHumanPMID:1493333
Biological ProcessGO:0007249I-kappaB kinase/NF-kappaB signalingNFKBIAIDAHumanPMID:25038658
Biological ProcessGO:0002523leukocyte migration involved in inflammatory responseNfkbiaIEPRatPMID:27939985|RGD:15036816
Biological ProcessGO:0031663lipopolysaccharide-mediated signaling pathwayNfkbiaIDAMousePMID:18261938
Biological ProcessGO:0031663lipopolysaccharide-mediated signaling pathwayNfkbiaIDAMousePMID:12872135
Biological ProcessGO:0097421liver regenerationNfkbiaIEPRatPMID:24446557|RGD:150429839
Biological ProcessGO:1901533negative regulation of hematopoietic progenitor cell differentiationnfkbiaaIMPZFIN:ZDB-MRPHLNO-150818-1ZfishPMID:25540193
Biological ProcessGO:0010888negative regulation of lipid storageNFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0010745negative regulation of macrophage derived foam cell differentiationNFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0045638negative regulation of myeloid cell differentiationNfkbiaIMPMGI:MGI:2176180,MGI:MGI:3577709MousePMID:15845452
Biological ProcessGO:0032088negative regulation of NF-kappaB transcription factor activityNFKBIAIDAHumanPMID:11931770
Biological ProcessGO:0045746negative regulation of Notch signaling pathwayNfkbiaIMPMGI:MGI:2176180,MGI:MGI:3577709MousePMID:15845452
Biological ProcessGO:0038061NIK/NF-kappaB signalingNFKBIAIDAHumanPMID:1493333
Biological ProcessGO:0038061NIK/NF-kappaB signalingNFKBIAIDAHumanPMID:25038658
Biological ProcessGO:0007219Notch signaling pathwayNfkbiaIMPMGI:MGI:2176180,MGI:MGI:3577709MousePMID:15845452
Biological ProcessGO:0070427nucleotide-binding oligomerization domain containing 1 signaling pathwayNfkbiaIDAMousePMID:18261938
Biological ProcessGO:0070431nucleotide-binding oligomerization domain containing 2 signaling pathwayNfkbiaIDAMousePMID:18261938
Biological ProcessGO:0010875positive regulation of cholesterol effluxNFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionNfkbiaIMPMousePMID:18505784
Biological ProcessGO:0050729positive regulation of inflammatory responseNFKBIAIDAHumanPMID:25038658
Biological ProcessGO:0051247positive regulation of protein metabolic processNFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINFKBIAIMPHumanPMID:16938301
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINFKBIAIDAHumanPMID:19245366
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINFKBIAIDAHumanPMID:23729669
Biological ProcessGO:0060261positive regulation of transcription initiation by RNA polymerase IINfkbiaIMPMousePMID:16322095
Biological ProcessGO:0006606protein import into nucleusNfkbiaIDAMousePMID:11799106
Biological ProcessGO:0042127regulation of cell population proliferationNfkbiaIDAMousePMID:11799106
Biological ProcessGO:0010468regulation of gene expressionNfkbiaIMPMousePMID:21737317
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationnfkbiaaIGIZFIN:ZDB-GENE-040219-3ZfishPMID:25540193
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationnfkbiaaIGIZFIN:ZDB-GENE-070410-133ZfishPMID:25540193
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationnfkbiaaIGIZFIN:ZDB-GENE-080104-4ZfishPMID:25540193
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationnfkbiaaIGIZFIN:ZDB-GENE-040219-9ZfishPMID:25540193
Biological ProcessGO:0045471response to ethanolNfkbiaIEPRatPMID:27939985|RGD:15036816
Biological ProcessGO:0043330response to exogenous dsRNANfkbiaIDAMousePMID:12872135
Biological ProcessGO:0032496response to lipopolysaccharideNfkbiaIDAMousePMID:12872135
Biological ProcessGO:0032495response to muramyl dipeptideNfkbiaIDAMousePMID:15692051
Biological ProcessGO:0035994response to muscle stretchNfkbiaIDAMousePMID:20442316
Biological ProcessGO:0014070response to organic cyclic compoundNfkbiaIEPRatPMID:27939985|RGD:15036816
Biological ProcessGO:0009615response to virusnfkbiaaIDAZfishPMID:17371995
Biological ProcessGO:0034142toll-like receptor 4 signaling pathwayNfkbiaIDAMousePMID:18261938
Biological ProcessGO:0033209tumor necrosis factor-mediated signaling pathwayNFKBIAIDAHumanPMID:25038658

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory